| The Wnt inhibitor sclerostin is up-regulated by mechanical unloading in osteocytes in vitro JM Spatz, MN Wein, JH Gooi, Y Qu, JL Garr, S Liu, KJ Barry, Y Uda, F Lai, ... Journal of Biological Chemistry 290 (27), 16744-16758, 2015 | 290 | 2015 |
| Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading JM Spatz, R Ellman, AM Cloutier, L Louis, M van Vliet, LJ Suva, D Dwyer, ... Journal of Bone and Mineral Research 28 (4), 865-874, 2013 | 168 | 2013 |
| HDAC5 controls MEF2C‐driven sclerostin expression in osteocytes MN Wein, J Spatz, S Nishimori, J Doench, D Root, P Babij, K Nagano, ... Journal of bone and mineral research 30 (3), 400-411, 2015 | 158 | 2015 |
| Serum sclerostin increases in healthy adult men during bed rest JM Spatz, EE Fields, EW Yu, PD Pajevic, ML Bouxsein, JD Sibonga, ... The Journal of Clinical Endocrinology & Metabolism 97 (9), E1736-E1740, 2012 | 157 | 2012 |
| Bone metabolism and renal stone risk during International Space Station missions SM Smith, M Heer, LC Shackelford, JD Sibonga, J Spatz, RA Pietrzyk, ... Bone 81, 712-720, 2015 | 155 | 2015 |
| Osteocyte‐secreted Wnt signaling inhibitor sclerostin contributes to beige adipogenesis in peripheral fat depots K Fulzele, F Lai, C Dedic, V Saini, Y Uda, C Shi, P Tuck, JL Aronson, X Liu, ... Journal of Bone and Mineral Research 32 (2), 373-384, 2017 | 101 | 2017 |
| Partial reductions in mechanical loading yield proportional changes in bone density, bone architecture, and muscle mass R Ellman, J Spatz, A Cloutier, R Palme, BA Christiansen, ML Bouxsein Journal of Bone and Mineral Research 28 (4), 875-885, 2013 | 100 | 2013 |
| Amphiregulin-EGFR signaling mediates the migration of bone marrow mesenchymal progenitors toward PTH-stimulated osteoblasts and osteocytes J Zhu, VA Siclari, F Liu, JM Spatz, A Chandra, P Divieti Pajevic, L Qin PloS one 7 (12), e50099, 2012 | 51 | 2012 |
| Combined effects of botulinum toxin injection and hind limb unloading on bone and muscle R Ellman, DJ Grasso, M Van Vliet, DJ Brooks, JM Spatz, C Conlon, ... Calcified tissue international 94, 327-337, 2014 | 48 | 2014 |
| Single-cell RNA sequencing and spatial transcriptomics reveal cancer-associated fibroblasts in glioblastoma with protumoral effects S Jain, JW Rick, RS Joshi, A Beniwal, J Spatz, S Gill, ACC Chang, ... The Journal of clinical investigation 133 (5), 2023 | 45 | 2023 |
| Precision annotation of digital samples in NCBI’s gene expression omnibus D Hadley, J Pan, O El-Sayed, J Aljabban, I Aljabban, TD Azad, ... Scientific data 4 (1), 1-11, 2017 | 43 | 2017 |
| Spaceflight and hind limb unloading induce similar changes in electrical impedance characteristics of mouse gastrocnemius muscle M Sung, J Li, AJ Spieker, J Spatz, R Ellman, VL Ferguson, TA Bateman, ... Journal of musculoskeletal & neuronal interactions 13 (4), 405, 2013 | 39 | 2013 |
| Effects of long-duration spaceflight, microgravity, and radiation on the neuromuscular, sensorimotor, and skeletal systems RD Carpenter, TF Lang, SA Bloomfield, JJ Bloomberg, S Judex, JH Keyak, ... J. Cosmol 12, 3778-3780, 2010 | 36 | 2010 |
| Osteocyte biology and space flight PD Pajevic, JM Spatz, J Garr, C Adamson, L Misener Current biotechnology 2 (3), 179, 2013 | 30 | 2013 |
| Broad-spectrum CRISPR-mediated inhibition of SARS-CoV-2 variants and endemic coronaviruses in vitro L Zeng, Y Liu, XH Nguyenla, TR Abbott, M Han, Y Zhu, A Chemparathy, ... Nature communications 13 (1), 2766, 2022 | 24 | 2022 |
| Human immune system adaptations to simulated microgravity revealed by single-cell mass cytometry JM Spatz, MH Fulford, A Tsai, D Gaudilliere, J Hedou, E Ganio, M Angst, ... Scientific reports 11 (1), 11872, 2021 | 20 | 2021 |
| AG protein–coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23 Q He, LT Shumate, J Matthias, C Aydin, MN Wein, JM Spatz, R Goetz, ... JCI insight 4 (17), 2019 | 19 | 2019 |
| Sequential stem cell–kidney transplantation in Schimke immuno-osseous dysplasia A Bertaina, PC Grimm, K Weinberg, R Parkman, KM Kristovich, ... New England Journal of Medicine 386 (24), 2295-2302, 2022 | 18 | 2022 |
| Interfacility neurosurgical transfers: an analysis of nontraumatic inpatient and emergency department transfers with implications for improvements in care MM Safaee, RA Morshed, J Spatz, S Sankaran, MS Berger, MK Aghi Journal of Neurosurgery 131 (1), 281-289, 2018 | 18 | 2018 |
| Treatment with a soluble bone morphogenetic protein type 1A receptor (BMPR1A) fusion protein increases bone mass and bone formation in mice subjected to hindlimb unloading FC Ko, M Van Vliet, R Ellman, D Grasso, DJ Brooks, JM Spatz, C Conlon, ... Journal of Bone and Mineral Research Plus 1 (2), 66-72, 2017 | 15 | 2017 |
Paola Divieti PajevicAssociate Professor of Translational Dental Medicine, Boston UniversityVerified email at bu.edu
