Model‐informed drug development of autologous CAR‐T cell therapy: Strategies to optimize CAR‐T cell exposure leveraging cell kinetic/dynamic modeling AM Mc Laughlin, PA Milligan, C Yee, M Bergstrand CPT: Pharmacometrics & Systems Pharmacology 12 (11), 1577-1590, 2023 | 3 | 2023 |
Caplacizumab model‐based dosing recommendations in pediatric patients with acquired thrombotic thrombocytopenic purpura M Bergstrand, E Hansson, B Delaey, F Callewaert, R De Passos Sousa, ... The Journal of Clinical Pharmacology 62 (3), 409-421, 2022 | 12 | 2022 |
Pharmacokinetic modeling and simulation support for age‐and weight‐adjusted dosing of dabigatran etexilate in children with venous thromboembolism D Röshammar, F Huang, M Albisetti, L Bomgaars, E Chalmers, M Luciani, ... Journal of Thrombosis and Haemostasis 19 (5), 1259-1270, 2021 | 12 | 2021 |
PS1487 EFFECT OF PLASMA EXCHANGE ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF CAPLACIZUMAB L Sargentini, E Hansson, M Bergstrand, F Callewaert, R Sousa HemaSphere 3, 685, 2019 | 1 | 2019 |
PB2249 CAPLACIZUMAB MODEL-BASED DOSING RECOMMENDATIONS IN PEDIATRIC PATIENTS WITH ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA L Sargentini, E Hansson, M Bergstrand, F Callewaert, R Sousa HemaSphere 3 (S1), 1007, 2019 | 1 | 2019 |
Population pharmacokinetic and pharmacodynamic properties of artesunate in patients with artemisinin sensitive and resistant infections in Southern Myanmar JP Lohy Das, MP Kyaw, MH Nyunt, K Chit, KH Aye, MM Aye, MO Karlsson, ... Malaria Journal 17, 1-10, 2018 | 19 | 2018 |
Model‐based prediction of plasma concentration and enterohepatic circulation of total bile acids in humans B Guiastrennec, DP Sonne, M Bergstrand, T Vilsbøll, FK Knop, ... CPT: pharmacometrics & systems pharmacology 7 (9), 603-612, 2018 | 15 | 2018 |
TRANSLATIONAL MODELING OF MINIPIG AND DOG GLUCOSE AND INSULIN DATA ACCURATELY PREDICTS HUMAN INSULIN ACTION FOR MK-2640 BUT NOT ITS GLUCOSE-RESPONSIVE PHARMACOKINETICS. B Kandala, C Fancourt, C Cho, E Carballo-Jane, P Zafian, M Bergstrand, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 103, S71-S71, 2018 | 2 | 2018 |
Population Pharmacokinetic and Pharmacodynamic Properties of Artesunate in Patients with Artemisinin Resistant Infections in Southern Myanmar J Lohy Das, MP Kyaw, M Nyunt, K Chit, K Aye, M Aye, MO Karlsson, ... Malaria Journal 17, 2018 | | 2018 |
An automated sampling importance resampling procedure for estimating parameter uncertainty AG Dosne, M Bergstrand, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 44, 509-520, 2017 | 110 | 2017 |
Population pharmacokinetic and pharmacodynamic modeling of artemisinin resistance in Southeast Asia J Lohy Das, AM Dondorp, F Nosten, AP Phyo, W Hanpithakpong, ... The AAPS Journal 19, 1842-1854, 2017 | 16 | 2017 |
Model averaging for robust assessment of QT prolongation by concentration‐response analysis AG Dosne, M Bergstrand, MO Karlsson, D Renard, G Heimann Statistics in Medicine 36 (24), 3844-3857, 2017 | 7 | 2017 |
Prediction of improved antimalarial chemoprevention with weekly dosing of dihydroartemisinin-piperaquine J Permala, J Tarning, F Nosten, NJ White, MO Karlsson, M Bergstrand Antimicrobial agents and chemotherapy 61 (5), 10.1128/aac. 02491-16, 2017 | 21 | 2017 |
Population pharmacokinetics of ticagrelor and AR-C124910XX in patients with prior myocardial infarction D Röshammar, M Bergstrand, T Andersson, RF Storey, B Hamrén International Journal of Clinical Pharmacology and Therapeutics 55 (5), 416, 2017 | 16 | 2017 |
In Vitro and In Vivo Modeling of Hydroxypropyl Methylcellulose (HPMC) Matrix Tablet Erosion Under Fasting and Postprandial Status B Guiastrennec, E Söderlind, S Richardson, A Peric, M Bergstrand Pharmaceutical research 34, 847-859, 2017 | 17 | 2017 |
Mechanism‐based modeling of gastric emptying rate and gallbladder emptying in response to caloric intake B Guiastrennec, DP Sonne, M Hansen, JI Bagger, A Lund, JF Rehfeld, ... CPT: pharmacometrics & systems pharmacology 5 (12), 692-700, 2016 | 18 | 2016 |
Improving the estimation of parameter uncertainty distributions in nonlinear mixed effects models using sampling importance resampling AG Dosne, M Bergstrand, K Harling, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 43, 583-596, 2016 | 224 | 2016 |
A strategy for residual error modeling incorporating scedasticity of variance and distribution shape AG Dosne, M Bergstrand, MO Karlsson Journal of Pharmacokinetics and Pharmacodynamics 43, 137-151, 2016 | 31 | 2016 |
Meta-analysis of magnetic marker monitoring data to characterize the movement of single unit dosage forms though the gastrointestinal tract under fed and fasting conditions E Hénin, M Bergstrand, W Weitschies, MO Karlsson Pharmaceutical research 33, 751-762, 2016 | 24 | 2016 |
Longitudinal Data Analysis Using Model Averaging: Benefits For Pivotal Clinical Trials, Applied To Rheumatoid Arthritis AG Dosne, B Bieth, M Bergstrand, MO Karlsson, D Renard | | 2016 |