Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPRmt to promote metastasis TC Kenny, P Hart, M Ragazzi, M Sersinghe, J Chipuk, MAK Sagar, ... Oncogene 36 (31), 4393-4404, 2017 | 94 | 2017 |
Mitohormesis primes tumor invasion and metastasis TC Kenny, AJ Craig, A Villanueva, D Germain Cell reports 27 (8), 2292-2303. e6, 2019 | 73 | 2019 |
Mitohormesis, UPRmt, and the complexity of mitochondrial DNA landscapes in cancer TC Kenny, ML Gomez, D Germain Cancer research 79 (24), 6057-6066, 2019 | 44 | 2019 |
SOD1 is essential for oncogene-driven mammary tumor formation but dispensable for normal development and proliferation ML Gomez, N Shah, TC Kenny, EC Jenkins Jr, D Germain Oncogene 38 (29), 5751-5765, 2019 | 42 | 2019 |
mtDNA, Metastasis, and the Mitochondrial Unfolded Protein Response (UPRmt) TC Kenny, D Germain Frontiers in Cell and Developmental Biology 5, 37, 2017 | 38 | 2017 |
The mitochondrial unfolded protein response as a non-oncogene addiction to support adaptation to stress during transformation in cancer and beyond TC Kenny, G Manfredi, D Germain Frontiers in oncology 7, 159, 2017 | 33 | 2017 |
Proteasome mapping reveals sexual dimorphism in tissue‐specific sensitivity to protein aggregations EC Jenkins, N Shah, M Gomez, G Casalena, D Zhao, TC Kenny, ... EMBO reports 21 (4), e48978, 2020 | 27 | 2020 |
Patient-derived interstitial fluids and predisposition to aggressive sporadic breast cancer through collagen remodeling and inactivation of p53 TC Kenny, H Schmidt, K Adelson, Y Hoshida, AP Koh, N Shah, J Mandeli, ... Clinical cancer research 23 (18), 5446-5459, 2017 | 22 | 2017 |
Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals TC Kenny, A Khan, Y Son, L Yue, S Heissel, A Sharma, HA Pasolli, Y Liu, ... Cell metabolism 35 (6), 1057-1071. e12, 2023 | 21 | 2023 |
From discovery of the CHOP axis and targeting ClpP to the identification of additional axes of the UPRmt driven by the estrogen receptor and SIRT3 TC Kenny, D Germain Journal of Bioenergetics and Biomembranes 49, 297-305, 2017 | 21 | 2017 |
Widespread implications of ACOSOG Z0011: effect on total mastectomy patients TC Kenny, J Dove, M Shabahang, N Woll, M Hunsinger, A Morgan, ... The American Surgeon 82 (1), 53-58, 2016 | 15 | 2016 |
Autoregulatory control of mitochondrial glutathione homeostasis Y Liu, S Liu, A Tomar, FS Yen, G Unlu, N Ropek, RA Weber, Y Wang, ... Science 382 (6672), 820-828, 2023 | 14 | 2023 |
Mitochondrial dysfunction in breast cancer AK Riar, TC Kenny, Y Takabatake, L Papa, D Germain Research and Reports in Biology, 137-145, 2015 | 9 | 2015 |
Raloxifene is a female-specific proteostasis therapeutic in the spinal cord EC Jenkins, G Casalena, M Gomez, D Zhao, TC Kenny, N Shah, ... Endocrinology 162 (2), bqaa221, 2021 | 5 | 2021 |
Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1 Y Son, TC Kenny, A Khan, K Birsoy, RK Hite Nature, 1-7, 2024 | 3 | 2024 |
Mitochondria and Cancer TC Kenny, K Birsoy Cold Spring Harbor Perspectives in Medicine, a041534, 2024 | | 2024 |
GeneMAP: A discovery platform for metabolic gene function A Khan, G Unlu, P Lin, Y Liu, E Kilic, TC Kenny, K Birsoy, ER Gamazon bioRxiv, 2023 | | 2023 |
GeneMAP: A discovery platform for metabolic gene function K Birsoy, E Gamazon, A Khan, G Unlu, P Lin, Y Liu, E Kilic, TC Kenny bioRxiv, 2023.12. 07.570588, 2023 | | 2023 |
Integrative genetic analysis identifies FLVCR1 as an essential component of choline transport in mammals TC Kenny, A Khan, Y Son, L Yue, S Heissel, ER Gamazon, H Alwaseem, ... bioRxiv, 2022.10. 05.509986, 2022 | | 2022 |
Mitohormesis Primes Tumor Invasion and Metastasis TC Kenny, D Germain FREE RADICAL BIOLOGY AND MEDICINE 159, S9-S9, 2020 | | 2020 |