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Md Suhail Alam
Md Suhail Alam
Lead Scientist, Spark Therapeutics, PA, USA
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Cited by
Cited by
Year
Studies on structural and functional divergence among seven WhiB proteins of Mycobacterium tuberculosis H37Rv
MS Alam, SK Garg, P Agrawal
The FEBS journal 276 (1), 76-93, 2009
1012009
Crystal structure of full-length Mycobacterium tuberculosis H37Rv glycogen branching enzyme: Insights of N-terminal β-sandwich in substrate specificity and enzymatic activity
K Pal, S Kumar, S Sharma, SK Garg, MS Alam, HE Xu, P Agrawal, ...
Journal of biological chemistry 285 (27), 20897-20903, 2010
912010
Molecular function of WhiB4/Rv3681c of Mycobacterium tuberculosis H37Rv: a [4Fe−4S] cluster co‐ordinating protein disulphide reductase
MS Alam, SK Garg, P Agrawal
Molecular microbiology 63 (5), 1414-1431, 2007
902007
Chronic administration of an HDAC inhibitor treats both neurological and systemic Niemann-Pick type C disease in a mouse model
MS Alam, M Getz, K Haldar
Science translational medicine 8 (326), 326ra23-326ra23, 2016
822016
Expression and characterization of α-(1, 4)-glucan branching enzyme Rv1326c of Mycobacterium tuberculosis H37Rv
SK Garg, MS Alam, KVR Kishan, P Agrawal
Protein expression and purification 51 (2), 198-208, 2007
612007
Redox biology of Mycobacterium tuberculosis H37Rv: protein-protein interaction between GlgB and WhiB1 involves exchange of thiol-disulfide
S Garg, MS Alam, R Bajpai, KVR Kishan, P Agrawal
BMC biochemistry 10, 1-12, 2009
512009
Genomic expression analyses reveal lysosomal innate-immunity proteins as disease correlates in murine models of a lysosomal storage disorder
S Alam, M Getz, J Shin, S Yi, P Velázquez, K Haldar
Molecular Genetics and Metabolism 108 (2), S18, 2012
482012
Plasma signature of neurological disease in the monogenetic disorder Niemann-Pick Type C
MS Alam, M Getz, S Yi, J Kurkewich, I Safeukui, K Haldar
Journal of Biological Chemistry 289 (12), 8051-8066, 2014
362014
Characterization of Mycobacterium tuberculosis WhiB1/Rv3219 as a protein disulfide reductase
SK Garg, MS Alam, V Soni, KVR Kishan, P Agrawal
Protein expression and purification 52 (2), 422-432, 2007
352007
Pluronic based β-cyclodextrin polyrotaxanes for treatment of Niemann-Pick Type C disease
CJ Collins, BP Loren, MS Alam, Y Mondjinou, JL Skulsky, CR Chaplain, ...
Scientific reports 7 (1), 46737, 2017
332017
WhiB2/Rv3260c, a cell division‐associated protein of Mycobacterium tuberculosis H37Rv, has properties of a chaperone
M Konar, MS Alam, C Arora, P Agrawal
The FEBS journal 279 (15), 2781-2792, 2012
312012
Matrix-assisted refolding and redox properties of WhiB3/Rv3416 of Mycobacterium tuberculosis H37Rv
MS Alam, P Agrawal
Protein expression and purification 61 (1), 83-91, 2008
152008
Interaction of Mycobacterium tuberculosis RshA and SigH Is Mediated by Salt Bridges
S Kumar, S Badireddy, K Pal, S Sharma, C Arora, SK Garg, MS Alam, ...
Public Library of Science 7 (8), e43676, 2012
142012
Large scale analyses of genotype-phenotype relationships of glycine decarboxylase mutations and neurological disease severity
J Farris, B Calhoun, MS Alam, S Lee, K Haldar
PLoS computational biology 16 (5), e1007871, 2020
132020
Case report: a synonymous VHL mutation (c.414A > G, p.Pro138Pro) causes pathogenic familial hemangioblastoma through dysregulated splicing
F Liu, B Calhoun, MS Alam, M Sun, X Wang, C Zhang, K Haldar, X Lu
BMC medical genetics 21, 1-6, 2020
82020
Tolerance of chronic HDACi treatment for neurological, visceral and lung Niemann-Pick Type C disease in mice
MS Alam, B Cooper, JD Farris, K Haldar
Scientific Reports 8 (1), 3875, 2018
72018
Genomic analyses of glycine decarboxylase neurogenic mutations yield a large-scale prediction model for prenatal disease
J Farris, MS Alam, AM Rajashekara, K Haldar
PLoS Genetics 17 (2), e1009307, 2021
32021
Detection of Niemann-Pick disease comprising detection of lysozyme and cathepsins
K Haldar, MS Alam
US Patent 10,597,696, 2020
32020
Composition and method for the treatment of neurological diseases and cerebral injury
K Haldar, MS Alam
US Patent App. 16/544,783, 2020
22020
Plasma markers to distinguish brain and liver inflammation in a lysosomal disorder
MS Alam, M Getz, S Yi, J Kurkewich, I Safeukui, K Haldar
Molecular Genetics and Metabolism 2 (111), S18, 2014
12014
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