MASH suite pro: a comprehensive software tool for top-down proteomics W Cai, H Guner, ZR Gregorich, AJ Chen, S Ayaz-Guner, Y Peng, ... Molecular & Cellular Proteomics 15 (2), 703-714, 2016 | 139 | 2016 |
Top-down proteomics of large proteins up to 223 kDa enabled by serial size exclusion chromatography strategy W Cai, T Tucholski, B Chen, AJ Alpert, S McIlwain, T Kohmoto, S Jin, Y Ge Analytical chemistry 89 (10), 5467-5475, 2017 | 130 | 2017 |
Top-down proteomics reveals concerted reductions in myofilament and Z-disc protein phosphorylation after acute myocardial infarction Y Peng, ZR Gregorich, SG Valeja, H Zhang, W Cai, YC Chen, H Guner, ... Molecular & Cellular Proteomics 13 (10), 2752-2764, 2014 | 116 | 2014 |
Top-down proteomics: technology advancements and applications to heart diseases W Cai, TM Tucholski, ZR Gregorich, Y Ge Expert review of proteomics 13 (8), 717-730, 2016 | 107 | 2016 |
MASH Suite: a user-friendly and versatile software interface for high-resolution mass spectrometry data interpretation and visualization H Guner, PL Close, W Cai, H Zhang, Y Peng, ZR Gregorich, Y Ge Journal of The American Society for Mass Spectrometry 25 (3), 464-470, 2014 | 94 | 2014 |
Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics T Tucholski, W Cai, ZR Gregorich, EF Bayne, SD Mitchell, SJ McIlwain, ... Proceedings of the National Academy of Sciences 117 (40), 24691-24700, 2020 | 76 | 2020 |
Specific enrichment of phosphoproteins using functionalized multivalent nanoparticles L Hwang, S Ayaz-Guner, ZR Gregorich, W Cai, SG Valeja, S Jin, Y Ge Journal of the American Chemical Society 137 (7), 2432-2435, 2015 | 70 | 2015 |
An unbiased proteomics method to assess the maturation of human pluripotent stem cell–derived cardiomyocytes W Cai, J Zhang, WJ de Lange, ZR Gregorich, H Karp, ET Farrell, ... Circulation research 125 (11), 936-953, 2019 | 68 | 2019 |
Top-down targeted proteomics reveals decrease in myosin regulatory light-chain phosphorylation that contributes to sarcopenic muscle dysfunction ZR Gregorich, Y Peng, W Cai, Y Jin, L Wei, AJ Chen, SH McKiernan, ... Journal of proteome research 15 (8), 2706-2716, 2016 | 53 | 2016 |
Coupling functionalized cobalt ferrite nanoparticle enrichment with online LC/MS/MS for top-down phosphoproteomics B Chen, L Hwang, W Ochowicz, Z Lin, TM Guardado-Alvarez, W Cai, ... Chemical science 8 (6), 4306-4311, 2017 | 40 | 2017 |
Novel sarcopenia-related alterations in sarcomeric protein post-translational modifications (PTMs) in skeletal muscles identified by top-down proteomics L Wei, ZR Gregorich, Z Lin, W Cai, Y Jin, SH McKiernan, S McIlwain, ... Molecular & Cellular Proteomics 17 (1), 134-145, 2018 | 37 | 2018 |
Monophosphorylation of cardiac troponin-I at Ser-23/24 is sufficient to regulate cardiac myofibrillar Ca2+ sensitivity and calpain-induced proteolysis A Martin-Garrido, BJ Biesiadecki, HE Salhi, Y Shaifta, CG Dos Remedios, ... Journal of Biological Chemistry 293 (22), 8588-8599, 2018 | 36 | 2018 |
Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry ZR Gregorich, W Cai, Z Lin, AJ Chen, Y Peng, T Kohmoto, Y Ge Journal of molecular and cellular cardiology 107, 13-21, 2017 | 35 | 2017 |
Simultaneous Quantification of Protein Expression and Modifications by Top-down Targeted Proteomics: A Case of the Sarcomeric Subproteome*[S] Z Lin, L Wei, W Cai, Y Zhu, T Tucholski, SD Mitchell, W Guo, SP Ford, ... Molecular & Cellular Proteomics 18 (3), 594-605, 2019 | 31 | 2019 |
Complete characterization of cardiac myosin heavy chain (223 kDa) enabled by size-exclusion chromatography and middle-down mass spectrometry Y Jin, L Wei, W Cai, Z Lin, Z Wu, Y Peng, T Kohmoto, RL Moss, Y Ge Analytical chemistry 89 (9), 4922-4930, 2017 | 31 | 2017 |
Epigenetic priming of human pluripotent stem cell-derived cardiac progenitor cells accelerates cardiomyocyte maturation M Biermann, W Cai, D Lang, J Hermsen, L Profio, Y Zhou, A Czirok, ... Stem Cells 37 (7), 910-923, 2019 | 30 | 2019 |
Impact of phosphorylation on the mass spectrometry quantification of intact phosphoproteins Z Wu, TN Tiambeng, W Cai, B Chen, Z Lin, ZR Gregorich, Y Ge Analytical chemistry 90 (8), 4935-4939, 2018 | 26 | 2018 |
Quantitative proteomics and immunohistochemistry reveal insights into cellular and molecular processes in the infarct border zone one month after myocardial infarction L Yang, ZR Gregorich, W Cai, P Zhang, B Young, Y Gu, J Zhang, Y Ge Journal of proteome research 16 (5), 2101-2112, 2017 | 26 | 2017 |
The HCM-linked W792R mutation in cardiac myosin-binding protein C reduces C6 FnIII domain stability DF Smelter, WJ De Lange, W Cai, Y Ge, JC Ralphe American Journal of Physiology-Heart and Circulatory Physiology 314 (6 …, 2018 | 25 | 2018 |
Temperature-sensitive sarcomeric protein post-translational modifications revealed by top-down proteomics W Cai, ZL Hite, B Lyu, Z Wu, Z Lin, ZR Gregorich, AE Messer, SJ McIlwain, ... Journal of molecular and cellular cardiology 122, 11-22, 2018 | 18 | 2018 |