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Jeffrey A Johnson
Jeffrey A Johnson
Verified email at wisc.edu
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Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
JM Lee, MJ Calkins, K Chan, YW Kan, JA Johnson
Journal of Biological Chemistry 278 (14), 12029-12038, 2003
9232003
An important role of Nrf2-ARE pathway in the cellular defense mechanism
JM Lee, JA Johnson
BMB Reports 37 (2), 139-143, 2004
9172004
Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
AY Shih, DA Johnson, G Wong, AD Kraft, L Jiang, H Erb, JA Johnson, ...
Journal of Neuroscience 23 (8), 3394-3406, 2003
8752003
The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration
JA Johnson, DA Johnson, AD Kraft, MJ Calkins, RJ Jakel, MR Vargas, ...
Annals of the new York Academy of Sciences 1147, 61, 2008
6742008
Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes …
AD Kraft, DA Johnson, JA Johnson
Journal of Neuroscience 24 (5), 1101-1112, 2004
6432004
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: critical role for the astrocyte
PC Chen, MR Vargas, AK Pani, RJ Smeyne, DA Johnson, YW Kan, ...
Proceedings of the National Academy of Sciences 106 (8), 2933-2938, 2009
6372009
Nrf2, a multi-organ protector?
JM Lee, J Li, DA Johnson, TD Stein, AD Kraft, MJ Calkins, RJ Jakel, ...
The FASEB Journal 19 (9), 1061-1066, 2005
6022005
Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis
MR Vargas, DA Johnson, DW Sirkis, A Messing, JA Johnson
Journal of Neuroscience 28 (50), 13574-13581, 2008
5192008
Inhibition of 7, 12-dimethylbenz (a) anthracene-and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin
AK Verma, JA Johnson, MN Gould, MA Tanner
Cancer research 48 (20), 5754-5758, 1988
4991988
The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease
MJ Calkins, DA Johnson, JA Townsend, MR Vargas, JA Dowell, ...
Antioxidants & redox signaling 11 (3), 497-508, 2009
4782009
Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of …
TD Stein, NJ Anders, C DeCarli, SL Chan, MP Mattson, JA Johnson
Journal of Neuroscience 24 (35), 7707-7717, 2004
4002004
NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons
JM Lee, AY Shih, TH Murphy, JA Johnson
Journal of Biological Chemistry 278 (39), 37948-37956, 2003
3732003
Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell …
TD Stein, JA Johnson
Journal of Neuroscience 22 (17), 7380-7388, 2002
3552002
Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes
MS Yates, M Tauchi, F Katsuoka, KC Flanders, KT Liby, T Honda, ...
Molecular cancer therapeutics 6 (1), 154-162, 2007
3212007
Nrf2—a therapeutic target for the treatment of neurodegenerative diseases
DA Johnson, JA Johnson
Free Radical Biology and Medicine 88, 253-267, 2015
3162015
The Nrf2–ARE cytoprotective pathway in astrocytes
MR Vargas, JA Johnson
Expert reviews in molecular medicine 11, 2009
3022009
Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription
MJ Calkins, RJ Jakel, DA Johnson, K Chan, YW Kan, JA Johnson
Proceedings of the National Academy of Sciences 102 (1), 244-249, 2005
3012005
Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases
L Gan, JA Johnson
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (8 …, 2014
2962014
Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells
JM Lee, JM Hanson, WA Chu, JA Johnson
Journal of biological chemistry 276 (23), 20011-20016, 2001
2912001
Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells
J Li, D Johnson, M Calkins, L Wright, C Svendsen, J Johnson
Toxicological Sciences 83 (2), 313-328, 2005
2792005
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