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Diez-Iriepa, Daniel
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Donepezil+ chromone+ melatonin hybrids as promising agents for Alzheimer’s disease therapy
I Pachón-Angona, B Refouvelet, R Andrýs, H Martin, V Luzet, I Iriepa, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 34 (1), 479-489, 2019
472019
New Dual Small Molecules for Alzheimer’s Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with …
R Malek, RL Arribas, A Palomino-Antolin, P Totoson, C Demougeot, ...
Journal of medicinal chemistry 62 (24), 11416-11422, 2019
342019
Tacrines as therapeutic agents for alzheimer's disease. V. recent developments
ÓM Bautista‐Aguilera, L Ismaili, I Iriepa, D Diez‐Iriepa, F Chabchoub, ...
The Chemical Record 21 (1), 162-174, 2021
302021
Novel quinolylnitrones combining neuroprotective and antioxidant properties
M Chioua, M Salgado-Ramos, D Diez-Iriepa, A Escobar-Peso, I Iriepa, ...
ACS Chemical Neuroscience 10 (6), 2703-2706, 2019
182019
Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models
B Chamorro, D Diez-Iriepa, B Merás-Sáiz, M Chioua, D García-Vieira, ...
Scientific Reports 10 (1), 14150, 2020
162020
QuinoxalineTacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy
E Ramos, A Palomino-Antolín, M Bartolini, I Iriepa, I Moraleda, ...
Molecules 24 (8), 1503, 2019
132019
Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout
P Narros-Fernández, M Chioua, SA Petcu, D Diez-Iriepa, ...
Journal of medicinal chemistry 65 (8), 6250-6260, 2022
122022
Triazolopyridopyrimidine: A new scaffold for dual-target small molecules for Alzheimer’s disease therapy
L Zribi, I Pachòn-Angona, ÒM Bautista-Aguilera, D Diez-Iriepa, ...
Molecules 25 (14), 3190, 2020
112020
Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones
A Jiménez-Almarza, D Diez-Iriepa, M Chioua, B Chamorro, I Iriepa, ...
Bioorganic Chemistry 86, 445-451, 2019
112019
Homo-Tris-Nitrones Derived from α-Phenyl-N-tert-butylnitrone: Synthesis, Neuroprotection and Antioxidant Properties
D Diez-Iriepa, B Chamorro, M Talaván, M Chioua, I Iriepa, ...
International Journal of Molecular Sciences 21 (21), 7949, 2020
102020
Privileged quinolylnitrones for the combined therapy of ischemic stroke and Alzheimer’s disease
JM Alonso, A Escobar-Peso, A Palomino-Antolín, D Diez-Iriepa, M Chioua, ...
Pharmaceuticals 14 (9), 861, 2021
52021
Studies on the Affinity of 6-[(n-(Cyclo) aminoalkyl) oxy]-4 H-chromen-4-ones for Sigma 1/2 Receptors
W Deuther-Conrad, D Diez-Iriepa, I Iriepa, F López-Muñoz, ...
RSC Medicinal Chemistry 12 (6), 1000-1004, 2021
52021
8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases
D Knez, D Diez-Iriepa, M Chioua, A Gottinger, M Denic, F Chantegreil, ...
Acta Pharmaceutica Sinica B 13 (5), 2152-2175, 2023
42023
Polyfunctionalized α-Phenyl-tert-butyl (benzyl) nitrones: Multifunctional Antioxidants for Stroke Treatment
D Diez-Iriepa, D Knez, S Gobec, I Iriepa, C de Los Ríos, I Bravo, ...
Antioxidants 11 (9), 1735, 2022
42022
Synthesis and Antioxidant Properties of HeteroBisNitrones Derived from Benzene Dicarbaldehydes
D Diez-Iriepa, I Iriepa, F López-Muñoz, J Marco-Contelles, ...
Antioxidants 11 (8), 1575, 2022
22022
Synthesis, Neuroprotection, and Antioxidant Activity of 1,1′-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models
B Chamorro, D García-Vieira, D Diez-Iriepa, E Garagarza, M Chioua, ...
Molecules 26 (4), 1127, 2021
22021
Synthesis of (±)‐cis‐1‐Aryl‐3‐oxo‐2,3‐dihydro‐1H‐benzo[f]chromene‐2‐carbonitriles and (±)‐trans‐4‐Aryl‐2‐oxo‐3,4‐dihydro‐2H‐benzo[h]chromene‐3 …
K Mkaouar, I Iriepa, D Diez‐Iriepa, J Marco‐Contelles, L Ismaili, ...
ChemistrySelect 4 (44), 12902-12905, 2019
22019
QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer’s Disease Therapy
E Ramos Alonso, A Palomino-Antolín, M Bartolini, I Iriepa, I Moraleda, ...
MDPI, 2019
12019
Contilistat, a new polyfunctionalized histone deacetylase inhibitor, showing potential capacity to inhibit cholinesterase/monoamine oxidase enzymes, and modulate histamine 3 …
J Marco-Contelles, D Diez-Iriepa, M Toledano-Pinedo, A Porro, ...
2023
Design, synthesis, computational study, and biological evaluation of new molecules for the treatment of age-related diseases
D Diez Iriepa
2023
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Articles 1–20