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Theinmozhi Arulraj
Theinmozhi Arulraj
Postdoctoral fellow, Johns Hopkins University
Verified email at jhmi.edu
Title
Cited by
Cited by
Year
Mathematical modeling identifies Lck as a potential mediator for PD-1 induced inhibition of early TCR signaling
T Arulraj, D Barik
PloS one 13 (10), e0206232, 2018
282018
Synchronous germinal center onset impacts the efficiency of antibody responses
T Arulraj, SC Binder, PA Robert, M Meyer-Hermann
Frontiers in immunology 10, 440306, 2019
202019
Ymir: A 3D structural affinity model for multi-epitope vaccine simulations
PA Robert, T Arulraj, M Meyer-Hermann
Iscience 24 (9), 2021
182021
Germinal centre shutdown
T Arulraj, SC Binder, PA Robert, M Meyer-Hermann
Frontiers in immunology 12, 705240, 2021
182021
Rate of immune complex cycling in follicular dendritic cells determines the extent of protecting antigen integrity and availability to germinal center B cells
T Arulraj, SC Binder, M Meyer-Hermann
The Journal of Immunology 206 (7), 1436-1442, 2021
172021
BTG1 mutation yields supercompetitive B cells primed for malignant transformation
C Mlynarczyk, M Teater, J Pae, CR Chin, L Wang, T Arulraj, D Barisic, ...
Science 379 (6629), eabj7412, 2023
132023
A mathematical modelling tool for unravelling the antibody-mediated effects on CTLA-4 interactions
A Ganesan, T Arulraj, T Choulli, KH Barakat
BMC Medical Informatics and Decision Making 18, 1-17, 2018
72018
A transcriptome-informed QSP model of metastatic triple-negative breast cancer identifies predictive biomarkers for PD-1 inhibition
T Arulraj, H Wang, LA Emens, CA Santa-Maria, AS Popel
Science Advances 9 (26), eadg0289, 2023
62023
Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition
H Wang, T Arulraj, H Kimko, AS Popel
NPJ Precision Oncology 7 (1), 55, 2023
62023
Investigating the mechanism of germinal center shutdown
T Arulraj, SC Binder, M Meyer-Hermann
Frontiers in Immunology 13, 922318, 2022
42022
Antibody mediated intercommunication of germinal centers
T Arulraj, SC Binder, M Meyer-Hermann
Cells 11 (22), 3680, 2022
22022
BTG1 Mutation Promotes Aggressive Lymphoma Development By Lowering the Threshold to MYC Activation and Generating “Super-Competitor” B Cells
C Mlynarczyk, M Teater, J Pae, T Arulraj, CR Chin, L Wang, J Ersching, ...
Blood 138, 359, 2021
12021
In Silico Analysis of the Longevity and Timeline of Individual Germinal Center Reactions in a Primary Immune Response
T Arulraj, SC Binder, M Meyer-Hermann
Cells 10 (7), 1736, 2021
12021
Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology
T Arulraj, H Wang, A Ippolito, S Zhang, EJ Fertig, AS Popel
Briefings in bioinformatics 25 (3), bbae131, 2024
2024
From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling
H Wang, T Arulraj, A Ippolito, AS Popel
arXiv preprint arXiv:2403.03335, 2024
2024
Germinal centers are permissive to subdominant antibody responses
PA Robert, T Arulraj, M Meyer-Hermann
Frontiers in Immunology 14, 1238046, 2024
2024
Predicting response to PD-L1 inhibition in NSCLC using a quantitative systems pharmacology model guided by immunogenomic data
H Wang, T Arulraj, AS Popel
Cancer Research 83 (7_Supplement), 5697-5697, 2023
2023
In silico analysis of the mechanism and regulation of germinal center shutdown
T Arulraj
2021
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