Bias factor and therapeutic window correlate to predict safer opioid analgesics CL Schmid, NM Kennedy, NC Ross, KM Lovell, Z Yue, J Morgenweck, ... Cell 171 (5), 1165-1175. e13, 2017 | 480 | 2017 |
Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis JR Doherty, C Yang, KEN Scott, MD Cameron, M Fallahi, W Li, MA Hall, ... Cancer research 74 (3), 908-920, 2014 | 393 | 2014 |
Amygdala-Dependent Fear Is Regulated by Oprl1 in Mice and Humans with PTSD R Andero, SP Brothers, T Jovanovic, YT Chen, H Salah-Uddin, ... Science translational medicine 5 (188), 188ra73-188ra73, 2013 | 162 | 2013 |
Total Synthesis of (−)-Bafilomycin A1 KA Scheidt, TD Bannister, A Tasaka, MD Wendt, BM Savall, GJ Fegley, ... Journal of the American Chemical Society 124 (24), 6981-6990, 2002 | 151 | 2002 |
Benzimidazole-and benzoxazole-based inhibitors of Rho kinase EH Sessions, Y Yin, TD Bannister, A Weiser, E Griffin, J Pocas, ... Bioorganic & medicinal chemistry letters 18 (24), 6390-6393, 2008 | 107 | 2008 |
Method of treating addiction or dependence using a ligand for a monamine receptor or transporter BM Aquila, TD Bannister, GD Cuny, JR Hauske, JM Holland, PE Persons, ... US Patent 7,294,637, 2007 | 103 | 2007 |
Compounds and methods for treatment of thrombosis SS Abdel-Meguid, RE Babine, H Deng, L Jin, J Lin, SR Magee, ... US Patent 7,217,794, 2007 | 89 | 2007 |
Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants J Lin, H Deng, L Jin, P Pandey, J Quinn, S Cantin, MJ Rynkiewicz, ... Journal of medicinal chemistry 49 (26), 7781-7791, 2006 | 84 | 2006 |
Total Synthesis of (−)‐Bafilomycin A1: Application of Diastereoselective Crotylboration and Methyl Ketone Aldol Reactions KA Scheidt, A Tasaka, TD Bannister, MD Wendt, WR Roush Angewandte Chemie International Edition 38 (11), 1652-1655, 1999 | 81 | 1999 |
Studies on the Synthesis of Bafilomycin A1: Stereochemical Aspects of the Fragment Assembly Aldol Reaction for Construction of the C(13)−C(25) Segment WR Roush, TD Bannister, MD Wendt, JA Jablonowski, KA Scheidt The Journal of Organic Chemistry 67 (12), 4275-4283, 2002 | 80 | 2002 |
KLF5 is induced by FOXO1 and causes oxidative stress and diabetic cardiomyopathy ID Kyriazis, M Hoffman, L Gaignebet, AM Lucchese, E Markopoulou, ... Circulation research 128 (3), 335-357, 2021 | 76 | 2021 |
Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an α-ketothiazole arginine H Deng, TD Bannister, L Jin, RE Babine, J Quinn, P Nagafuji, CA Celatka, ... Bioorganic & medicinal chemistry letters 16 (11), 3049-3054, 2006 | 71 | 2006 |
Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker DJ Richard, R Lena, T Bannister, N Blake, WE Pierceall, NE Carlson, ... Bioorganic & medicinal chemistry 21 (21), 6642-6649, 2013 | 68 | 2013 |
AG protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal TW Grim, CL Schmid, EL Stahl, F Pantouli, JH Ho, A Acevedo-Canabal, ... Neuropsychopharmacology 45 (2), 416-425, 2020 | 66 | 2020 |
Site‐Selective γ‐C(sp3)−H and γ‐C(sp2)−H Arylation of Free Amino Esters Promoted by a Catalytic Transient Directing Group H Lin, C Wang, TD Bannister, TM Kamenecka Chemistry–A European Journal 24 (38), 9535-9541, 2018 | 65 | 2018 |
Synthesis and structure–activity relationships of pteridine dione and trione monocarboxylate transporter 1 inhibitors H Wang, C Yang, JR Doherty, WR Roush, JL Cleveland, TD Bannister Journal of medicinal chemistry 57 (17), 7317-7324, 2014 | 60 | 2014 |
Optimization of a series of mu opioid receptor (MOR) agonists with high G protein signaling bias NM Kennedy, CL Schmid, NC Ross, KM Lovell, Z Yue, YT Chen, ... Journal of medicinal chemistry 61 (19), 8895-8907, 2018 | 57 | 2018 |
Native Directed Site-Selective δ-C(sp3)–H and δ-C(sp2)–H Arylation of Primary Amines H Lin, X Pan, AL Barsamian, TM Kamenecka, TD Bannister ACS Catalysis 9 (6), 4887-4891, 2019 | 56 | 2019 |
Chroman-3-amides as potent Rho kinase inhibitors YT Chen, TD Bannister, A Weiser, E Griffin, L Lin, C Ruiz, MD Cameron, ... Bioorganic & medicinal chemistry letters 18 (24), 6406-6409, 2008 | 56 | 2008 |
Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening AB Bialkowska, M Crisp, T Bannister, Y He, S Chowdhury, S Schürer, ... Molecular cancer therapeutics 10 (11), 2043-2051, 2011 | 55 | 2011 |