| In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion A Ianus, GG Holz, ND Theise, MA Hussain The Journal of Clinical Investigation 111 (6), 843-850, 2003 | 1088 | 2003 |
| Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1 (7-37) GG Holz IV, WM Kuhtreiber, JF Habener Nature 361 (6410), 362-365, 1993 | 809 | 1993 |
| GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels GG Holz IV, SG Rane, K Dunlap Nature 319 (6055), 670-672, 1986 | 797 | 1986 |
| Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic β-cells TJ Kieffer, RS Heller, CA Leech, GG Holz, JF Habener Diabetes 46 (6), 1087-1093, 1997 | 725 | 1997 |
| Leptin Suppression of Insulin Secretion and Gene Expression in Human Pancreatic Islets: Implications for the Development of Adipogenic Diabetes Mellitus J Seufert, TJ Kieffer, CA Leech, GG Holz, W Moritz, C Ricordi, JF Habener The Journal of Clinical Endocrinology & Metabolism 84 (2), 670-676, 1999 | 527 | 1999 |
| Epac: a new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic β-cell GG Holz Diabetes 53 (1), 5-13, 2004 | 514 | 2004 |
| Epac-selective cAMP analog 8-pCPT-2′-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic β-cells G Kang, JW Joseph, OG Chepurny, M Monaco, MB Wheeler, JL Bos, ... Journal of Biological Chemistry 278 (10), 8279-8285, 2003 | 384 | 2003 |
| Cell physiology of cAMP sensor Epac GG Holz, G Kang, M Harbeck, MW Roe, OG Chepurny The Journal of physiology 577 (1), 5-15, 2006 | 324 | 2006 |
| Regulation of glucose homeostasis by GLP-1 P Nadkarni, OG Chepurny, GG Holz Progress in Molecular Biology and Translational Science 121, 23, 2014 | 295 | 2014 |
| cAMP-dependent mobilization of intracellular Ca2+ stores by activation of ryanodine receptors in pancreatic β-cells: a Ca2+ signaling system stimulated by the insulinotropic … GG Holz, CA Leech, RS Heller, M Castonguay, JF Habener Journal of Biological Chemistry 274 (20), 14147-14156, 1999 | 289 | 1999 |
| Activation of a cAMP-regulated Ca2+ signaling pathway in pancreatic beta cells by the insulinotropic hormone glucagon-like peptide-1 GG Holz, CA Leech, JF Habener Journal of Biological Chemistry 270 (30), 17749-17757, 1995 | 257 | 1995 |
| cAMP‐regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+‐induced Ca2+ release in INS‐1 pancreatic β‐cells G Kang, OG Chepurny, GG Holz The Journal of Physiology 536 (2), 375-385, 2001 | 243 | 2001 |
| Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells T Tsuboi, G da Silva Xavier, GG Holz, LS Jouaville, AP Thomas, GA Rutter Biochemical Journal 369 (2), 287-299, 2003 | 235 | 2003 |
| Interplay of Ca2+ and cAMP Signaling in the Insulin-secreting MIN6 β-Cell Line LR Landa, M Harbeck, K Kaihara, O Chepurny, K Kitiphongspattana, ... Journal of Biological Chemistry 280 (35), 31294-31302, 2005 | 224 | 2005 |
| Dihydropyridine inhibition of neuronal calcium current and substance P release SG Rane, GG Holz IV, K Dunlap Pflügers Archiv 409 (4-5), 361-366, 1987 | 221 | 1987 |
| G proteins as regulators of ion channel function K Dunlap, GG Holz, SG Rane Trends in Neurosciences 10 (6), 241-244, 1987 | 218 | 1987 |
| Characterization of the electrically evoked release of substance P from dorsal root ganglion neurons: methods and dihydropyridine sensitivity GG Holz IV, K Dunlap, RM Kream Journal of Neuroscience 8 (2), 463-471, 1988 | 211 | 1988 |
| Glucagon-like peptide-1 synthetic analogs: new therapeutic agents for use in the treatment of diabetes mellitus GG Holz, OG Chepurny Current Medicinal Chemistry 10 (22), 2471-2483, 2003 | 202 | 2003 |
| Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors GG Holz, OG Chepurny, F Schwede Cellular Signalling 20 (1), 10-20, 2008 | 191 | 2008 |
| cAMP sensor Epac as a determinant of ATP‐sensitive potassium channel activity in human pancreatic β cells and rat INS‐1 cells G Kang, OG Chepurny, B Malester, MJ Rindler, H Rehmann, JL Bos, ... The Journal of Physiology 573 (3), 595-609, 2006 | 173 | 2006 |
Robert P. Doyle PhDJack and Laura H. Milton Professor. Chemistry, Syracuse University / Medicine SUNY UpstateVerified email at syr.edu
