Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue N Treiber, P Maity, K Singh, M Kohn, AF Keist, F Ferchiu, L Sante, S Frese, ... Aging cell 10 (2), 239-254, 2011 | 111 | 2011 |
Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS–FTD-linked UBQLN2 mutations NTT Le, L Chang, I Kovlyagina, P Georgiou, N Safren, KE Braunstein, ... Proceedings of the National Academy of Sciences 113 (47), E7580-E7589, 2016 | 93 | 2016 |
Tdp-43 cryptic exons are highly variable between cell types YH Jeong, JP Ling, SZ Lin, AN Donde, KE Braunstein, E Majounie, ... Molecular neurodegeneration 12, 1-9, 2017 | 76 | 2017 |
The neuritic plaque facilitates pathological conversion of tau in an Alzheimer’s disease mouse model T Li, KE Braunstein, J Zhang, A Lau, L Sibener, C Deeble, PC Wong Nature communications 7 (1), 12082, 2016 | 76 | 2016 |
Splicing repression is a major function of TDP-43 in motor neurons A Donde, M Sun, JP Ling, KE Braunstein, B Pang, X Wen, X Cheng, ... Acta neuropathologica 138, 813-826, 2019 | 72 | 2019 |
Mice with a mutation in the dynein heavy chain 1 gene display sensory neuropathy but lack motor neuron disease L Dupuis, A Fergani, KE Braunstein, J Eschbach, N Holl, F Rene, ... Experimental neurology 215 (1), 146-152, 2009 | 72 | 2009 |
A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons KE Braunstein, J Eschbach, K Ròna-Vörös, R Soylu, E Mikrouli, Y Larmet, ... Human molecular genetics 19 (22), 4385-4398, 2010 | 68 | 2010 |
Intraventricular delivery of siRNA nanoparticles to the central nervous system R Shyam, Y Ren, J Lee, KE Braunstein, HQ Mao, PC Wong Molecular Therapy-Nucleic Acids 4, 2015 | 56 | 2015 |
The dynactin p150 subunit: cell biology studies of sequence changes found in ALS/MND and Parkinsonian syndromes M Stockmann, M Meyer-Ohlendorf, K Achberger, S Putz, M Demestre, ... Journal of neural transmission 120, 785-798, 2013 | 48 | 2013 |
Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis KA Britson, JP Ling, KE Braunstein, JM Montagne, JM Kastenschmidt, ... Science translational medicine 14 (628), eabi9196, 2022 | 37 | 2022 |
Expression of constitutively active FoxO3 in murine forebrain leads to a loss of neural progenitors U Schmidt‐Strassburger, TG Schips, HJ Maier, K Kloiber, F Mannella, ... The FASEB Journal 26 (12), 4990-5001, 2012 | 36 | 2012 |
Neuroprotective function of cellular prion protein in a mouse model of amyotrophic lateral sclerosis P Steinacker, A Hawlik, S Lehnert, O Jahn, S Meier, E Görz, ... The American journal of pathology 176 (3), 1409-1420, 2010 | 35 | 2010 |
Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43 A Donde, M Sun, YH Jeong, X Wen, J Ling, S Lin, K Braunstein, S Nie, ... Autophagy 16 (4), 672-682, 2020 | 33 | 2020 |
Vacuolization correlates with spin–spin relaxation time in motor brainstem nuclei and behavioural tests in the transgenic G93A‐SOD1 mouse model of ALS S Bucher, KE Braunstein, HG Niessen, T Kaulisch, M Neumaier, ... European Journal of Neuroscience 26 (7), 1895-1901, 2007 | 33 | 2007 |
A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS–FTD KE Irwin, P Jasin, KE Braunstein, IR Sinha, MA Garret, KD Bowden, ... Nature medicine, 1-12, 2024 | 29 | 2024 |
Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes DW Kim, KJ Tu, A Wei, AJ Lau, A Gonzalez-Gil, T Cao, K Braunstein, ... Molecular neurodegeneration 17 (1), 83, 2022 | 22 | 2022 |
Untersuchungen von Motorik, Kognition und Verhalten bei Mausmodellen von Motoneuronerkrankungen KE Braunstein Universität Ulm, 2016 | 2 | 2016 |
Amyloid-beta and tau pathologies are both necessary to induce novel stage-specific microglia subtypes during Alzheimer’s disease progression DW Kim, K Tu, A Wei, A Lau, A Gonzalez-Gil, T Cao, K Braunstein, ... bioRxiv, 2021.10. 16.464454, 2021 | 1 | 2021 |
New research may lead to early detection of ALS and frontotemporal dementia KE Irwin, P Jasin, KE Braunstein, IR Sinha, MA Garret, KD Bowden, ... | | 2024 |
A novel fluid biomarker for TDP‐43 loss of function KE Irwin, P Jasin, KE Braunstein, I Sinha, KD Bowden, A Moghekar, ... Alzheimer's & Dementia 19, e082829, 2023 | | 2023 |