| Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse D Schenk, R Barbour, W Dunn, G Gordon, H Grajeda, T Guido, K Hu, ... nature 400 (6740), 173-177, 1999 | 4572 | 1999 |
| Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein D Games, D Adams, R Alessandrini, R Barbour, P Borthelette, ... Nature 373 (6514), 523-527, 1995 | 3525 | 1995 |
| Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease F Bard, C Cannon, R Barbour, RL Burke, D Games, H Grajeda, T Guido, ... Nature medicine 6 (8), 916-919, 2000 | 2731 | 2000 |
| Pairwise multiple comparison procedures with unequal n’s and/or variances: a Monte Carlo study PA Games, JF Howell Journal of Educational Statistics 1 (2), 113-125, 1976 | 1267 | 1976 |
| BACE knockout mice are healthy despite lacking the primary β-secretase activity in brain: implications for Alzheimer’s disease therapeutics SL Roberds, J Anderson, G Basi, MJ Bienkowski, DG Branstetter, ... Human molecular genetics 10 (12), 1317-1324, 2001 | 982 | 2001 |
| A learning deficit related to age and β-amyloid plaques in a mouse model of Alzheimer's disease G Chen, KS Chen, J Knox, J Inglis, A Bernard, SJ Martin, A Justice, ... Nature 408 (6815), 975-979, 2000 | 937 | 2000 |
| Amyloid precursor protein processing and Aβ42 deposition in a transgenic mouse model of Alzheimer disease K Johnson-Wood, M Lee, R Motter, K Hu, G Gordon, R Barbour, K Khan, ... Proceedings of the National Academy of Sciences 94 (4), 1550-1555, 1997 | 784 | 1997 |
| Effects of α-synuclein immunization in a mouse model of Parkinson’s disease E Masliah, E Rockenstein, A Adame, M Alford, L Crews, M Hashimoto, ... Neuron 46 (6), 857-868, 2005 | 712 | 2005 |
| Imaging of amyloid-β deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy BJ Bacskai, ST Kajdasz, RH Christie, C Carter, D Games, P Seubert, ... Nature medicine 7 (3), 369-372, 2001 | 637 | 2001 |
| Aβ deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse MC Irizarry, F Soriano, M McNamara, KJ Page, D Schenk, D Games, ... Journal of Neuroscience 17 (18), 7053-7059, 1997 | 634 | 1997 |
| Epitope and isotype specificities of antibodies to β-amyloid peptide for protection against Alzheimer's disease-like neuropathology F Bard, R Barbour, C Cannon, R Carretto, M Fox, D Games, T Guido, ... Proceedings of the National Academy of Sciences 100 (4), 2023-2028, 2003 | 565 | 2003 |
| Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β-amyloid precursor protein and Alzheimer’s disease E Masliah, A Sisk, M Mallory, L Mucke, D Schenk, D Games Journal of Neuroscience 16 (18), 5795-5811, 1996 | 503 | 1996 |
| Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease E Masliah, E Rockenstein, M Mante, L Crews, B Spencer, A Adame, ... PloS one 6 (4), e19338, 2011 | 495 | 2011 |
| Multiple comparisons of means PA Games American Educational Research Journal 8 (3), 531-565, 1971 | 478 | 1971 |
| Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease MH Donovan, U Yazdani, RD Norris, D Games, DC German, AJ Eisch Journal of Comparative Neurology 495 (1), 70-83, 2006 | 466 | 2006 |
| Aβ vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease E Masliah, L Hansen, A Adame, L Crews, F Bard, C Lee, P Seubert, ... Neurology 64 (1), 129-131, 2005 | 455 | 2005 |
| Non-Fc-mediated mechanisms are involved in clearance of amyloid-β in vivo by immunotherapy BJ Bacskai, ST Kajdasz, ME McLellan, D Games, P Seubert, D Schenk, ... Journal of Neuroscience 22 (18), 7873-7878, 2002 | 415 | 2002 |
| Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP transgenic mice L McConlogue, M Buttini, JP Anderson, EF Brigham, KS Chen, ... Journal of Biological Chemistry 282 (36), 26326-26334, 2007 | 377 | 2007 |
| Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models D Games, E Valera, B Spencer, E Rockenstein, M Mante, A Adame, ... Journal of Neuroscience 34 (28), 9441-9454, 2014 | 351 | 2014 |
| Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice J Larson, G Lynch, D Games, P Seubert Brain research 840 (1-2), 23-35, 1999 | 351 | 1999 |
