Safety of human immunisation with a live-attenuated Mycobacterium tuberculosis vaccine: a randomised, double-blind, controlled phase I trial F Spertini, R Audran, R Chakour, O Karoui, V Steiner-Monard, AC Thierry, ... The lancet Respiratory medicine 3 (12), 953-962, 2015 | 175 | 2015 |
Pulmonary but not subcutaneous delivery of BCG vaccine confers protection to tuberculosis-susceptible mice by an interleukin 17–dependent mechanism N Aguilo, S Alvarez-Arguedas, S Uranga, D Marinova, M Monzón, ... The Journal of infectious diseases 213 (5), 831-839, 2016 | 134 | 2016 |
Klebsiella pneumoniae survives within macrophages by avoiding delivery to lysosomes V Cano, C March, JL Insua, N Aguiló, E Llobet, D Moranta, V Regueiro, ... Cellular microbiology 17 (11), 1537-1560, 2015 | 132 | 2015 |
Live-attenuated Mycobacterium tuberculosis vaccine MTBVAC versus BCG in adults and neonates: a randomised controlled, double-blind dose-escalation trial M Tameris, H Mearns, A Penn-Nicholson, Y Gregg, N Bilek, S Mabwe, ... The lancet Respiratory medicine 7 (9), 757-770, 2019 | 117 | 2019 |
Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis N Aguilo, J Gonzalo-Asensio, S Alvarez-Arguedas, D Marinova, ... Nature communications 8 (1), 16085, 2017 | 117 | 2017 |
A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component L Solans, N Aguiló, S Samper, A Pawlik, W Frigui, C Martín, R Brosch, ... Infection and immunity 82 (8), 3446-3456, 2014 | 97 | 2014 |
MTBVAC: attenuating the human pathogen of tuberculosis (TB) toward a promising vaccine against the TB epidemic J Gonzalo-Asensio, D Marinova, C Martin, N Aguilo Frontiers in immunology 8, 296893, 2017 | 91 | 2017 |
New live attenuated tuberculosis vaccine MTBVAC induces trained immunity and confers protection against experimental lethal pneumonia R Tarancón, J Domínguez-Andrés, S Uranga, AV Ferreira, LA Groh, ... PLoS pathogens 16 (4), e1008404, 2020 | 79 | 2020 |
Elucidating sources and roles of granzymes A and B during bacterial infection and sepsis MA Arias, MPJ de Bagües, N Aguilo, S Menao, S Hervas-Stubbs, ... Cell reports 8 (2), 420-429, 2014 | 76 | 2014 |
New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages J Gonzalo-Asensio, I Pérez, N Aguiló, S Uranga, A Picó, C Lampreave, ... PLoS genetics 14 (4), e1007282, 2018 | 74 | 2018 |
MTBVAC vaccine is safe, immunogenic and confers protective efficacy against Mycobacterium tuberculosis in newborn mice N Aguilo, S Uranga, D Marinova, M Monzon, J Badiola, C Martin Tuberculosis 96, 71-74, 2016 | 68 | 2016 |
IL-17-dependent SIgA-mediated protection against nasal Bordetella pertussis infection by live attenuated BPZE1 vaccine L Solans, AS Debrie, L Borkner, N Aguiló, A Thiriard, L Coutte, S Uranga, ... Mucosal immunology 11 (6), 1753-1762, 2018 | 63 | 2018 |
MTBVAC from discovery to clinical trials in tuberculosis-endemic countries D Marinova, J Gonzalo-Asensio, N Aguilo, C Martin Expert review of vaccines 16 (6), 565-576, 2017 | 62 | 2017 |
Update on TB vaccine pipeline C Martin, N Aguilo, D Marinova, J Gonzalo-Asensio Applied Sciences 10 (7), 2632, 2020 | 61 | 2020 |
Cell death induced by cytotoxic CD8+ T cells is immunogenic and primes caspase-3–dependent spread immunity against endogenous tumor antigens P Jaime-Sanchez, I Uranga-Murillo, N Aguilo, SC Khouili, MA Arias, ... Journal for immunotherapy of cancer 8 (1), 2020 | 60 | 2020 |
Stronger induction of trained immunity by mucosal BCG or MTBVAC vaccination compared to standard intradermal vaccination MPM Vierboom, K Dijkman, CC Sombroek, SO Hofman, C Boot, ... Cell Reports Medicine 2 (1), 2021 | 58 | 2021 |
Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis N Aguiló, S Uranga, D Marinova, C Martín, J Pardo Cell death & disease 5 (7), e1343-e1343, 2014 | 58 | 2014 |
Human NK cells activated by EBV+ lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells D Sánchez-Martínez, G Azaceta, A Muntasell, N Aguiló, D Núñez, ... Oncoimmunology 4 (3), e991613, 2015 | 50 | 2015 |
ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question N Aguiló, D Marinova, C Martín, J Pardo Frontiers in cellular and infection microbiology 3, 88, 2013 | 50 | 2013 |
TBVAC2020: advancing tuberculosis vaccines from discovery to clinical development SHE Kaufmann, HM Dockrell, N Drager, MM Ho, H McShane, O Neyrolles, ... Frontiers in immunology 8, 1203, 2017 | 49 | 2017 |