| Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase DC Scott, JT Hammill, J Min, DY Rhee, M Connelly, VO Sviderskiy, ... Nature chemical biology 13 (8), 850-857, 2017 | 92 | 2017 |
| A myristoylated cell-penetrating peptide bearing a transferrin receptor-targeting sequence for neuro-targeted siRNA delivery P Youn, Y Chen, DY Furgeson Molecular Pharmaceutics 11 (2), 486-495, 2014 | 85 | 2014 |
| Discovery of an orally bioavailable inhibitor of defective in cullin neddylation 1 (DCN1)-mediated cullin neddylation JT Hammill, D Bhasin, DC Scott, J Min, Y Chen, Y Lu, L Yang, HS Kim, ... Journal of medicinal chemistry 61 (7), 2694-2706, 2018 | 52 | 2018 |
| Incorporating natural products, pharmaceutical drugs, self-care and digital/mobile health technologies into molecular-behavioral combination therapies for chronic diseases G Bulaj, M M Ahern, A Kuhn, Z S Judkins, R C Bowen, Y Chen Current clinical pharmacology 11 (2), 128-145, 2016 | 39 | 2016 |
| Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening D Ortiz, WA Guiguemde, JT Hammill, AK Carrillo, Y Chen, M Connelly, ... PLoS neglected tropical diseases 11 (12), e0006157, 2017 | 36 | 2017 |
| Optimization of a novel series of ataxia-telangiectasia mutated kinase inhibitors as potential radiosensitizing agents J Min, K Guo, PK Suryadevara, F Zhu, G Holbrook, Y Chen, C Feau, ... Journal of medicinal chemistry 59 (2), 559-577, 2016 | 36 | 2016 |
| Discovery of novel pyrazolo-pyridone DCN1 inhibitors controlling cullin neddylation HS Kim, JT Hammill, DC Scott, Y Chen, J Min, J Rector, B Singh, ... Journal of medicinal chemistry 62 (18), 8429-8442, 2019 | 32 | 2019 |
| Lisocabtagene maraleucel in chronic lymphocytic leukaemia and small lymphocytic lymphoma (TRANSCEND CLL 004): a multicentre, open-label, single-arm, phase 1–2 study T Siddiqi, DG Maloney, SS Kenderian, DM Brander, K Dorritie, ... The Lancet 402 (10402), 641-654, 2023 | 28 | 2023 |
| Thermo-targeted drug delivery of geldanamycin to hyperthermic tumor margins with diblock elastin-based biopolymers Y Chen, P Youn, DY Furgeson Journal of controlled release 155 (2), 175-183, 2011 | 26 | 2011 |
| Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins SK Ippagunta, JA Pollock, N Sharma, W Lin, T Chen, K Tawaratsumida, ... Science signaling 11 (543), eaaq1077, 2018 | 20 | 2018 |
| Expressions and purification of a mature form of recombinant human Chemerin in Escherichia coli D Xiang, J Zhang, Y Chen, Y Guo, A Schalow, Z Zhang, X Hu, H Yu, ... Protein expression and purification 69 (2), 153-158, 2010 | 18 | 2010 |
| Cytoprotection against beta-amyloid (Aβ) peptide-mediated oxidative damage and autophagy by Keap1 RNAi in human glioma U87mg cells P Youn, Y Chen, DY Furgeson Neuroscience research 94, 70-78, 2015 | 12 | 2015 |
| Discovery of a diaminopyrimidine FLT3 inhibitor active against acute myeloid leukemia JA Jarusiewicz, JY Jeon, MC Connelly, Y Chen, L Yang, SD Baker, ... ACS omega 2 (5), 1985-2009, 2017 | 11 | 2017 |
| Improvement of oral bioavailability of pyrazolo-pyridone inhibitors of the interaction of DCN1/2 and UBE2M HS Kim, JT Hammill, DC Scott, Y Chen, AL Rice, W Pistel, B Singh, ... Journal of medicinal chemistry 64 (9), 5850-5862, 2021 | 10 | 2021 |
| Tumour eradication using synchronous thermal ablation and Hsp90 chemotherapy with protein engineered triblock biopolymer-geldanamycin conjugates Y Chen, P Youn, TJ Pysher, CL Scaife, DY Furgeson International Journal of Hyperthermia 30 (8), 550-564, 2014 | 9 | 2014 |
| Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones Y Chen, F Zhu, J Hammill, G Holbrook, L Yang, B Freeman, KL White, ... Malaria Journal 20, 1-15, 2021 | 8 | 2021 |
| Amino-substituted 3-Aryl-and 3-heteroarylquinolines as potential antileishmanial agents JT Hammill, VM Sviripa, LM Kril, D Ortiz, CM Fargo, HS Kim, Y Chen, ... Journal of Medicinal Chemistry 64 (16), 12152-12162, 2021 | 6 | 2021 |
| Effect of fluconazole on the pharmacokinetics of a single dose of fedratinib in healthy adults Y Chen, K Ogasawara, R Wood-Horrall, M Thomas, M Thomas, B He, ... Cancer chemotherapy and pharmacology 90 (4), 325-334, 2022 | 3 | 2022 |
| Optimization of Orally Bioavailable Antileishmanial 2, 4, 5-Trisubstituted Benzamides HS Kim, D Ortiz, TM Kadayat, CM Fargo, JT Hammill, Y Chen, AL Rice, ... Journal of Medicinal Chemistry 66 (11), 7374-7386, 2023 | 2 | 2023 |
| Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase VO Connelly, D Bhasin, Y Chen, SS Ong, SC Chai, AN Goktug, G Huang, ... Interaction 3, 4, 0 | | |
