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Joel Kaye
Joel Kaye
Pharmacology Project Leader, Teva Pharmaceutical Industries Ltd
Bestätigte E-Mail-Adresse bei teva.co.il
Titel
Zitiert von
Zitiert von
Jahr
Predominance of the autoimmune response to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis: reactivity to the extracellular domain of MOG is directed against …
NK De Rosbo, M Hoffman, I Mendel, I Yust, J Kaye, R Bakimer, S Flechter, ...
European journal of immunology 27 (11), 3059-3069, 1997
2211997
Vaccination for neuroprotection in the mouse optic nerve: implications for optic neuropathies
J Fisher, H Levkovitch-Verbin, H Schori, E Yoles, O Butovsky, JF Kaye, ...
Journal of Neuroscience 21 (1), 136-142, 2001
2182001
Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies
E Montero, G Nussbaum, JF Kaye, R Perez, A Lage, A Ben-Nun, ...
Journal of autoimmunity 23 (1), 1-7, 2004
1582004
Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor
J Kaye, V Piryatinsky, T Birnberg, T Hingaly, E Raymond, R Kashi, ...
Proceedings of the National Academy of Sciences 113 (41), E6145-E6152, 2016
1232016
Treatment of Crohn's disease with laquinimod
N Tarcic, A Haviv, E Blaugrund, J Kaye
US Patent 8,598,203, 2013
1042013
The myelin-associated oligodendrocytic basic protein region MOBP15–36 encompasses the immunodominant major encephalitogenic epitope (s) for SJL/J mice and predicted epitope (s …
NK De Rosbo, JF Kaye, M Eisenstein, I Mendel, R Hoeftberger, ...
The Journal of Immunology 173 (2), 1426-1435, 2004
762004
Rhesus monkeys are highly susceptible to experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein: characterisation of immunodominant T-and B …
NK de Rosbo, HPM Brok, J Bauer, JF Kaye, B A’t Hart, A Ben-Nun
Journal of neuroimmunology 110 (1-2), 83-96, 2000
692000
Anatomy of T cell autoimmunity to myelin oligodendrocyte glycoprotein (MOG): Prime role of MOG44F in selection and control of MOG‐reactive T cells in H‐2b mice
A Ben‐Nun, NK de Rosbo, N Kaushansky, M Eisenstein, L Cohen, ...
European journal of immunology 36 (2), 478-493, 2006
492006
The central nervous sytem-specific myelin oligodendrocytic basic protein (MOBP) is encephalitogenic and a potential target antigen in multiple sclerosis (MS)
JF Kaye, NK de Rosbo, I Mendel, S Flechter, M Hoffman, I Yust, ...
Journal of Neuroimmunology 102 (2), 189-198, 2000
492000
Kerlero de Rosbo
JF Kaye
N., Mendel, I., Flechter, S., Hoffman, M., Yust, I., Ben-Nun, A, 189-198, 2000
482000
Mice overexpressing Bcl-2 in their neurons are resistant to myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE)
D Offen, JF Kaye, O Bernard, D Merims, CI Coire, H Panet, E Melamed, ...
Journal of Molecular Neuroscience 15, 167-176, 2000
372000
Impact of glatiramer acetate on B cell-mediated pathogenesis of multiple sclerosis
S Kuerten, LJ Jackson, J Kaye, TL Vollmer
CNS drugs 32 (11), 1039-1051, 2018
332018
Aryl hydrocarbon receptor activation in astrocytes by laquinimod ameliorates autoimmune inflammation in the CNS
V Rothhammer, JE Kenison, Z Li, E Tjon, MC Takenaka, CC Chao, ...
Neurology: Neuroimmunology & Neuroinflammation 8 (2), e946, 2021
282021
Effects of surface finish
JT Burwell, J Kaye, DW Van Nymegen, DA Morgan
American Society of Mechanical Engineers 8 (2), A49-A58, 1941
261941
Directed evolution of a soluble human IL-17A receptor for the inhibition of psoriasis plaque formation in a mouse model
M Zaretsky, R Etzyoni, J Kaye, L Sklair-Tavron, A Aharoni
Chemistry & Biology 20 (2), 202-211, 2013
252013
A novel cytidine analog, RX-3117, shows potent efficacy in xenograft models, even in tumors that are resistant to gemcitabine
MY Yang, YB Lee, CH Ahn, J Kaye, T Fine, R Kashi, O Ohne, K Smid, ...
Anticancer research 34 (12), 6951-6959, 2014
222014
Treatment of multiple sclerosis with combination of laquinimod and dimethyl fumarate
JF Kaye
US Patent App. 13/800,047, 2013
222013
Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate
J Kaye, E Blaugrund, N Tarcic
US Patent 8,501,766, 2013
222013
AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling
R Ferrarotto, V Mishra, E Herz, A Yaacov, O Solomon, R Rauch, ...
Cell Death & Disease 13 (8), 678, 2022
192022
Laquinimod ameliorates secondary brain inflammation
J Nedelcu, C Reinbach, P Riedler, M Brendel, A Rominger, J Kaye, ...
Neurobiology of disease 134, 104675, 2020
182020
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