Engineering enzymes for noncanonical amino acid synthesis PJ Almhjell, CE Boville, FH Arnold Chemical Society Reviews 47 (24), 8980-8997, 2018 | 106 | 2018 |
Scalable continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities G Rix, EJ Watkins-Dulaney, PJ Almhjell, CE Boville, FH Arnold, CC Liu Nature Communications 11 (1), 5644, 2020 | 77 | 2020 |
In vivo hypermutation and continuous evolution RS Molina, G Rix, AA Mengiste, B Álvarez, D Seo, H Chen, JE Hurtado, ... Nature Reviews Methods Primers 2 (1), 36, 2022 | 59 | 2022 |
Improved Synthesis of 4-Cyanotryptophan and Other Tryptophan Analogues in Aqueous Solvent Using Variants of TrpB from Thermotoga maritima CE Boville, DK Romney, PJ Almhjell, M Sieben, FH Arnold The Journal of organic chemistry 83 (14), 7447-7452, 2018 | 56 | 2018 |
Computational design of a homotrimeric metalloprotein with a trisbipyridyl core JH Mills, W Sheffler, ME Ener, PJ Almhjell, G Oberdorfer, JH Pereira, ... Proceedings of the National Academy of Sciences 113 (52), 15012-15017, 2016 | 43 | 2016 |
evSeq: Cost-Effective Amplicon Sequencing of Every Variant in a Protein Library BJ Wittmann, KE Johnston, PJ Almhjell, FH Arnold ACS Synthetic Biology 11 (3), 1313–1324, 2022 | 28 | 2022 |
Direct enzymatic synthesis of a deep‐blue fluorescent noncanonical amino acid from azulene and serine EJ Watkins, PJ Almhjell, FH Arnold ChemBioChem 21 (1-2), 80-83, 2020 | 26 | 2020 |
Metal-chelating non-canonical amino acids in metalloprotein engineering and design PJ Almhjell, JH Mills Current Opinion in Structural Biology 51, 170-176, 2018 | 20 | 2018 |
Method for the synthesis of tryptophan analogs in aqueous solvents at reduced temperatures CE Boville, DK Romney, PJ Almhjell, MM Sieben US Patent 10,752,927, 2020 | 1 | 2020 |
Engineered Enzymes and Method for the Synthesis of Diverse Tyrosine Analogs PJ Almhjell, FH Arnold US Patent App. 17/985,033, 2023 | | 2023 |
Noncanonical Amino Acid Synthesis by Evolved Tryptophan Synthases PJ Almhjell California Institute of Technology, 2023 | | 2023 |
Computational Design of a Self-Assembling Metalloprotein PJ Almhjell | | 2017 |