Platensimycin is a selective FabF inhibitor with potent antibiotic properties J Wang, SM Soisson, K Young, W Shoop, S Kodali, A Galgoci, R Painter, ... Nature 441 (7091), 358-361, 2006 | 1007 | 2006 |
Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 574 | 2021 |
Natural acetogenins from Annonaceae, synthesis and mechanisms of action MC Zafra-Polo, B Figadère, T Gallardo, JR Tormo, D Cortes Phytochemistry 48 (7), 1087-1117, 1998 | 292 | 1998 |
Current approaches to exploit actinomycetes as a source of novel natural products O Genilloud, I González, O Salazar, J Martín, JR Tormo, F Vicente Journal of Industrial Microbiology and Biotechnology 38 (3), 375-389, 2011 | 275 | 2011 |
Discovery of FabH/FabF inhibitors from natural products K Young, H Jayasuriya, JG Ondeyka, K Herath, C Zhang, S Kodali, ... Antimicrobial agents and chemotherapy 50 (2), 519-526, 2006 | 256 | 2006 |
A New Approach to Drug Discovery: High-Throughput Screening of Microbial Natural Extracts against Aspergillus fumigatus Using Resazurin MC Monteiro, M de la Cruz, J Cantizani, C Moreno, JR Tormo, E Mellado, ... Journal of biomolecular screening 17 (4), 542-549, 2012 | 170 | 2012 |
Enhancement of antibiotic and secondary metabolite detection from filamentous fungi by growth on nutritional arrays GF Bills, G Platas, A Fillola, MR Jiménez, J Collado, F Vicente, J Martín, ... Journal of applied microbiology 104 (6), 1644-1658, 2008 | 166 | 2008 |
Sponge-derived Kocuria and Micrococcus spp. as sources of the new thiazolyl peptide antibiotic kocurin S Palomo, I González, M De la Cruz, J Martín, JR Tormo, M Anderson, ... Marine drugs 11 (4), 1071-1086, 2013 | 131 | 2013 |
Discovery of Bacterial Fatty Acid Synthase Inhibitors from a Phoma Species as Antimicrobial Agents Using a New Antisense-Based Strategy JG Ondeyka, DL Zink, K Young, R Painter, S Kodali, A Galgoci, J Collado, ... Journal of natural products 69 (3), 377-380, 2006 | 101 | 2006 |
Kocurin, the true structure of PM181104, an anti-methicillin-resistant Staphylococcus aureus (MRSA) thiazolyl peptide from the marine-derived bacterium Kocuria palustris J Martín, DS Sousa, G Crespo, S Palomo, I González, JR Tormo, ... Marine Drugs 11 (2), 387-398, 2013 | 84 | 2013 |
Specific interactions of monotetrahydrofuranic annonaceous acetogenins as inhibitors of mitochondrial complex I JR Tormo, T Gallardo, R Aragón, D Cortes, E Estornell Chemico-Biological Interactions 122 (3), 171-183, 1999 | 78 | 1999 |
Bacterial diversity from benthic mats of Antarctic lakes as a source of new bioactive metabolites JL Rojas, J Martín, JR Tormo, F Vicente, M Brunati, I Ciciliato, D Losi, ... Marine Genomics 2 (1), 33-41, 2009 | 66 | 2009 |
Discovery of the parnafungins, antifungal metabolites that inhibit mRNA polyadenylation, from the Fusarium larvarum complex and other Hypocrealean fungi GF Bills, G Platas, DP Overy, J Collado, A Fillola, MR Jiménez, J Martín, ... Mycologia 101 (4), 449-472, 2009 | 64 | 2009 |
Multicomponent analysis of the differential induction of secondary metabolite profiles in fungal endophytes V González-Menéndez, M Pérez-Bonilla, I Pérez-Victoria, J Martín, ... Molecules 21 (2), 234, 2016 | 61 | 2016 |
Distribution of the antifungal agents sordarins across filamentous fungi F Vicente, A Basilio, G Platas, J Collado, GF Bills, AG Del Val, J Martín, ... Mycological research 113 (6-7), 754-770, 2009 | 59 | 2009 |
Rollimembrin, a novel acetogenin inhibitor of mammalian mitochondrial complex I MC GonzÁlez, JR Tormo, A Bermejo, MC Zafra-Polo, E Estornell, ... Bioorganic & Medicinal Chemistry Letters 7 (9), 1113-1118, 1997 | 59 | 1997 |
Kinetic characterization of mitochondrial complex I inhibitors using annonaceous acetogenins JR Tormo, MC González, D Cortes, E Estornell Archives of biochemistry and biophysics 369 (1), 119-126, 1999 | 56 | 1999 |
Annonaceous acetogenins as inhibitors of mitochondrial complex I JR Tormo, T Gallardo, MC González, A Bermejo, N Cabedo, I Andreu, ... Current Topics in Phytochemistry 2, 69-90, 1999 | 56 | 1999 |
Discovery of New Compounds Active against Plasmodium falciparum by High Throughput Screening of Microbial Natural Products G Pérez-Moreno, J Cantizani, P Sánchez-Carrasco, LM Ruiz-Pérez, ... PloS one 11 (1), e0145812, 2016 | 46 | 2016 |
γ-Lactone-functionalized antitumoral acetogenins are the most potent inhibitors of mitochondrial complex I JR Tormo, E Estornell, T Gallardo, MC González, A Cavé, S Granell, ... Bioorganic & medicinal chemistry letters 11 (5), 681-684, 2001 | 45 | 2001 |