| The molecular basis of chloroquine block of the inward rectifier Kir2. 1 channel AA Rodríguez-Menchaca, RA Navarro-Polanco, T Ferrer-Villada, J Rupp, ... Proceedings of the National Academy of Sciences 105 (4), 1364-1368, 2008 | 153 | 2008 |
| PIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4–S5 linker AA Rodriguez-Menchaca, SK Adney, QY Tang, XY Meng, ... Proceedings of the National Academy of Sciences 109 (36), E2399-E2408, 2012 | 100 | 2012 |
| Dual Regulation of Voltage-Sensitive Ion Channels by PIP2 AA Rodríguez-Menchaca, SK Adney, L Zhou, DE Logothetis Frontiers in pharmacology 3, 170, 2012 | 64 | 2012 |
| A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P2 A Rosenhouse-Dantsker, JL Sui, Q Zhao, R Rusinova, ... Nature chemical biology 4 (10), 624-631, 2008 | 63 | 2008 |
| Tamoxifen inhibits inward rectifier K+ 2. x family of inward rectifier channels by interfering with phosphatidylinositol 4, 5-bisphosphate-channel interactions D Ponce-Balbuena, A López-Izquierdo, T Ferrer, ... Journal of Pharmacology and Experimental Therapeutics 331 (2), 563-573, 2009 | 52 | 2009 |
| Hypercholesterolemia induces up-regulation of KACh cardiac currents via a mechanism independent of phosphatidylinositol 4, 5-bisphosphate and Gβγ W Deng, AN Bukiya, AA Rodríguez-Menchaca, Z Zhang, CM Baumgarten, ... Journal of Biological Chemistry 287 (7), 4925-4935, 2012 | 42 | 2012 |
| Block of HERG channels by berberine: mechanisms of voltage-and state-dependence probed with site-directed mutant channels A Rodriguez-Menchaca, T Ferrer-Villada, J Lara, D Fernandez, ... Journal of cardiovascular pharmacology 47 (1), 21-29, 2006 | 41 | 2006 |
| Revealing the activation pathway for TMEM16A chloride channels from macroscopic currents and kinetic models JA Contreras-Vite, S Cruz-Rangel, JJ De Jesús-Pérez, IAA Figueroa, ... Pflügers Archiv-European Journal of Physiology 468, 1241-1257, 2016 | 34 | 2016 |
| S(+)amphetamine induces a persistent leak in the human dopamine transporter: molecular stent hypothesis AA Rodriguez‐Menchaca, E Solis Jr, K Cameron, LJ De Felice British journal of pharmacology 165 (8), 2749-2757, 2012 | 33 | 2012 |
| Extracellular protons enable activation of the calcium‐dependent chloride channel TMEM16A S Cruz‐Rangel, JJ De Jesús‐Pérez, IA Aréchiga‐Figueroa, ... The Journal of Physiology 595 (5), 1515-1531, 2017 | 27 | 2017 |
| Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and … A Rosenhouse-Dantsker, S Noskov, H Han, SK Adney, QY Tang, ... Journal of Biological Chemistry 287 (48), 40266-40278, 2012 | 27* | 2012 |
| The antimalarial drug mefloquine inhibits cardiac inward rectifier K+ channels: evidence for interference in PIP2-channel interaction A López-Izquierdo, D Ponce-Balbuena, EG Moreno-Galindo, ... Journal of cardiovascular pharmacology 57 (4), 407-415, 2011 | 27 | 2011 |
| Inhibition of cardiac HERG potassium channels by antidepressant maprotiline T Ferrer-Villada, RA Navarro-Polanco, AA Rodríguez-Menchaca, ... European journal of pharmacology 531 (1-3), 1-8, 2006 | 25 | 2006 |
| Regulation of Kv2. 1 channel inactivation by phosphatidylinositol 4, 5-bisphosphate M Delgado-Ramírez, JJ De Jesús-Pérez, IA Aréchiga-Figueroa, J Arreola, ... Scientific reports 8 (1), 1769, 2018 | 23 | 2018 |
| Chloroquine inhibits tumor-related Kv10. 1 channel and decreases migration of MDA-MB-231 breast cancer cells in vitro B Valdés-Abadía, R Morán-Zendejas, JM Rangel-Flores, ... European Journal of Pharmacology 855, 262-266, 2019 | 21 | 2019 |
| Mechanisms for Kir channel inhibition by quinacrine: acute pore block of Kir2.x channels and interference in PIP2 interaction with Kir2.x and Kir6.2 channels A López-Izquierdo, IA Aréchiga-Figueroa, EG Moreno-Galindo, ... Pflügers Archiv-European Journal of Physiology 462, 505-517, 2011 | 21 | 2011 |
| Chloroquine blocks the Kir4. 1 channels by an open-pore blocking mechanism LG Marmolejo-Murillo, IA Aréchiga-Figueroa, EG Moreno-Galindo, ... European journal of pharmacology 800, 40-47, 2017 | 19 | 2017 |
| Kv1. 5 open channel block by the antiarrhythmic drug disopyramide: molecular determinants of block IA Aréchiga, GF Barrio-Echavarria, AA Rodríguez-Menchaca, ... Journal of pharmacological sciences 108 (1), 49-55, 2008 | 17 | 2008 |
| Molecular mechanisms of chloroquine inhibition of heterologously expressed Kir6. 2/SUR2A channels D Ponce-Balbuena, AA Rodríguez-Menchaca, A López-Izquierdo, ... Molecular pharmacology 82 (5), 803-813, 2012 | 16 | 2012 |
| Regulation of Kv7. 2/Kv7. 3 channels by cholesterol: Relevance of an optimum plasma membrane cholesterol content M Delgado-Ramírez, S Sánchez-Armass, U Meza, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (5), 1242-1251, 2018 | 15 | 2018 |
Jose A. Sanchez-ChapulaProfessor Universidad de ColimaVerified email at ucol.mx
