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| Potent and selective covalent quinazoline inhibitors of KRAS G12C M Zeng, J Lu, L Li, F Feru, C Quan, TW Gero, SB Ficarro, Y Xiong, ... Cell chemical biology 24 (8), 1005-1016. e3, 2017 | 138 | 2017 |
| MicroRNA-218 functions as a tumor suppressor in lung cancer by targeting IL-6/STAT3 and negatively correlates with poor prognosis Y Yang, L Ding, Q Hu, J Xia, J Sun, X Wang, H Xiong, D Gurbani, L Li, ... Molecular cancer 16, 1-13, 2017 | 127 | 2017 |
| Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype CM Olson, Y Liang, A Leggett, WD Park, L Li, CE Mills, SZ Elsarrag, ... Cell Chemical Biology 26, 2019 | 119 | 2019 |
| Discovery of a selective inhibitor of doublecortin like kinase 1 FM Ferguson, B Nabet, S Raghavan, Y Liu, AL Leggett, M Kuljanin, ... Nature chemical biology 16 (6), 635-643, 2020 | 92 | 2020 |
| Structural and biochemical analyses reveal the mechanism of glutathione S-transferase Pi 1 inhibition by the anti-cancer compound piperlongumine W Harshbarger, S Gondi, SB Ficarro, J Hunter, D Udayakumar, D Gurbani, ... Journal of Biological Chemistry 292 (1), 112-120, 2017 | 83 | 2017 |
| Covalent guanosine mimetic inhibitors of G12C KRAS Y Xiong, J Lu, J Hunter, L Li, D Scott, HG Choi, SM Lim, A Manandhar, ... ACS medicinal chemistry letters 8 (1), 61-66, 2017 | 76 | 2017 |
| A structural model of a Ras–Raf signalosome VP Mysore, ZW Zhou, C Ambrogio, L Li, JN Kapp, C Lu, Q Wang, ... Nature structural & molecular biology 28 (10), 847-857, 2021 | 57 | 2021 |
| KRASQ61H Preferentially Signals through MAPK in a RAF Dimer-Dependent Manner in Non–Small Cell Lung CancerKRASQ61H Signals in a RAF Dimer-Dependent Manner ZW Zhou, C Ambrogio, AK Bera, Q Li, XX Li, L Li, J Son, S Gondi, J Li, ... Cancer research 80 (17), 3719-3731, 2020 | 47 | 2020 |
| Structure-guided development of covalent TAK1 inhibitors L Tan, D Gurbani, EL Weisberg, JC Hunter, L Li, DS Jones, SB Ficarro, ... Bioorganic & medicinal chemistry 25 (3), 838-846, 2017 | 33 | 2017 |
| KRAS G12C drug development: discrimination between switch II pocket configurations using hydrogen/deuterium-exchange mass spectrometry J Lu, RA Harrison, L Li, M Zeng, S Gondi, D Scott, NS Gray, JR Engen, ... Structure 25 (9), 1442-1448. e3, 2017 | 32 | 2017 |
| Structural Insights on the bacteriolytic and self-protection mechanism of muramidase effector Tse3 in Pseudomonas aeruginosa L Li, W Zhang, Q Liu, Y Gao, Y Gao, Y Wang, DZ Wang, Z Li, T Wang Journal of Biological Chemistry 288 (42), 30607-30613, 2013 | 30 | 2013 |
| Chemical biology toolkit for DCLK1 reveals connection to RNA processing Y Liu, FM Ferguson, L Li, M Kuljanin, CE Mills, K Subramanian, ... Cell chemical biology 27 (10), 1229-1240. e4, 2020 | 21 | 2020 |
| Rationale for RAS mutation-tailored therapies SK Montalvo, L Li, KD Westover Future Oncology 13 (3), 263-271, 2017 | 17 | 2017 |
| Thermal shift assay for small GTPase stability screening: evaluation and suitability K Kopra, S Valtonen, R Mahran, JN Kapp, N Hassan, W Gillette, B Dennis, ... International journal of molecular sciences 23 (13), 7095, 2022 | 14 | 2022 |
| TCF3 inhibits F9 embryonal carcinoma growth by the down-regulation of Oct4 G Lin, L Zhao, F Yin, R Lan, L Li, X Zhang, H Zhang, B Yang Oncology reports 26 (4), 893-899, 2011 | 12 | 2011 |
| The p38‐interacting protein p38IP suppresses TCR and LPS signaling by targeting TAK1 XD Wang, CS Zhao, QL Wang, Q Zeng, XZ Feng, L Li, ZL Chen, Y Gong, ... EMBO reports 21 (7), e48035, 2020 | 10 | 2020 |
| Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1 W Lu, Y Liu, Y Gao, Q Geng, D Gurbani, L Li, SB Ficarro, CJ Meyer, ... Journal of Medicinal Chemistry 66 (5), 3356-3371, 2023 | 6 | 2023 |
| Genome-wide trait-trait dynamics correlation study dissects the gene regulation pattern in maize kernels X Xu, M Wang, L Li, R Che, P Li, L Pei, H Li BMC plant biology 17, 1-12, 2017 | 6 | 2017 |
| ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS–ERK–AP-1 T cell signaling-transcriptional axis NGP Ramirez, J Lee, Y Zheng, L Li, B Dennis, D Chen, A Challa, ... Nature communications 13 (1), 1109, 2022 | 5 | 2022 |
Ken WestoverAssociate Professor of Biochemistry and Radiation Oncology, UT SouthwesternVerified email at utsouthwestern.edu
