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Riley E Perszyk
Riley E Perszyk
Verified email at emory.edu
Title
Cited by
Cited by
Year
Structure, function, and allosteric modulation of NMDA receptors
KB Hansen, F Yi, RE Perszyk, H Furukawa, LP Wollmuth, AJ Gibb, ...
Journal of General Physiology 150 (8), 1081-1105, 2018
4822018
Structure, function, and pharmacology of glutamate receptor ion channels
KB Hansen, LP Wollmuth, D Bowie, H Furukawa, FS Menniti, ...
Pharmacological Reviews 73 (4), 298-487, 2021
2742021
NMDA receptors in the central nervous system
KB Hansen, F Yi, RE Perszyk, FS Menniti, SF Traynelis
NMDA Receptors, 1-80, 2017
1532017
GluN2D-containing N-methyl-d-aspartate receptors mediate synaptic transmission in hippocampal interneurons and regulate interneuron activity
RE Perszyk, JO DiRaddo, KL Strong, CM Low, KK Ogden, A Khatri, ...
Molecular pharmacology 90 (6), 689-702, 2016
932016
Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors
KB Hansen, N Tajima, R Risgaard, RE Perszyk, L Jørgensen, KM Vance, ...
Molecular pharmacology 84 (1), 114-127, 2013
852013
An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups
R Perszyk, BM Katzman, H Kusumoto, SA Kell, MP Epplin, YA Tahirovic, ...
Elife 7, e34711, 2018
382018
Biased modulators of NMDA receptors control channel opening and ion selectivity
RE Perszyk, SA Swanger, C Shelley, A Khatri, G Fernandez-Cuervo, ...
Nature chemical biology 16 (2), 188-196, 2020
312020
Adolescent cocaine exposure simplifies orbitofrontal cortical dendritic arbors
LM DePoy, RE Perszyk, KS Zimmermann, AJ Koleske, SL Gourley
Frontiers in pharmacology 5, 228, 2014
262014
Hodgkin–Huxley–Katz Prize Lecture: Genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif
RE Perszyk, SJ Myers, H Yuan, AJ Gibb, H Furukawa, AI Sobolevsky, ...
The Journal of physiology 598 (15), 3071-3083, 2020
222020
A novel class of negative allosteric modulators of NMDA receptor function
BM Katzman, RE Perszyk, H Yuan, YA Tahirovic, AE Sotimehin, ...
Bioorganic & medicinal chemistry letters 25 (23), 5583-5588, 2015
202015
Three-dimensional missense tolerance ratio analysis
RE Perszyk, AS Kristensen, P Lyuboslavsky, SF Traynelis
Genome Research 31 (8), 1447-1461, 2021
182021
The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca2+ Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors
RE Perszyk, Z Zheng, TG Banke, J Zhang, L Xie, MJ McDaniel, ...
Molecular Pharmacology 99 (5), 399-411, 2021
102021
Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors
KL Strong, MP Epplin, KK Ogden, PB Burger, TM Kaiser, TJ Wilding, ...
ACS chemical neuroscience 12 (1), 79-98, 2020
102020
Opportunities for precision treatment of GRIN2A and GRIN2B gain-of-function variants in triheteromeric NMDA receptors
W Han, H Yuan, JP Allen, S Kim, GH Shaulsky, RE Perszyk, SF Traynelis, ...
Journal of Pharmacology and Experimental Therapeutics, 2022
72022
Automated intracellular pharmacological electrophysiology for ligand-gated ionotropic receptor and pharmacology screening
RE Perszyk, MC Yip, OL McConnell, ET Wang, A Jenkins, SF Traynelis, ...
Molecular Pharmacology 100 (1), 73-82, 2021
52021
The GluN2A subunit of the NMDA receptor modulates the rate of functional maturation in parvalbumin-positive interneurons
CR Camp, L Shapiro, A Vlachos, RE Perszyk, N Shariatzadeh, J White, ...
bioRxiv, 2021
2021
Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif (vol 598, pg 3071, 2020)
RE Perszyk, SJ Myers, H Yuan, AJ Gibb, H Furukawa, A Sobolevsky, ...
JOURNAL OF PHYSIOLOGY-LONDON 598 (21), 4995-4995, 2020
2020
Channel Open Probability Controls Allosteric Modulation of Potency and Efficacy
RE Perszyk, KK Ogden, KL Strong, DC Liotta, SF Traynelis
Biophysical Journal 112 (3), 420a-421a, 2017
2017
A conserved Asparagine Between Loops A and E of Anion Ligand-Gated Channels is Critical for Gaba (A) Receptor Function
REA Perszyk, CA Wiliams, A Jenkins
Biophysical Journal 100 (3), 271a, 2011
2011
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Articles 1–19