Donepezil+ chromone+ melatonin hybrids as promising agents for Alzheimer’s disease therapy I Pachón-Angona, B Refouvelet, R Andrýs, H Martin, V Luzet, I Iriepa, ... Journal of Enzyme Inhibition and Medicinal Chemistry 34 (1), 479-489, 2019 | 47 | 2019 |
New Dual Small Molecules for Alzheimer’s Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with … R Malek, RL Arribas, A Palomino-Antolin, P Totoson, C Demougeot, ... Journal of medicinal chemistry 62 (24), 11416-11422, 2019 | 34 | 2019 |
Tacrines as therapeutic agents for alzheimer's disease. V. recent developments ÓM Bautista‐Aguilera, L Ismaili, I Iriepa, D Diez‐Iriepa, F Chabchoub, ... The Chemical Record 21 (1), 162-174, 2021 | 30 | 2021 |
Novel quinolylnitrones combining neuroprotective and antioxidant properties M Chioua, M Salgado-Ramos, D Diez-Iriepa, A Escobar-Peso, I Iriepa, ... ACS Chemical Neuroscience 10 (6), 2703-2706, 2019 | 18 | 2019 |
Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models B Chamorro, D Diez-Iriepa, B Merás-Sáiz, M Chioua, D García-Vieira, ... Scientific Reports 10 (1), 14150, 2020 | 16 | 2020 |
QuinoxalineTacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy E Ramos, A Palomino-Antolín, M Bartolini, I Iriepa, I Moraleda, ... Molecules 24 (8), 1503, 2019 | 13 | 2019 |
Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout P Narros-Fernández, M Chioua, SA Petcu, D Diez-Iriepa, ... Journal of medicinal chemistry 65 (8), 6250-6260, 2022 | 12 | 2022 |
Triazolopyridopyrimidine: A new scaffold for dual-target small molecules for Alzheimer’s disease therapy L Zribi, I Pachòn-Angona, ÒM Bautista-Aguilera, D Diez-Iriepa, ... Molecules 25 (14), 3190, 2020 | 11 | 2020 |
Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones A Jiménez-Almarza, D Diez-Iriepa, M Chioua, B Chamorro, I Iriepa, ... Bioorganic Chemistry 86, 445-451, 2019 | 11 | 2019 |
Homo-Tris-Nitrones Derived from α-Phenyl-N-tert-butylnitrone: Synthesis, Neuroprotection and Antioxidant Properties D Diez-Iriepa, B Chamorro, M Talaván, M Chioua, I Iriepa, ... International Journal of Molecular Sciences 21 (21), 7949, 2020 | 10 | 2020 |
Privileged quinolylnitrones for the combined therapy of ischemic stroke and Alzheimer’s disease JM Alonso, A Escobar-Peso, A Palomino-Antolín, D Diez-Iriepa, M Chioua, ... Pharmaceuticals 14 (9), 861, 2021 | 5 | 2021 |
Studies on the Affinity of 6-[(n-(Cyclo) aminoalkyl) oxy]-4 H-chromen-4-ones for Sigma 1/2 Receptors W Deuther-Conrad, D Diez-Iriepa, I Iriepa, F López-Muñoz, ... RSC Medicinal Chemistry 12 (6), 1000-1004, 2021 | 5 | 2021 |
8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases D Knez, D Diez-Iriepa, M Chioua, A Gottinger, M Denic, F Chantegreil, ... Acta Pharmaceutica Sinica B 13 (5), 2152-2175, 2023 | 4 | 2023 |
Polyfunctionalized α-Phenyl-tert-butyl (benzyl) nitrones: Multifunctional Antioxidants for Stroke Treatment D Diez-Iriepa, D Knez, S Gobec, I Iriepa, C de Los Ríos, I Bravo, ... Antioxidants 11 (9), 1735, 2022 | 4 | 2022 |
Synthesis and Antioxidant Properties of HeteroBisNitrones Derived from Benzene Dicarbaldehydes D Diez-Iriepa, I Iriepa, F López-Muñoz, J Marco-Contelles, ... Antioxidants 11 (8), 1575, 2022 | 2 | 2022 |
Synthesis, Neuroprotection, and Antioxidant Activity of 1,1′-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models B Chamorro, D García-Vieira, D Diez-Iriepa, E Garagarza, M Chioua, ... Molecules 26 (4), 1127, 2021 | 2 | 2021 |
Synthesis of (±)‐cis‐1‐Aryl‐3‐oxo‐2,3‐dihydro‐1H‐benzo[f]chromene‐2‐carbonitriles and (±)‐trans‐4‐Aryl‐2‐oxo‐3,4‐dihydro‐2H‐benzo[h]chromene‐3 … K Mkaouar, I Iriepa, D Diez‐Iriepa, J Marco‐Contelles, L Ismaili, ... ChemistrySelect 4 (44), 12902-12905, 2019 | 2 | 2019 |
QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer’s Disease Therapy E Ramos Alonso, A Palomino-Antolín, M Bartolini, I Iriepa, I Moraleda, ... MDPI, 2019 | 1 | 2019 |
Contilistat, a new polyfunctionalized histone deacetylase inhibitor, showing potential capacity to inhibit cholinesterase/monoamine oxidase enzymes, and modulate histamine 3 … J Marco-Contelles, D Diez-Iriepa, M Toledano-Pinedo, A Porro, ... | | 2023 |
Design, synthesis, computational study, and biological evaluation of new molecules for the treatment of age-related diseases D Diez Iriepa | | 2023 |