Optimized base editors enable efficient editing in cells, organoids and mice MP Zafra, EM Schatoff, A Katti, M Foronda, M Breinig, AY Schweitzer, ... Nature biotechnology 36 (9), 888-893, 2018 | 312 | 2018 |
Adenine base editing in an adult mouse model of tyrosinaemia CQ Song, T Jiang, M Richter, LH Rhym, LW Koblan, MP Zafra, ... Nature biomedical engineering 4 (1), 125-130, 2020 | 155 | 2020 |
Exosome secretion by eosinophils: A possible role in asthma pathogenesis C Mazzeo, JA Cañas, MP Zafra, AR Marco, M Fernández-Nieto, V Sanz, ... Journal of Allergy and Clinical Immunology 135 (6), 1603-1613, 2015 | 123 | 2015 |
R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine T Han, EM Schatoff, C Murphy, MP Zafra, JE Wilkinson, O Elemento, ... Nature communications 8 (1), 15945, 2017 | 110 | 2017 |
New shrimp IgE‐binding proteins involved in mite‐seafood cross‐reactivity C Gámez, MP Zafra, M Boquete, V Sanz, C Mazzeo, MD Ibáñez, ... Molecular nutrition & food research 58 (9), 1915-1925, 2014 | 95 | 2014 |
An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants MP Zafra, MJ Parsons, J Kim, D Alonso-Curbelo, S Goswami, EM Schatoff, ... Cancer discovery 10 (11), 1654-1671, 2020 | 87 | 2020 |
Distinct colorectal cancer–associated apc mutations dictate response to tankyrase inhibition EM Schatoff, S Goswami, MP Zafra, M Foronda, M Shusterman, BI Leach, ... Cancer discovery 9 (10), 1358-1371, 2019 | 64 | 2019 |
Lineage reversion drives WNT independence in intestinal cancer T Han, S Goswami, Y Hu, F Tang, MP Zafra, C Murphy, Z Cao, JT Poirier, ... Cancer discovery 10 (10), 1590-1609, 2020 | 57 | 2020 |
Simulated gastrointestinal digestion reduces the allergic reactivity of shrimp extract proteins and tropomyosin C Gámez, MP Zafra, V Sanz, C Mazzeo, MD Ibáñez, J Sastre, V del Pozo Food Chemistry 173, 475-481, 2015 | 57 | 2015 |
Gene silencing of SOCS3 by siRNA intranasal delivery inhibits asthma phenotype in mice Ma Paz Zafra, C Mazzeo, C Gámez, A Rodriguez Marco, A de Zulueta, ... PloS one 9 (3), e91996, 2014 | 54 | 2014 |
In situ CRISPR‐Cas9 base editing for the development of genetically engineered mouse models of breast cancer S Annunziato, C Lutz, L Henneman, J Bhin, K Wong, B Siteur, ... The EMBO journal 39 (5), e102169, 2020 | 48 | 2020 |
Gene expression profiling in lungs of chronic asthmatic mice treated with galectin-3: downregulation of inflammatory and regulatory genes E Lopez, MP Zafra, B Sastre, C Gámez, C Lahoz, V del Pozo Mediators of inflammation 2011, 2011 | 33 | 2011 |
GO: a functional reporter system to identify and enrich base editing activity A Katti, M Foronda, J Zimmerman, B Diaz, MP Zafra, S Goswami, LE Dow Nucleic acids research 48 (6), 2841-2852, 2020 | 29 | 2020 |
Suppressors of Cytokine Signaling 3 Expression in Eosinophils: Regulation by PGE2 and Th2 Cytokines E López, MP Zafra, B Sastre, C Gámez, M Fernández-Nieto, J Sastre, ... Journal of Immunology Research 2011, 2011 | 24 | 2011 |
SOCS3 silencing attenuates eosinophil functions in asthma patients MP Zafra, JA Cañas, C Mazzeo, C Gámez, V Sanz, M Fernández-Nieto, ... International Journal of Molecular Sciences 16 (3), 5434-5451, 2015 | 22 | 2015 |
Base editing the mammalian genome EM Schatoff, MP Zafra, LE Dow Methods 164, 100-108, 2019 | 19 | 2019 |
Misregulation of suppressors of cytokine signaling in eosinophilic esophagitis MP Zafra, N Cancelliere, P Rodríguez del Río, M Ruiz-García, L Estévez, ... Journal of gastroenterology 48, 910-920, 2013 | 18 | 2013 |
Biased binding of class IA phosphatidyl inositol 3-kinase subunits to inducible costimulator (CD278) YY Acosta, MP Zafra, G Ojeda, IS Bernardone, U Dianzani, P Portolés, ... Cellular and Molecular Life Sciences 68, 3065-3079, 2011 | 18 | 2011 |
Acute generalized exanthematic pustulosis due to ibuprofen L Arochena, MP Zafra, MC Fariña, V Del Pozo, M Fernández-Nieto Annals of Allergy, Asthma & Immunology 110 (5), 386-387, 2013 | 16 | 2013 |
Detection of marker-free precision genome editing and genetic variation through the capture of genomic signatures P Billon, TS Nambiar, SB Hayward, MP Zafra, EM Schatoff, K Oshima, ... Cell reports 30 (10), 3280-3295. e6, 2020 | 7 | 2020 |