In Silico Classifiers for the Assessment of Drug Proarrhythmicity J Llopis-Lorente, J Gomis-Tena, J Cano, L Romero, J Saiz, B Trenor Journal of Chemical Information and Modeling 60 (10), 5172-5187, 2020 | 26 | 2020 |
Considering population variability of electrophysiological models improves the in silico assessment of drug-induced torsadogenic risk J Llopis-Lorente, B Trenor, J Saiz Computer Methods and Programs in Biomedicine 221, 106934, 2022 | 9 | 2022 |
Application of machine learning to improve the efficiency of electrophysiological simulations used for the prediction of drug-induced ventricular arrhythmia P Rodríguez-Belenguer, K Kopańska, J Llopis-Lorente, B Trenor, J Saiz, ... Computer Methods and Programs in Biomedicine 230, 107345, 2023 | 2 | 2023 |
Uncertainty assessment of proarrhythmia predictions derived from multi-level in silico models K Kopańska, P Rodríguez-Belenguer, J Llopis-Lorente, B Trenor, J Saiz, ... Archives of Toxicology 97 (10), 2721-2740, 2023 | 1 | 2023 |
Omecamtiv Mecarbil Improves Contraction Behaviour in a 3D Electromechanical Tissue Model of Heart Failure I van Herck, MT Mora, J Llopis-Lorente, H Finsberg, C Daversin-Catty, ... 2022 Computing in Cardiology (CinC) 498, 1-4, 2022 | 1 | 2022 |
Impact of Epicardial Adipose Tissue on Infarct Size and Left Ventricular Systolic Function in Patients with Anterior ST-Segment Elevation Myocardial Infarction J Gavara, H Merenciano-Gonzalez, J Llopis-Lorente, T Molina-Garcia, ... Diagnostics 14 (4), 368, 2024 | | 2024 |
The paradox of the association between epicardial adipose tissue, infarct size and left ventricular remodelling after ST-segment elevation myocardial infarction: a CMR study H Merenciano Gonzalez, J Gavara, V Marcos-Garces, T Molina-Garcia, ... European Heart Journal 44 (Supplement_2), ehad655. 1398, 2023 | | 2023 |
Combining pharmacokinetic and electrophysiological models for early prediction of drug-induced arrhythmogenicity J Llopis-Lorente, S Baroudi, K Koloskoff, MT Mora, M Basset, L Romero, ... Computer Methods and Programs in Biomedicine, 107860, 2023 | | 2023 |
A Causal Discovery Approach to Streamline Ionic Currents Selection to Improve Drug-Induced TdP Risk Assessment S Al-Ali, J Llopis-Lorente, MT Mora, M Sermesant, B Trénor, I Balelli 2023 Computing in Cardiology (CinC) 50, 1-4, 2023 | | 2023 |
BS-452759-3 A NOVEL IN SILICO PHARMACOKINETIC/ELECTROPHYSIOLOGICAL MODELING FRAMEWORK TO ASSESS THE INFLUENCE OF SEX AND RENAL STATUS ON DRUG-INDUCED ARRHYTHMOGENICITY J Llopis-Lorente, S Baroudi, K Koloskoff, MT Mora, L Romero, S Benito, ... Heart Rhythm 20 (5), S67-S68, 2023 | | 2023 |
Effect of incorporating inter-individual variability in the in silico prediction of drug-induced arrhythmogenic risk J Llopis-Lorente, J Saiz, B Trenor JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS 117, 2022 | | 2022 |
Prediction of Drug-Induced Arrhythmogenic Risk Using In Silico Populations of Models J Llopis-Lorente, B Trénor, J Saiz 2021 Computing in Cardiology (CinC) 48, 1-4, 2021 | | 2021 |
Estimation of uncertainty in multi-level in silico models predicting biomarkers of drug-induced proarrhythmic risk K Kopanska, JC Gómez-Tamayo, J Llopis-Lorente, BA Trenor-Gomis, ... Toxicology Letters 350, S64-S65, 2021 | | 2021 |
In silico study of drug effects on human non-failing and failing cardiomyocytes JL Lorente, JGT Dolz, LR Pérez, FJS Rodríguez, BT Gomis Journal of Pharmacological and Toxicological Methods 111, 107045, 2021 | | 2021 |
Use of the comprehensive in vitro proarrhythmia assay and in silico modeling to investigate the safety profile of bisphenol analogues R Jaimes, D McCullough, L Swift, M Reilly, M Burke, JL Lorente, ... Journal of Pharmacological and Toxicological Methods 105, 106806, 2020 | | 2020 |
In silico classifier for early screening of drug-induced torsadogenic risk JL Lorente, JC García, JGT Dolz, LR Pérez, FS Carreras, MP Maeso, ... Journal of Pharmacological and Toxicological Methods 105, 106801, 2020 | | 2020 |
Tx, TqNet and Ttriang Values J Llopis Lorente, J Gomis-Tena Dolz, J Cano García, L Romero Pérez, ... Universitat Politècnica de València, 2020 | | 2020 |
Análisis comparativo del efecto farmacológico en células ventriculares sanas y con insuficiencia cardíaca mediante métodos de modelado y simulación J Llopis Lorente Universitat Politècnica de València, 2018 | | 2018 |
Estudio in-silico de la cardiotoxicidad inducida por fármacos en células ventriculares sanas y con insuficiencia cardíaca JL Lorente, J Cano, JG Tena, L Romero, BAT Gomis, J Saiz Libro de Actas del XXXVI Congreso Anual de la Sociedad Española de …, 2018 | | 2018 |