Convenient and inexpensive procedure for oxidation of secondary alcohols to ketones RV Stevens, KT Chapman, HN Weller The Journal of Organic Chemistry 45 (10), 2030-2032, 1980 | 235 | 1980 |
Apparatus for synthesis of multiple organic compounds with pinch valve block W Ruediger, W Li, JW Allen Jr, HN Weller III US Patent 6,432,366, 2002 | 127 | 2002 |
Development of Highly Potent Inhibitors of Ras Farnesyltransferase Possessing Cellular and in Vivo Activity K Leftheris, T Kline, GD Vite, YH Cho, RS Bhide, DV Patel, MM Patel, ... Journal of medicinal chemistry 39 (1), 224-236, 1996 | 102 | 1996 |
High throughput analysis and purification in support of automated parallel synthesis HN Weller, MG Young, SJ Michalczyk, GH Reitnauer, RS Cooley, ... Molecular Diversity 3, 61-70, 1997 | 96 | 1997 |
Phosphinyl acid-based bisubstrate analog inhibitors of farnesyl protein transferase DV Patel, EM Gordon, RJ Schmidt, HN Weller, MG Young, R Zahler, ... Journal of medicinal chemistry 38 (3), 435-442, 1995 | 94 | 1995 |
Quinoxaline N-oxide containing potent angiotensin II receptor antagonists: synthesis, biological properties, and structure-activity relationships KS Kim, L Qian, JE Bird, KEJ Dickinson, S Moreland, TR Schaeffer, ... Journal of medicinal chemistry 36 (16), 2335-2342, 1993 | 89 | 1993 |
Peptidomimetic synthesis: a novel, highly stereoselective route to substituted Freidinger lactams JA Robl, MP Cimarusti, LM Simpkins, HN Weller, YY Pan, M Malley, ... Journal of the American Chemical Society 116 (6), 2348-2355, 1994 | 82 | 1994 |
N-heterocyclic alcohol renin inhibitors DE Ryono, HN Weller III US Patent 4,885,292, 1989 | 71 | 1989 |
N-morpholino derivatives and their use as anti-hypertensive agents HN Weller III, DE Ryono US Patent 5,055,466, 1991 | 66 | 1991 |
Parallel chemistry reactor with interchangeable vessel carrying inserts W Ruediger, AE Rubin, A Bertok, VW Rosso, J Nolfo, HN Weller US Patent 6,893,613, 2005 | 64 | 2005 |
Apparatus for synthesis of multiple organic compounds with pinch valve block W Ruediger, W Li, JW Allen Jr, HN Weller III US Patent 5,961,925, 1999 | 64 | 1999 |
Thermal rearrangements of spiro [4.4] nonapolyenes. Unusually rapid 1, 5-vinyl migration MF Semmelhack, HN Weller, JS Foos Journal of the American Chemical Society 99 (1), 292-294, 1977 | 55 | 1977 |
Purification of combinatorial libraries HN Weller Molecular diversity 4, 47-52, 1998 | 52 | 1998 |
A high‐throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen K Kieltyka, J Zhang, S Li, M Vath, C Baglieri, C Ferraro, TA Zvyaga, ... Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2009 | 46 | 2009 |
Application of lean manufacturing concepts to drug discovery: rapid analogue library synthesis HN Weller, DS Nirschl, EW Petrillo, MA Poss, CJ Andres, CL Cavallaro, ... Journal of Combinatorial Chemistry 8 (5), 664-669, 2006 | 45 | 2006 |
Non-peptidic angiotensin-II-receptor-antagonists HN Weller III US Patent 5,378,704, 1995 | 37 | 1995 |
Quinazolinone inhibitors of cGMP phosphodiesterase JE Macor, DP Rotella, HN Weller III, DW Cushman, JP Yevich US Patent 6,087,368, 2000 | 34 | 2000 |
Comparison of chromatographic techniques for diastereomer separation of a diverse set of drug-like compounds K Ebinger, HN Weller Journal of Chromatography A 1272, 150-154, 2013 | 33 | 2013 |
Ketomethyldipeptides I. A new class of angiotensin converting enzyme inhibitors S Natarajan, EM Gordon, EF Sabo, JD Godfrey, HN Weller, J Pluščec, ... Biochemical and biophysical research communications 124 (1), 141-147, 1984 | 33 | 1984 |
Approach to improve compound recovery in a high‐throughput Caco‐2 permeability assay supported by liquid chromatography–tandem mass spectrometry X Cai, A Walker, C Cheng, A Paiva, Y Li, J Kolb, J Herbst, W Shou, ... Journal of pharmaceutical sciences 101 (8), 2755-2762, 2012 | 32 | 2012 |