Role of the C-terminal tyrosine of ferredoxin-nicotinamide adenine dinucleotide phosphate reductase in the electron transfer processes with its protein partners ferredoxin and … I Nogués, J Tejero, JK Hurley, D Paladini, S Frago, G Tollin, SG Mayhew, ... Biochemistry 43 (20), 6127-6137, 2004 | 73 | 2004 |
Structural analysis of FAD synthetase from Corynebacterium ammoniagenes S Frago, M Martínez-Júlvez, A Serrano, M Medina BMC microbiology 8, 1-16, 2008 | 63 | 2008 |
An exon splice enhancer primes IGF2: IGF2R binding site structure and function evolution C Williams, HJ Hoppe, D Rezgui, M Strickland, BE Forbes, F Grutzner, ... Science 338 (6111), 1209-1213, 2012 | 56 | 2012 |
The Ferredoxin-NADP(H) Reductase from Rhodobacter capsulatus: Molecular Structure and Catalytic Mechanism, I Nogués, I Pérez-Dorado, S Frago, C Bittel, SG Mayhew, ... Biochemistry 44 (35), 11730-11740, 2005 | 47 | 2005 |
Oligomeric state in the crystal structure of modular FAD synthetase provides insights into its sequential catalysis in prokaryotes B Herguedas, M Martínez-Júlvez, S Frago, M Medina, JA Hermoso Journal of molecular biology 400 (2), 218-230, 2010 | 45 | 2010 |
Circulating levels of insulin-like growth factor-II/mannose-6-phosphate receptor in obesity and type 2 diabetes N Jeyaratnaganthan, K Højlund, JP Kroustrup, JF Larsen, M Bjerre, ... Growth Hormone & IGF Research 20 (3), 185-191, 2010 | 38 | 2010 |
The puzzle of ligand binding to Corynebacterium ammoniagenes FAD synthetase S Frago, A Velázquez-Campoy, M Medina Journal of biological chemistry 284 (11), 6610-6619, 2009 | 36 | 2009 |
Flavodoxin-Mediated Electron Transfer from Photosystem I to Ferredoxin-NADP+ Reductase in Anabaena: Role of Flavodoxin Hydrophobic Residues in Protein … G Goñi, A Serrano, S Frago, M Hervás, JR Peregrina, MA De la Rosa, ... Biochemistry 47 (4), 1207-1217, 2008 | 36 | 2008 |
Functional evolution of IGF2: IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist S Frago, RD Nicholls, M Strickland, J Hughes, C Williams, L Garner, ... Proceedings of the National Academy of Sciences 113 (20), E2766-E2775, 2016 | 35 | 2016 |
Role of key residues at the flavin mononucleotide (FMN): adenylyltransferase catalytic site of the bifunctional riboflavin kinase/flavin adenine dinucleotide (FAD) Synthetase … A Serrano, S Frago, A Velázquez-Campoy, M Medina International journal of molecular sciences 13 (11), 14492-14517, 2012 | 35 | 2012 |
Tuning of the FMN binding and oxido-reduction properties by neighboring side chains in Anabaena flavodoxin S Frago, G Goni, B Herguedas, JR Peregrina, A Serrano, I Perez-Dorado, ... Archives of biochemistry and biophysics 467 (2), 206-217, 2007 | 28 | 2007 |
Key Residues at the Riboflavin Kinase Catalytic Site of the Bifunctional Riboflavin Kinase/FMN Adenylyltransferase From Corynebacterium ammoniagenes A Serrano, S Frago, B Herguedas, M Martínez-Júlvez, ... Cell biochemistry and biophysics 65, 57-68, 2013 | 26 | 2013 |
Dual role of FMN in flavodoxin function: Electron transfer cofactor and modulation of the protein–protein interaction surface S Frago, I Lans, JA Navarro, M Hervás, DE Edmondson, A Miguel, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1797 (2), 262-271, 2010 | 23 | 2010 |
Crystallization and preliminary X-ray diffraction studies of FAD synthetase from Corynebacterium ammoniagenes B Herguedas, M Martinez-Julvez, S Frago, M Medina, JA Hermoso Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009 | 15 | 2009 |
Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2rI1565A) results in partial lethality, overgrowth and intestinal adenoma progression J Hughes, M Surakhy, S Can, M Ducker, N Davies, F Szele, ... Scientific Reports 9 (1), 11388, 2019 | 13 | 2019 |
Towards a new interaction enzyme: coenzyme M Martínez-Júlvez, J Tejero, JR Peregrina, I Nogués, S Frago, ... Biophysical chemistry 115 (2-3), 219-224, 2005 | 13 | 2005 |
Probing the role of glutamic acid 139 of Anabaena ferredoxin‐NADP+ reductase in the interaction with substrates M Faro, S Frago, T Mayoral, JA Hermoso, J Sanz‐Aparicio, ... European journal of biochemistry 269 (20), 4938-4947, 2002 | 11 | 2002 |
Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype J Hughes, S Frago, C Bühnemann, EJ Carter, AB Hassan PLoS One 8 (2), e57270, 2013 | 10 | 2013 |
Understanding the FMN cofactor chemistry within the Anabaena Flavodoxin environment I Lans, S Frago, M Medina Biochimica et Biophysica Acta (BBA)-Bioenergetics 1817 (12), 2118-2127, 2012 | 10 | 2012 |
Characterization of the recombinant copper chaperone (CCS) from the plant Glycine (G.) max. S Sagasti, I Yruela, M Bernal, MA Lujan, S Frago, M Medina, R Picorel Metallomics 3 (2), 169-175, 2011 | 7 | 2011 |