Structural features of the ligand-binding domain of the serotonin 5HT3 receptor D Yan, MK Schulte, KE Bloom, MM White Journal of Biological Chemistry 274 (9), 5537-5541, 1999 | 109 | 1999 |
Quisqualic acid analogs: synthesis of. beta.-heterocyclic 2-aminopropanoic acid derivatives and their activity at a novel quisqualate-sensitized site N Subasinghe, M Schulte, RJ Roon, JF Koerner, RL Johnson Journal of medicinal chemistry 35 (24), 4602-4607, 1992 | 107 | 1992 |
Synthesis of acyclic and dehydroaspartic acid analogs of Ac-Asp-Glu-OH and their inhibition of rat brain N-acetylated. alpha.-linked acidic dipeptidase (NAALA dipeptidase) N Subasinghe, M Schulte, MYM Chan, RJ Roon, JF Koerner, RL Johnson Journal of medicinal chemistry 33 (10), 2734-2744, 1990 | 85 | 1990 |
Synthesis of desformylflustrabromine and its evaluation as an α4β2 and α7 nACh receptor modulator JS Kim, A Padnya, M Weltzin, BW Edmonds, MK Schulte, RA Glennon Bioorganic & medicinal chemistry letters 17 (17), 4855-4860, 2007 | 79 | 2007 |
Microcantilever biosensors based on conformational change of proteins HF Ji, H Gao, KR Buchapudi, X Yang, X Xu, MK Schulte Analyst 133 (4), 434-443, 2008 | 65 | 2008 |
Pharmacological characterization of the allosteric modulator desformylflustrabromine and its interaction with α4β2 neuronal nicotinic acetylcholine receptor orthosteric ligands MM Weltzin, MK Schulte Journal of Pharmacology and Experimental Therapeutics 334 (3), 917-926, 2010 | 61 | 2010 |
Rabies virus modifies host behaviour through a snake-toxin like region of its glycoprotein that inhibits neurotransmitter receptors in the CNS K Hueffer, S Khatri, S Rideout, MB Harris, RL Papke, C Stokes, ... Scientific reports 7 (1), 12818, 2017 | 47 | 2017 |
Identification of critical residues in loop E in the 5-HT3ASR binding site P Venkataraman, SP Venkatachalan, PR Joshi, M Muthalagi, MK Schulte BMC biochemistry 3, 1-11, 2002 | 45 | 2002 |
2-Amino-6-chloro-3, 4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character M Dukat, K Alix, J Worsham, S Khatri, MK Schulte Bioorganic & medicinal chemistry letters 23 (21), 5945-5948, 2013 | 44 | 2013 |
Interactions of Granisetron with an Agonist-Free 5-HT3A Receptor Model PR Joshi, A Suryanarayanan, E Hazai, MK Schulte, G Maksay, Z Bikádi Biochemistry 45 (4), 1099-1105, 2006 | 44 | 2006 |
Micromechanical measurement of membrane receptor binding for label-free drug discovery Y Zhang, SP Venkatachalan, H Xu, X Xu, P Joshi, HF Ji, M Schulte Biosensors and Bioelectronics 19 (11), 1473-1478, 2004 | 40 | 2004 |
Attenuation of compulsive-like behavior through positive allosteric modulation of α4β2 nicotinic acetylcholine receptors in non-induced compulsive-like mice S Mitra, M Mucha, SN Khatri, R Glenon, MK Schulte, A Bult-Ito Frontiers in Behavioral Neuroscience 10, 244, 2017 | 36 | 2017 |
A vertical flow chamber for Xenopus oocyte electrophysiology and automated drug screening PR Joshi, A Suryanarayanan, MK Schulte Journal of neuroscience methods 132 (1), 69-79, 2004 | 36 | 2004 |
Desformylflustrabromine modulates α4β2 neuronal nicotinic acetylcholine receptor high-and low-sensitivity isoforms at allosteric clefts containing the β2 subunit MM Weltzin, MK Schulte Journal of Pharmacology and Experimental Therapeutics 354 (2), 184-194, 2015 | 33 | 2015 |
Structure-function relationships for analogues ofl-2-amino-4-phosphonobutanoic acid on the quisqualic acid-sensitive AP4 receptor of the rat hippocampus MK Schulte, ER Whittemore, JF Koerner, RL Johnson Brain research 582 (2), 291-298, 1992 | 30 | 1992 |
Structure-function relationships for kynurenic acid analogues at excitatory pathways in the rat hippocampal slice MB Robinson, MK Schulte, RK Freund, RL Johnson, JF Koerner Brain research 361 (1-2), 19-24, 1985 | 28 | 1985 |
Allosteric modulation of α4β2* nicotinic acetylcholine receptors: Desformylflustrabromine potentiates antiallodynic response of nicotine in a mouse model of neuropathic pain D Bagdas, D Ergun, A Jackson, W Toma, MK Schulte, MI Damaj European Journal of Pain 22 (1), 84-93, 2018 | 27 | 2018 |
Deconstruction of the α4β2 nicotinic acetylcholine receptor positive allosteric modulator desformylflustrabromine N German, JS Kim, A Jain, M Dukat, A Pandya, Y Ma, M Weltzin, ... Journal of medicinal chemistry 54 (20), 7259-7267, 2011 | 27 | 2011 |
Functional group interactions of a 5-HT3R antagonist P Venkataraman, P Joshi, SP Venkatachalan, M Muthalagi, HS Parihar, ... BMC biochemistry 3, 1-13, 2002 | 26 | 2002 |
The Loop C Region of the Murine 5-HT3A Receptor Contributes to the Differential Actions of 5-Hydroxytryptamine and m-Chlorophenylbiguanide A Suryanarayanan, PR Joshi, Z Bikádi, M Mani, TR Kulkarni, C Gaines, ... Biochemistry 44 (25), 9140-9149, 2005 | 24 | 2005 |