| Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease ML Agostini, EL Andres, AC Sims, RL Graham, TP Sheahan, X Lu, ... MBio 9 (2), 2018 | 1395 | 2018 |
| Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics EC Smith, H Blanc, M Vignuzzi, MR Denison PLoS Pathog 9 (8), e1003565, 2013 | 475 | 2013 |
| Homology-based identification of a mutation in the coronavirus RNA-dependent RNA polymerase that confers resistance to multiple mutagens NR Sexton, EC Smith, H Blanc, M Vignuzzi, OB Peersen, MR Denison Journal of virology 90 (16), 7415-7428, 2016 | 222 | 2016 |
| Viral entry mechanisms: the increasing diversity of paramyxovirus entry EC Smith, A Popa, A Chang, C Masante, RE Dutch The FEBS journal 276 (24), 7217-7227, 2009 | 217 | 2009 |
| Thinking outside the triangle: replication fidelity of the largest RNA viruses EC Smith, NR Sexton, MR Denison Annual Review of Virology 1, 2014 | 142 | 2014 |
| Coronaviruses as DNA wannabes: a new model for the regulation of RNA virus replication fidelity EC Smith, MR Denison PLoS Pathog 9 (12), e1003760, 2013 | 129 | 2013 |
| Inhibition of polyamine biosynthesis is a broad-spectrum strategy against RNA viruses BC Mounce, T Cesaro, G Moratorio, PJ Hooikaas, A Yakovleva, ... Journal of virology 90 (21), 9683-9692, 2016 | 90 | 2016 |
| Mutations in Coronavirus Nonstructural Protein 10 Decrease Virus Replication Fidelity EC Smith, JB Case, H Blanc, O Isakov, N Shomron, M Vignuzzi, ... Journal of virology 89 (12), 6418-6426, 2015 | 77 | 2015 |
| Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF) C Zhao, EC Smith, SW Whiteheart Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (1), 159-171, 2012 | 68 | 2012 |
| Coronaviruses Induce Entry-Independent, Continuous Macropinocytosis MC Freeman, CT Peek, MM Becker, EC Smith, MR Denison mBio 5 (4), e01340-14, 2014 | 63 | 2014 |
| Implications of altered replication fidelity on the evolution and pathogenesis of coronaviruses EC Smith, MR Denison Current opinion in virology 2 (5), 519-524, 2012 | 63 | 2012 |
| Proofreading-deficient coronaviruses adapt for increased fitness over long-term passage without reversion of exoribonuclease-inactivating mutations KW Graepel, X Lu, JB Case, NR Sexton, EC Smith, MR Denison MBio 8 (6), 2017 | 60 | 2017 |
| Murine hepatitis virus nsp14 exoribonuclease activity is required for resistance to innate immunity JB Case, Y Li, R Elliott, X Lu, KW Graepel, NR Sexton, EC Smith, ... Journal of Virology 92 (1), 2018 | 55 | 2018 |
| In situ tagged nsp15 reveals interactions with coronavirus replication/transcription complex-associated proteins J Athmer, AR Fehr, M Grunewald, EC Smith, MR Denison, S Perlman MBio 8 (1), e02320-16, 2017 | 53 | 2017 |
| Trimeric Transmembrane Domain Interactions in Paramyxovirus Fusion Proteins ROLES IN PROTEIN FOLDING, STABILITY, AND FUNCTION EC Smith, SE Smith, JR Carter, SR Webb, KM Gibson, LM Hellman, ... Journal of Biological Chemistry 288 (50), 35726-35735, 2013 | 44 | 2013 |
| The not-so-infinite malleability of RNA viruses: Viral and cellular determinants of RNA virus mutation rates EC Smith PLoS pathogens 13 (4), e1006254, 2017 | 42 | 2017 |
| Serotonin Receptor Agonist 5-Nonyloxytryptamine Alters the Kinetics of Reovirus Cell Entry BA Mainou, AW Ashbrook, EC Smith, DC Dorset, MR Denison, ... Journal of virology 89 (17), 8701-8712, 2015 | 40 | 2015 |
| Beyond anchoring: the expanding role of the hendra virus fusion protein transmembrane domain in protein folding, stability, and function EC Smith, MR Culler, LM Hellman, MG Fried, TP Creamer, RE Dutch Journal of virology 86 (6), 3003-3013, 2012 | 38 | 2012 |
| The actin cytoskeleton inhibits pore expansion during PIV5 fusion protein-promoted cell–cell fusion MA Wurth, RM Schowalter, EC Smith, CL Moncman, RE Dutch, ... Virology 404 (1), 117-126, 2010 | 36 | 2010 |
| Differential rates of protein folding and cellular trafficking for the Hendra virus F and G proteins: implications for FG complex formation SD Whitman, EC Smith, RE Dutch Journal of virology 83 (17), 8998-9001, 2009 | 30 | 2009 |
