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Flávia Castro
Flávia Castro
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Email confirmado em i3s.up.pt
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Interferon-gamma at the crossroads of tumor immune surveillance or evasion
F Castro, AP Cardoso, RM Gonçalves, K Serre, MJ Oliveira
Frontiers in immunology 9, 847, 2018
10942018
Type I IFN inhibits alternative macrophage activation during Mycobacterium tuberculosis infection and leads to enhanced protection in the absence of IFN-γ signaling
L Moreira-Teixeira, J Sousa, FW McNab, E Torrado, F Cardoso, ...
The Journal of Immunology 197 (12), 4714-4726, 2016
952016
Anti-inflammatory Chitosan/Poly-γ-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc
GQ Teixeira, CL Pereira, F Castro, JR Ferreira, M Gomez-Lazaro, ...
Acta Biomaterialia 42, 168-179, 2016
832016
Chitosan/γ-PGA nanoparticles-based immunotherapy as adjuvant to radiotherapy in breast cancer
F Castro, ML Pinto, CL Pereira, K Serre, MA Barbosa, K Vermaelen, ...
Biomaterials 257, 120218, 2020
682020
An interferon-γ-delivery system based on chitosan/poly (γ-glutamic acid) polyelectrolyte complexes modulates macrophage-derived stimulation of cancer cell invasion in vitro
AP Cardoso, RM Goncalves, JC Antunes, ML Pinto, AT Pinto, F Castro, ...
Acta biomaterialia 23, 157-171, 2015
592015
Pro-inflammatory chitosan/poly (γ-glutamic acid) nanoparticles modulate human antigen-presenting cells phenotype and revert their pro-invasive capacity
F Castro, ML Pinto, AM Silva, CL Pereira, GQ Teixeira, M Gomez-Lazaro, ...
Acta Biomaterialia 63, 96-109, 2017
552017
MISpheroID: a knowledgebase and transparency tool for minimum information in spheroid identity
A Peirsman, E Blondeel, T Ahmed, J Anckaert, D Audenaert, T Boterberg, ...
Nature methods 18 (11), 1294-1303, 2021
492021
Advances on erythrocyte-mimicking nanovehicles to overcome barriers in biological microenvironments
F Castro, C Martins, MJ Silveira, RP Moura, CL Pereira, B Sarmento
Advanced Drug Delivery Reviews, 2021
412021
Advances on colorectal cancer 3D models: The needed translational technology for nanomedicine screening
F Castro, CL Pereira, MH Macedo, A Almeida, MJ Silveira, S Dias, ...
Advanced Drug Delivery Reviews 175, 113824, 2021
382021
Chitosan/poly (γ-glutamic acid) nanoparticles incorporating IFN-γ for immune response modulation in the context of colorectal cancer
F Castro, ML Pinto, R Almeida, F Pereira, AM Silva, CL Pereira, ...
Biomaterials science 7 (8), 3386-3403, 2019
382019
p28-functionalized PLGA nanoparticles loaded with gefitinib reduce tumor burden and metastases formation on lung cancer
AR Garizo, F Castro, C Martins, A Almeida, TP Dias, F Fernardes, ...
Journal of Controlled Release 337, 329-342, 2021
372021
The immunosuppressive and pro-tumor functions of CCL18 at the tumor microenvironment
AP Cardoso, ML Pinto, F Castro, ÂM Costa, Â Marques-Magalhães, ...
Cytokine & Growth Factor Reviews, 2021
332021
Myeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control
F Cardoso, F Castro, L Moreira-Teixeira, J Sousa, E Torrado, R Silvestre, ...
PLoS One 10 (7), e0131904, 2015
252015
Immunomodulatory potential of Chitosan-based materials for cancer therapy: a systematic review of in vitro, in vivo and clinical studies
BV Lima, MJ Oliveira, MA Barbosa, RM Gonçalves, F Castro
Biomaterials Science, 2021
222021
Oral delivery of camptothecin-loaded multifunctional chitosan-based micelles is effective in reduce colorectal cancer
A Almeida, F Castro, C Resende, M Lúcio, SJ Schwartz, B Sarmento
Journal of Controlled Release 349, 731-743, 2022
152022
Reprogramming of tumor-associated macrophages by polyaniline-coated iron oxide nanoparticles applied to treatment of breast cancer
C Nascimento, F Castro, M Domingues, A Lage, É Alves, R de Oliveira, ...
International Journal of Pharmaceutics 636, 122866, 2023
102023
Harnessing chitosan and poly-(γ-glutamic acid)-based biomaterials towards cancer immunotherapy
BV Lima, MJ Oliveira, MA Barbosa, RM Goncalves, F Castro
Materials Today Advances 15, 100252, 2022
82022
Nanotherapeutics in Women's Health Emerging Nanotechnologies for Triple‐Negative Breast Cancer Treatment
S Torres Quintas, A Canha‐Borges, MJ Oliveira, B Sarmento, F Castro
Small, 2300666, 2023
72023
Immunomodulatory nanomedicine for colorectal cancer treatment: a landscape to be explored?
MJ Silveira, F Castro, MJ Oliveira, B Sarmento
Biomaterials Science, 2021
72021
Hypoxia and Macrophages Act in Concert Towards a Beneficial Outcome in Colon Cancer
F Martins, R Oliveira, B Cavadas, F Pinto, AP Cardoso, F Castro, B Sousa, ...
Cancers 12 (4), 818, 2020
72020
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