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Luca Miglietta
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Handheld point-of-care system for rapid detection of SARS-CoV-2 extracted RNA in under 20 min
J Rodriguez-Manzano, K Malpartida-Cardenas, N Moser, I Pennisi, ...
ACS central science 7 (2), 307-317, 2021
122*2021
Amplification curve analysis: data-driven multiplexing using real-time digital PCR
A Moniri, L Miglietta, K Malpartida-Cardenas, I Pennisi, ...
Analytical Chemistry 92 (19), 13134-13143, 2020
382020
High-level multiplexing in digital PCR with intercalating dyes by coupling real-time kinetics and melting curve analysis
A Moniri, L Miglietta, A Holmes, P Georgiou, J Rodriguez-Manzano
Analytical Chemistry 92 (20), 14181-14188, 2020
182020
Coupling machine learning and high throughput multiplex digital PCR enables accurate detection of carbapenem-resistant genes in clinical isolates
L Miglietta, A Moniri, I Pennisi, K Malpartida-Cardenas, H Abbas, ...
Frontiers in molecular biosciences 8, 775299, 2021
162021
Discovery and validation of a three-gene signature to distinguish COVID-19 and other viral infections in emergency infectious disease presentations: a case-control and …
HK Li, M Kaforou, J Rodriguez-Manzano, S Channon-Wells, A Moniri, ...
The Lancet Microbe 2 (11), e594-e603, 2021
152021
Next-generation molecular diagnostics: Leveraging digital technologies to enhance multiplexing in real-time PCR
L Kreitmann, L Miglietta, K Xu, K Malpartida-Cardenas, G D'Souza, ...
TrAC Trends in Analytical Chemistry 160, 116963, 2023
92023
Discrimination of bacterial and viral infection using host-RNA signatures integrated in a lab-on-chip platform
I Pennisi, A Moniri, N Miscourides, L Miglietta, N Moser, ...
Biosensors and Bioelectronics 216, 114633, 2022
92022
Quantitative detection of dengue serotypes using a smartphone-connected handheld Lab-on-Chip platform
N Moser, LS Yu, J Rodriguez Manzano, K Malpartida-Cardenas, A Au, ...
Frontiers in Bioengineering and Biotechnology, 1434, 2022
92022
Single-channel digital LAMP multiplexing using amplification curve analysis
K Malpartida-Cardenas, L Miglietta, T Peng, A Moniri, A Holmes, ...
Sensors & diagnostics 1 (3), 465-468, 2022
82022
Diagnosis of multisystem inflammatory syndrome in children by a whole-blood transcriptional signature
HR Jackson, L Miglietta, D Habgood-Coote, G D’Souza, P Shah, ...
Journal of the Pediatric Infectious Diseases Society 12 (6), 322-331, 2023
72023
Adaptive filtering framework to remove nonspecific and low-efficiency reactions in multiplex digital PCR based on sigmoidal trends
L Miglietta, K Xu, P Chhaya, L Kreitmann, K Hill-Cawthorne, F Bolt, ...
Analytical Chemistry 94 (41), 14159-14168, 2022
62022
Discovery and validation of a 3-gene transcriptional signature to distinguish COVID-19 and other viral infections from bacterial sepsis in adults; a case-control then …
HK Li, M Kaforou, J Rodriguez-Manzano, S Channon-Wells, A Moniri, ...
52021
Deep domain adaptation enhances amplification curve analysis for single-channel multiplexing in real-time PCR
Y Mao, K Xu, L Miglietta, L Kreitmann, N Moser, P Georgiou, A Holmes, ...
IEEE journal of biomedical and health informatics, 2023
32023
Smart-Plexer: a breakthrough workflow for hybrid development of multiplex PCR assays
L Miglietta, Y Chen, Z Luo, K Xu, N Ding, T Peng, A Moniri, L Kreitmann, ...
Communications Biology 6 (1), 922, 2023
22023
Integrated patient network and genomic plasmid analysis reveal a regional, multi-species outbreak of carbapenemase-producing Enterobacterales 2 carrying both blaIMP and mcr-9 …
A Boonyasiri, AC Myall, Y Wan, F Bolt, A Ledda, S Mookerjee, AY Weiße, ...
pathways 41, 42, 2021
22021
Identifying a target nucleic acid
JR MANZANO, A Moniri, L Miglietta, P Georgiou
US Patent App. 18/042,285, 2023
2023
DIAGNOSIS OF MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN BY A WHOLE-BLOOD TRANSCRIPTIONAL SIGNATURE
Levin M, Kaforou M, Rodriguez-Manzano J, Jackson H, Miglietta L, Burns J
GB Patent App. 2308744.8, 2023
2023
A Rapid, Portable, and Electricity-Free Sample Extraction Method for Enhanced Molecular Diagnostics in Resource-Limited Settings
I Pennisi, ML Cavuto, L Miglietta, K Malpartida Cardenas, O Stringer, ...
medRxiv, 2023.11. 06.23298007, 2023
2023
Differentiation of COVID-19 from other emergency infectious disease presentations using whole blood transcriptomics then rapid qPCR: a case-control and observational cohort study
HK Li, HR Jackson, L Miglietta, D Habgood-Coote, E Mills, R Mehta, ...
medRxiv, 2023.09. 03.23294989, 2023
2023
The art of PCR assay development: data-driven multiplexing
L Miglietta
Imperial College London, 2023
2023
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