关注
Mohd Waseem Akhtar
Mohd Waseem Akhtar
Sanford Burnham Prebys Medical Discover Institute
在 sbpdiscovery.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss
M Talantova, S Sanz-Blasco, X Zhang, P Xia, MW Akhtar, S Okamoto, ...
Proceedings of the National Academy of Sciences 110 (27), E2518-E2527, 2013
6322013
Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss
M Talantova, S Sanz-Blasco, X Zhang, P Xia, MW Akhtar, S Okamoto, ...
Proceedings of the National Academy of Sciences 110 (27), E2518-E2527, 2013
6302013
Isogenic human iPSC Parkinson’s model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription
SD Ryan, N Dolatabadi, SF Chan, X Zhang, MW Akhtar, J Parker, ...
Cell 155 (6), 1351-1364, 2013
4792013
Aberrant protein s-nitrosylation in neurodegenerative diseases
T Nakamura, S Tu, MW Akhtar, CR Sunico, S Okamoto, SA Lipton
Neuron 78 (4), 596-614, 2013
3672013
An essential role for histone deacetylase 4 in synaptic plasticity and memory formation
MS Kim, MW Akhtar, M Adachi, M Mahgoub, R Bassel-Duby, ET Kavalali, ...
Journal of Neuroscience 32 (32), 10879-10886, 2012
2602012
Histone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function
MW Akhtar, J Raingo, ED Nelson, RL Montgomery, EN Olson, ET Kavalali, ...
Journal of Neuroscience 29 (25), 8288-8297, 2009
1812009
Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases
T Nakamura, OA Prikhodko, E Pirie, S Nagar, MW Akhtar, CK Oh, ...
Neurobiology of disease 84, 99-108, 2015
1522015
In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival
MW Akhtar, MS Kim, M Adachi, MJ Morris, X Qi, JA Richardson, ...
PloS one 7 (4), e34863, 2012
1432012
Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation
MW Akhtar, S Sanz-Blasco, N Dolatabadi, J Parker, K Chon, MS Lee, ...
Nature Communications 7 (10242), 2016
1172016
NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism
S Tu, MW Akhtar, RM Escorihuela, A Amador-Arjona, V Swarup, J Parker, ...
Nature communications 8 (1), 1488, 2017
862017
α-Synuclein oligomers induce glutamate release from astrocytes and excessive extrasynaptic NMDAR activity in neurons, thus contributing to synapse loss
D Trudler, S Sanz-Blasco, YS Eisele, S Ghatak, K Bodhinathan, ...
Journal of Neuroscience 41 (10), 2264-2273, 2021
712021
Differential effects of synaptic and extrasynaptic NMDA receptors on Aβ-induced nitric oxide production in cerebrocortical neurons
E Molokanova, MW Akhtar, S Sanz-Blasco, T Nakamura, SI Okamoto, ...
Biophysical Journal 106 (2), 152a, 2014
712014
Redox regulation of protein function via cysteine S-nitrosylation and its relevance to neurodegenerative diseases
MW Akhtar, CR Sunico, T Nakamura, SA Lipton
International journal of cell biology 2012, 2012
602012
Oligomeric Hsp33 with enhanced chaperone activity: gel filtration, cross-linking, and small angle x-ray scattering (SAXS) analysis
MW Akhtar, V Srinivas, B Raman, T Ramakrishna, T Inobe, K Maki, M Arai, ...
Journal of Biological Chemistry 279 (53), 55760-55769, 2004
312004
ATM-dependent phosphorylation of MEF2D promotes neuronal survival after DNA damage
SF Chan, S Sances, LM Brill, S Okamoto, R Zaidi, SR McKercher, ...
Journal of Neuroscience 34 (13), 4640-4653, 2014
272014
Combating oxidative/nitrosative stress with electrophilic counterattack strategies
T Satoh, MW Akhtar, SA Lipton
Oxidative stress and redox regulation, 277-307, 2013
92013
Effect of sparfloxacin and terfenadine combination on QT-intervals at various RR-intervals
M AKHTAR, N Saha, A Roy, KK Pillai
Indian journal of pharmacology 34 (4), 264-268, 2002
32002
Ozanimod (RPC1063) is potentially neuroprotective through direct CNS effects
KR Meadows, JV Selkirk, MW Akhtar, C Hutton, GJ Opiteck, FL Scott
MULTIPLE SCLEROSIS JOURNAL 23, 624-624, 2017
22017
Ozanimod (RPC1063) Potentially Confers Neuroprotective Benefit through Modulation of S1P1R on Astrocytes
KRT Meadows, MW Akhtar, C Villescaz, B Clemons, C Lopez, ...
ACTRIMS Forum 2018, 2018
12018
Ozanimod (RPC1063) Preserves Central Nervous System (CNS) Tissue in Rodents by Reducing Neuronal Breaks in Vivo and Modulating Astrocyte Activity in Vitro (P5. 027)
KT Meadows, MW Akhtar, M Brand, C Villescaz, B Clemons, C Lopez, ...
Neurology 90 (15 Supplement), 2018
2018
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