Optimizing hydroxychloroquine dosing for patients with COVID‐19: an integrative modeling approach for effective drug repurposing M Garcia‐Cremades, BP Solans, E Hughes, JP Ernest, E Wallender, ... Clinical Pharmacology & Therapeutics 108 (2), 253-263, 2020 | 129 | 2020 |
Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: combined data from two prospective observational studies AJ Garcia-Prats, HS Schaaf, HR Draper, M Garcia-Cremades, J Winckler, ... PLoS medicine 16 (4), e1002789, 2019 | 46 | 2019 |
Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens ND Walter, SEM Born, GT Robertson, M Reichlen, C Dide-Agossou, ... Nature communications 12 (1), 2899, 2021 | 44 | 2021 |
Predicting tumour growth and its impact on survival in gemcitabine-treated patients with advanced pancreatic cancer M Garcia-Cremades, C Pitou, PW Iversen, IF Troconiz European Journal of Pharmaceutical Sciences 115, 296-303, 2018 | 15 | 2018 |
Emerging therapeutics, technologies, and drug development strategies to address patient nonadherence and improve tuberculosis treatment M Garcia-Cremades, BP Solans, N Strydom, B Vrijens, GC Pillai, ... Annual Review of Pharmacology and Toxicology 62, 197-210, 2022 | 14 | 2022 |
Characterizing HIV-preventive, plasma tenofovir concentrations—a pooled participant-level data analysis from human immunodeficiency virus preexposure prophylaxis clinical trials M Garcia-Cremades, K Vučićević, CW Hendrix, P Jayachandran, ... Clinical Infectious Diseases 75 (11), 1873-1882, 2022 | 13 | 2022 |
Systematic modeling and design evaluation of unperturbed tumor dynamics in xenografts ZP Parra-Guillen, V Mangas-Sanjuan, M Garcia-Cremades, IF Troconiz, ... Journal of Pharmacology and Experimental Therapeutics 366 (1), 96-104, 2018 | 12 | 2018 |
Combination of Mycobacterium tuberculosis RS ratio and CFU improves the ability of murine efficacy experiments to distinguish between drug treatments C Dide-Agossou, AA Bauman, ME Ramey, K Rossmassler, R Al Mubarak, ... Antimicrobial agents and chemotherapy 66 (4), e02310-21, 2022 | 11 | 2022 |
Oxypurinol pharmacokinetics and pharmacodynamics in healthy volunteers: Influence of BCRP Q141K polymorphism and patient characteristics B Vora, DJ Brackman, L Zou, M Garcia‐Cremades, M Sirota, RM Savic, ... Clinical and translational science 14 (4), 1431-1443, 2021 | 11 | 2021 |
Characterizing gemcitabine effects administered as single agent or combined with carboplatin in mice pancreatic and ovarian cancer xenografts: a semimechanistic pharmacokinetic … M Garcia-Cremades, C Pitou, PW Iversen, IF Troconiz Journal of Pharmacology and Experimental Therapeutics 360 (3), 445-456, 2017 | 11 | 2017 |
Clinical pharmacokinetics of oral sodium selenite and dosing implications in the treatment of patients with metastatic cancer P Jayachandran, SJ Knox, M Garcia-Cremades, RM Savić Drugs in R&D 21, 169-178, 2021 | 5 | 2021 |
Translational framework predicting tumour response in gemcitabine-treated patients with advanced pancreatic and ovarian cancer from xenograft studies M Garcia-Cremades, C Pitou, PW Iversen, IF Troconiz The AAPS Journal 21, 1-10, 2019 | 5 | 2019 |
Mechanistic Multiscale Pharmacokinetic Model for the Anticancer Drug 2’, 2’‐difluorodeoxycytidine (Gemcitabine) in Pancreatic Cancer M Garcia‐Cremades, N Melillo, IF Troconiz, P Magni Clinical and Translational Science 13 (3), 608-617, 2020 | 4 | 2020 |
A Mechanistic In Vivo/Ex Vivo Pharmacokinetic‐Pharmacodynamic Model of Tenofovir for HIV Prevention P Jayachandran, M Garcia-Cremades, K Vučićević, NN Bumpus, P Anton, ... CPT: pharmacometrics & systems pharmacology 10 (3), 179-187, 2021 | 3 | 2021 |
Population Pharmacokinetic/Pharmacodynamic Modelling of Daptomycin for Schedule Optimization in Patients with Renal Impairment T García-Martínez, MD Bellés-Medall, M García-Cremades, ... Pharmaceutics 14 (10), 2226, 2022 | 2 | 2022 |
Modeling the Probability of HIV Infection over Time in High-Risk Seronegative Participants Receiving Placebo in Five Randomized Double-Blind Placebo-Controlled HIV Pre-Exposure … M Garcia-Cremades, CW Hendrix, P Jayachandran, N Strydom, ... Pharmaceutics 14 (9), 1801, 2022 | 1 | 2022 |
Response to “Quantitative Clinical Pharmacology INPUT to SARS‐CoV‐2 Therapeutics Should be Based on Robust Data” M Garcia‐Cremades, BP Solans, E Hughes, JP Ernest, E Wallender, ... Clinical pharmacology and therapeutics 108 (2), 189, 2020 | | 2020 |