Follow
Jan Mauer, Ph.D.
Jan Mauer, Ph.D.
Lab Head at Novartis Institutes for BioMedical Research (NIBR)
Verified email at novartis.com
Title
Cited by
Cited by
Year
Reversible methylation of m6Am in the 5′ cap controls mRNA stability
J Mauer, X Luo, A Blanjoie, X Jiao, AV Grozhik, DP Patil, B Linder, ...
Nature 541 (7637), 371-375, 2017
9712017
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
J Mauer, B Chaurasia, J Goldau, MC Vogt, J Ruud, KD Nguyen, ...
Nature immunology 15 (5), 423-430, 2014
7412014
Obesity-induced CerS6-dependent C16: 0 ceramide production promotes weight gain and glucose intolerance
SM Turpin, HT Nicholls, DM Willmes, A Mourier, S Brodesser, ...
Cell metabolism 20 (4), 678-686, 2014
6172014
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity
A Kleinridders, D Schenten, AC Könner, BF Belgardt, J Mauer, T Okamura, ...
Cell metabolism 10 (4), 249-259, 2009
5522009
Versatile functions for IL-6 in metabolism and cancer
J Mauer, JL Denson, JC Brüning
Trends in immunology 36 (2), 92-101, 2015
4602015
Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding
MC Vogt, L Paeger, S Hess, SM Steculorum, M Awazawa, B Hampel, ...
Cell 156 (3), 495-509, 2014
3672014
AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue
SM Steculorum, J Ruud, I Karakasilioti, H Backes, LE Ruud, K Timper, ...
Cell 165 (1), 125-138, 2016
2492016
IL-6 regulates M2 polarization and local proliferation of adipose tissue macrophages in obesity
J Braune, U Weyer, C Hobusch, J Mauer, JC Brüning, I Bechmann, ...
The Journal of Immunology 198 (7), 2927-2934, 2017
2422017
Myeloid-cell-derived VEGF maintains brain glucose uptake and limits cognitive impairment in obesity
A Jais, M Solas, H Backes, B Chaurasia, A Kleinridders, S Theurich, ...
Cell 165 (4), 882-895, 2016
2312016
FTO controls reversible m6Am RNA methylation during snRNA biogenesis
J Mauer, M Sindelar, V Despic, T Guez, BR Hawley, JJ Vasseur, ...
Nature chemical biology 15 (4), 340-347, 2019
2202019
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism
BF Belgardt, J Mauer, FT Wunderlich, MB Ernst, M Pal, G Spohn, ...
Proceedings of the National Academy of Sciences 107 (13), 6028-6033, 2010
1912010
Single copy shRNA configuration for ubiquitous gene knockdown in mice
J Seibler, B Küter-Luks, H Kern, S Streu, L Plum, J Mauer, R Kühn, ...
Nucleic acids research 33 (7), e67-e67, 2005
1372005
Hierarchical prediction errors in midbrain and septum during social learning
AO Diaconescu, C Mathys, LAE Weber, L Kasper, J Mauer, KE Stephan
Social cognitive and affective neuroscience 12 (4), 618-634, 2017
1322017
Hepatic Bax inhibitor-1 inhibits IRE1α and protects from obesity-associated insulin resistance and glucose intolerance
B Bailly-Maitre, BF Belgardt, SD Jordan, B Coornaert, MJ von Freyend, ...
Journal of biological chemistry 285 (9), 6198-6207, 2010
1252010
Obesogenic memory can confer long-term increases in adipose tissue but not liver inflammation and insulin resistance after weight loss
J Schmitz, N Evers, M Awazawa, HT Nicholls, HS Brönneke, A Dietrich, ...
Molecular metabolism 5 (5), 328-339, 2016
1242016
Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits
S Hult, R Soylu, T Björklund, BF Belgardt, J Mauer, JC Brüning, D Kirik, ...
Cell metabolism 13 (4), 428-439, 2011
1202011
Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment
CM Wunderlich, PJ Ackermann, AL Ostermann, P Adams-Quack, MC Vogt, ...
Nature communications 9 (1), 1-16, 2018
1182018
FTO, m6Am, and the hypothesis of reversible epitranscriptomic mRNA modifications
J Mauer, SR Jaffrey
FEBS letters 592 (12), 2012-2022, 2018
1172018
Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance
J Mauer, B Chaurasia, L Plum, T Quast, B Hampel, M Blüher, W Kolanus, ...
PLoS genetics 6 (5), e1000938, 2010
1162010
IL-6/Stat3-dependent induction of a distinct, obesity-associated NK cell subpopulation deteriorates energy and glucose homeostasis
S Theurich, E Tsaousidou, R Hanssen, AM Lempradl, J Mauer, K Timper, ...
Cell metabolism 26 (1), 171-184. e6, 2017
1152017
The system can't perform the operation now. Try again later.
Articles 1–20