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Zeng-jie Yang
Zeng-jie Yang
Fox Chase Cancer Center
Verified email at fccc.edu
Title
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Cited by
Year
Subtypes of medulloblastoma have distinct developmental origins
P Gibson, Y Tong, G Robinson, MC Thompson, DS Currle, C Eden, ...
Nature 468 (7327), 1095-1099, 2010
9262010
Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells
ZJ Yang, T Ellis, SL Markant, TA Read, JD Kessler, M Bourboulas, ...
Cancer cell 14 (2), 135-145, 2008
7652008
Hit'em where they live: targeting the cancer stem cell niche
ZJ Yang, RJ Wechsler-Reya
Cancer cell 11 (1), 3-5, 2007
1832007
A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity
P Li, F Du, LW Yuelling, T Lin, RE Muradimova, R Tricarico, J Wang, ...
Nature neuroscience 16 (12), 1737-1744, 2013
1192013
Single-cell transcriptomics in medulloblastoma reveals tumor-initiating progenitors and oncogenic cascades during tumorigenesis and relapse
L Zhang, X He, X Liu, F Zhang, LF Huang, AS Potter, L Xu, W Zhou, ...
Cancer Cell 36 (3), 302-318. e7, 2019
1092019
N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma
JD Kessler, H Hasegawa, SN Brun, BA Emmenegger, ZJ Yang, JW Dutton, ...
Genes & development 23 (2), 157-170, 2009
812009
Statins synergize with hedgehog pathway inhibitors for treatment of medulloblastoma
RE Gordon, L Zhang, S Peri, YM Kuo, F Du, BL Egleston, JMY Ng, ...
Clinical Cancer Research 24 (6), 1375-1388, 2018
512018
Astrocytes promote medulloblastoma progression through hedgehog secretion
Y Liu, LW Yuelling, Y Wang, F Du, RE Gordon, JA O'Brien, JMY Ng, ...
Cancer research 77 (23), 6692-6703, 2017
502017
Group I Paks as therapeutic targets in NF2-deficient meningioma
HY Chow, B Dong, SG Duron, DA Campbell, CC Ong, KP Hoeflich, ...
Oncotarget 6 (4), 1981, 2015
462015
NeuroD1 dictates tumor cell differentiation in medulloblastoma
Y Cheng, S Liao, G Xu, J Hu, D Guo, F Du, A Contreras, KQ Cai, S Peri, ...
Cell reports 31 (12), 2020
362020
Nestin mediates hedgehog pathway tumorigenesis
P Li, EH Lee, F Du, RE Gordon, LW Yuelling, Y Liu, JMY Ng, H Zhang, ...
Cancer research 76 (18), 5573-5583, 2016
322016
Sustained hedgehog signaling in medulloblastoma tumoroids is attributed to stromal astrocytes and astrocyte-derived extracellular matrix
Y Cheng, J Franco-Barraza, Y Wang, C Zheng, L Zhang, Y Qu, Y Long, ...
Laboratory Investigation 100 (9), 1208-1222, 2020
212020
Novel strategy to study gene expression and function in developing cerebellar granule cells
Z Yang, VJ Appleby, B Coyle, WI Chan, M Tahmaseb, PM Wigmore, ...
Journal of neuroscience methods 132 (2), 149-160, 2004
212004
Tumor cells generate astrocyte-like cells that contribute to SHH-driven medulloblastoma relapse
D Guo, Y Wang, Y Cheng, S Liao, J Hu, F Du, G Xu, Y Liu, KQ Cai, ...
Journal of Experimental Medicine 218 (9), e20202350, 2021
202021
Design, Synthesis, and Structure–Activity Relationship of Tetrahydropyrido[4,3-d]pyrimidine Derivatives as Potent Smoothened Antagonists with in Vivo Activity
W Lu, Y Liu, H Ma, J Zheng, S Tian, Z Sun, L Luo, J Li, H Zhang, ZJ Yang, ...
ACS Chemical Neuroscience 8 (9), 1980-1994, 2017
202017
NGL-2 is a new partner of PAR complex in axon differentiation
G Xu, R Wang, Z Wang, Q Lei, Z Yu, C Liu, P Li, Z Yang, X Cheng, G Li, ...
Journal of Neuroscience 35 (18), 7153-7164, 2015
202015
Statins repress hedgehog signaling in medulloblastoma with no bone toxicities
Q Fan, T Gong, C Zheng, JMY Ng, J Chen, C Myers, H Hensley, T Curran, ...
Oncogene 40 (12), 2258-2272, 2021
112021
Leukotriene synthesis is critical for medulloblastoma progression
F Du, L Yuelling, EH Lee, Y Wang, S Liao, Y Cheng, L Zhang, C Zheng, ...
Clinical Cancer Research 25 (21), 6475-6486, 2019
112019
grp75 protects cells from injuries caused by glucose deprivation
DH Zheng, J Zuo, ZJ Yang, BL Xia, XN Zhang
Yi Chuan xue bao= Acta Genetica Sinica 27 (8), 666-671, 2000
112000
Nestin is required for spindle assembly and cell-cycle progression in Glioblastoma cells
Q Wang, H Wu, J Hu, H Fu, Y Qu, Y Yang, KQ Cai, A Efimov, M Wu, T Yen, ...
Molecular Cancer Research 19 (10), 1651-1665, 2021
102021
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