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Toshio Hirano
Toshio Hirano
Osaka University and National Institutes for Quantum Science and Technology
Verified email at alumni.osaka-u.ac.jp
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Cited by
Year
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin
T Hirano, K Yasukawa, H Harada, T Taga, Y Watanabe, T Matsuda, ...
Nature 324 (6092), 73-76, 1986
28501986
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
M Kawano, T Hirano, T Matsuda, T Taga, Y Horii, K Iwato, H Asaoku, ...
Nature 332 (6159), 83-85, 1988
21251988
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
T Taga, M Hibi, Y Hirata, K Yamasaki, K Yasukawa, T Matsuda, T Hirano, ...
Cell 58 (3), 573-581, 1989
18821989
A nuclear factor for IL‐6 expression (NF‐IL6) is a member of a C/EBP family.
S Akira, H Isshiki, T Sugita, O Tanabe, S Kinoshita, Y Nishio, T Nakajima, ...
The EMBO journal 9 (6), 1897-1906, 1990
18721990
Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF)
S Akira, T Hirano, T Taga, T Kishimoto
The FASEB journal 4 (11), 2860-2867, 1990
17691990
Molecular cloning and expression of an IL-6 signal transducer, gp130
M Hibi, M Murakami, M Saito, T Hirano, T Taga, T Kishimoto
Cell 63 (6), 1149-1157, 1990
16761990
Biological and clinical aspects of interleukin 6
T Hirano, S Akira, T Taga, T Kishimoto
Immunology today 11, 443-449, 1990
15401990
Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
T Hirano, K Ishihara, M Hibi
Oncogene 19 (21), 2548-2556, 2000
15232000
Cloning and expression of the human interleukin-6 (BSF-2/IFNβ 2) receptor
K Yamasaki, T Taga, Y Hirata, H Yawata, Y Kawanishi, B Seed, ...
Science 241 (4867), 825-828, 1988
14841988
IL-6 is produced by osteoblasts and induces bone resorption.
Y Ishimi, C Miyaura, CH Jin, T Akatsu, E Abe, Y Nakamura, A Yamaguchi, ...
Journal of Immunology (Baltimore, Md.: 1950) 145 (10), 3297-3303, 1990
14401990
Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease
K Yoshizaki, T Matsuda, N Nishimoto, T Kuritani, L Taeho, K Aozasa, ...
11741989
IL-6 in autoimmune disease and chronic inflammatory proliferative disease
K Ishihara, T Hirano
Cytokine & growth factor reviews 13 (4-5), 357-368, 2002
10852002
The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells.
A Muraguchi, T Hirano, BO Tang, T Matsuda, Y Horii, K Nakajima, ...
The Journal of experimental medicine 167 (2), 332-344, 1988
10671988
Interleukin 6 and its receptor: ten years later
T Hirano
International reviews of immunology 16 (3-4), 249-284, 1998
10461998
Excessive production of interleukin 6/B cell stimulatory factor‐2 in rheumatoid arthritis
T Hirano, T Matsuda, M Turner, N Miyasaka, G Buchan, B Tang, K Sato, ...
European journal of immunology 18 (11), 1797-1802, 1988
10261988
Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).
T Hirano, T Taga, N Nakano, K Yasukawa, S Kashiwamura, K Shimizu, ...
Proceedings of the National Academy of Sciences 82 (16), 5490-5494, 1985
9881985
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
H Yasukawa, M Ohishi, H Mori, M Murakami, T Chinen, D Aki, T Hanada, ...
Nature immunology 4 (6), 551-556, 2003
9352003
IL-6 signal transduction and its physiological roles: the signal orchestration model
D Kamimura, K Ishihara, T Hirano
Reviews of physiology, biochemistry and pharmacology, 1-38, 2004
9002004
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis
T Fukada, M Hibi, Y Yamanaka, M Takahashi-Tezuka, Y Fujitani, ...
Immunity 5 (5), 449-460, 1996
8511996
IgG1 plasmacytosis in interleukin 6 transgenic mice.
S Suematsu, T Matsuda, K Aozasa, S Akira, N Nakano, S Ohno, ...
Proceedings of the National Academy of Sciences 86 (19), 7547-7551, 1989
7981989
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