| Anti‐cell death engineering of CHO cells: Co‐overexpression of Bcl‐2 for apoptosis inhibition, Beclin‐1 for autophagy induction JS Lee, TK Ha, JH Park, GM Lee Biotechnology and bioengineering 110 (8), 2195-2207, 2013 | 73 | 2013 |
| Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion TB Kallehauge, S Li, LE Pedersen, TK Ha, D Ley, MR Andersen, ... Scientific reports 7 (1), 40388, 2017 | 61 | 2017 |
| Effect of glutamine substitution by TCA cycle intermediates on the production and sialylation of Fc-fusion protein in Chinese hamster ovary cell culture TK Ha, GM Lee Journal of biotechnology 180, 23-29, 2014 | 55 | 2014 |
| Revealing key determinants of clonal variation in transgene expression in recombinant CHO cells using targeted genome editing JS Lee, JH Park, TK Ha, M Samoudi, NE Lewis, BO Palsson, ... ACS Synthetic Biology 7 (12), 2867-2878, 2018 | 49 | 2018 |
| Autophagy and apoptosis of recombinant Chinese hamster ovary cells during fed‐batch culture: Effect of nutrient supplementation YK Han, TK Ha, SJ Lee, JS Lee, GM Lee Biotechnology and bioengineering 108 (9), 2182-2192, 2011 | 49 | 2011 |
| Current state and perspectives on erythropoietin production JS Lee, TK Ha, SJ Lee, GM Lee Applied Microbiology and Biotechnology 95, 1405-1416, 2012 | 43 | 2012 |
| Effect of lithium chloride on the production and sialylation of Fc-fusion protein in Chinese hamster ovary cell culture TK Ha, YG Kim, GM Lee Applied microbiology and biotechnology 98, 9239-9248, 2014 | 36 | 2014 |
| Baicalein reduces oxidative stress in CHO cell cultures and improves recombinant antibody productivity TK Ha, AH Hansen, S Kol, HF Kildegaard, GM Lee Biotechnology Journal 13 (3), 1700425, 2018 | 35 | 2018 |
| Understanding of altered N‐glycosylation‐related gene expression in recombinant Chinese hamster ovary cells subjected to elevated ammonium concentration by … TK Ha, YG Kim, GM Lee Biotechnology and Bioengineering 112 (8), 1583-1593, 2015 | 35 | 2015 |
| Reprogramming AA catabolism in CHO cells with CRISPR/Cas9 genome editing improves cell growth and reduces byproduct secretion D Ley, S Pereira, LE Pedersen, J Arnsdorf, H Hefzi, AM Davy, TK Ha, ... Metabolic engineering 56, 120-129, 2019 | 31 | 2019 |
| Factors affecting the quality of therapeutic proteins in recombinant Chinese hamster ovary cell culture TK Ha, D Kim, CL Kim, LM Grav, GM Lee Biotechnology Advances 54, 107831, 2022 | 28 | 2022 |
| Knockout of sialidase and pro-apoptotic genes in Chinese hamster ovary cells enables the production of recombinant human erythropoietin in fed-batch cultures TK Ha, AH Hansen, HF Kildegaard, GM Lee Metabolic engineering 57, 182-192, 2020 | 21 | 2020 |
| Bcl-xL overexpression delays the onset of autophagy and apoptosis in hyperosmotic recombinant Chinese hamster ovary cell cultures YK Han, TK Ha, YG Kim, GM Lee Journal of biotechnology 156 (1), 52-55, 2011 | 20 | 2011 |
| BiP inducer X: an ER stress inhibitor for enhancing recombinant antibody production in CHO cell culture TK Ha, AH Hansen, HF Kildegaard, GM Lee Biotechnology Journal 14 (10), 1900130, 2019 | 19 | 2019 |
| Proteomic understanding of intracellular responses of recombinant chinese hamster ovary cells adapted to grow in serum‐free suspension culture JY Baik, TK Ha, YH Kim, GM Lee Biotechnology progress 27 (6), 1680-1688, 2011 | 19 | 2011 |
| Glutamine substitution: the role it can play to enhance therapeutic protein production TK Ha, GM Lee Pharm Bioprocess 3 (3), 249-261, 2015 | 14 | 2015 |
| Combinatorial treatment with lithium chloride enhances recombinant antibody production in transiently transfected CHO and HEK293E cells CL Kim, TK Ha, GM Lee Biotechnology and Bioprocess Engineering 21, 667-675, 2016 | 7 | 2016 |
| Effect of Bcl‐xL overexpression on lactate metabolism in chinese hamster ovary cells producing antibody TK Ha, MK Jeon, D Yu, GM Lee Biotechnology Progress 29 (6), 1594-1598, 2013 | 7 | 2013 |
| Platform Technology for Therapeutic Protein Production TK Ha, JS Lee, GM Lee Cell Culture Engineering: Recombinant Protein Production, 1-22, 2019 | 6 | 2019 |
| Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium TK Ha, A Òdena, KJC Karottki, CL Kim, H Hefzi, GM Lee, ... Biotechnology and Bioengineering 120 (4), 1159-1166, 2023 | 4 | 2023 |
