TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis Y Matsuo, JH Park, T Miyamoto, S Yamamoto, S Hisada, H Alachkar, ... Science translational medicine 6 (259), 259ra145-259ra145, 2014 | 126 | 2014 |
Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients PY Yew, H Alachkar, R Yamaguchi, K Kiyotani, H Fang, KL Yap, HT Liu, ... Bone marrow transplantation 50 (9), 1227-1234, 2015 | 123 | 2015 |
WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck V Saloura, HS Cho, K Kiyotani, H Alachkar, Z Zuo, M Nakakido, ... Molecular Cancer Research 13 (2), 293-304, 2015 | 121 | 2015 |
Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia S Wu, Y Du, J Beckford, H Alachkar Journal of translational medicine 16, 1-9, 2018 | 114 | 2018 |
Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia J Khalife, HS Radomska, R Santhanam, X Huang, P Neviani, J Saultz, ... Leukemia 29 (10), 1981-1992, 2015 | 85 | 2015 |
Nicotinic α5 receptor subunit mRNA expression is associated with distant 5′ upstream polymorphisms RM Smith, H Alachkar, AC Papp, D Wang, DC Mash, JC Wang, LJ Bierut, ... European Journal of Human Genetics 19 (1), 76-83, 2011 | 77 | 2011 |
Deciphering the TCR repertoire to solve the COVID-19 mystery L Gutierrez, J Beckford, H Alachkar Trends in pharmacological sciences 41 (8), 518-530, 2020 | 71 | 2020 |
Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia H Alachkar, R Santhanam, JG Harb, DM Lucas, JJ Oaks, CJ Hickey, ... Journal of hematology & oncology 6, 1-12, 2013 | 69 | 2013 |
Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia H Alachkar, MBG Mutonga, KH Metzeler, N Fulton, G Malnassy, T Herold, ... Oncotarget 5 (23), 12371, 2014 | 68 | 2014 |
Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia CJ Hickey, S Schwind, HS Radomska, AM Dorrance, R Santhanam, ... Blood, The Journal of the American Society of Hematology 121 (1), 159-169, 2013 | 67 | 2013 |
SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome H Alachkar, R Santhanam, K Maharry, KH Metzeler, X Huang, ... The Journal of clinical investigation 124 (4), 1512-1524, 2014 | 66 | 2014 |
Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and asparaginase induced hepatotoxicity in adult patients with acute lymphoblastic leukemia H Alachkar, N Fulton, B Sanford, G Malnassy, M Mutonga, RA Larson, ... The pharmacogenomics journal 17 (3), 274-279, 2017 | 51 | 2017 |
Diversity in immunogenomics: the value and the challenge K Peng, Y Safonova, M Shugay, AB Popejoy, OL Rodriguez, F Breden, ... Nature methods 18 (6), 588-591, 2021 | 48 | 2021 |
Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection H Alachkar, M Mutonga, T Kato, S Kalluri, Y Kakuta, M Uemura, ... BMC nephrology 17, 1-9, 2016 | 34 | 2016 |
Profiling of T cell repertoire in SARS-CoV-2-infected COVID-19 patients between mild disease and pneumonia CM Chang, PH Feng, TH Wu, H Alachkar, KY Lee, WC Chang Journal of clinical immunology 41 (6), 1131-1145, 2021 | 32 | 2021 |
Characterization of mutations in the mitochondrial encoded electron transport chain complexes in acute myeloid leukemia S Wu, M Akhtari, H Alachkar Scientific Reports 8 (1), 13301, 2018 | 32 | 2018 |
SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells T Vougiouklakis, K Sone, V Saloura, HS Cho, T Suzuki, N Dohmae, ... Oncotarget 6 (41), 43162, 2015 | 31 | 2015 |
T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia H Alachkar, M Mutonga, G Malnassy, JH Park, N Fulton, A Woods, L Meng, ... Oncotarget 6 (32), 33410, 2015 | 29 | 2015 |
Midostaurin reduces regulatory T cells markers in acute myeloid leukemia L Gutierrez, M Jang, T Zhang, M Akhtari, H Alachkar Scientific Reports 8 (1), 17544, 2018 | 26 | 2018 |
Clinical and preclinical characterization of CD99 isoforms in acute myeloid leukemia VP Vaikari, Y Du, S Wu, T Zhang, K Metzeler, AMN Batcha, T Herold, ... Haematologica 105 (4), 999, 2020 | 23 | 2020 |