| Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte PWS Hill, HG Leitch, CE Requena, Z Sun, R Amouroux, M Roman-Trufero, ... Nature 555 (7696), 392-396, 2018 | 231 | 2018 |
| USER™ friendly DNA engineering and cloning method by uracil excision J Bitinaite, M Rubino, KH Varma, I Schildkraut, R Vaisvila, R Vaiskunaite Nucleic acids research 35 (6), 1992-2002, 2007 | 220 | 2007 |
| Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes SM Kinney, HG Chin, R Vaisvila, J Bitinaite, Y Zheng, PO Esteve, S Feng, ... Journal of Biological Chemistry 286 (28), 24685-24693, 2011 | 206 | 2011 |
| Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA R Vaisvila, VKC Ponnaluri, Z Sun, BW Langhorst, L Saleh, S Guan, N Dai, ... Genome research 31 (7), 1280-1289, 2021 | 201 | 2021 |
| Discovery and distribution of super‐integrons among Pseudomonads R Vaisvila, RD Morgan, J Posfai, EA Raleigh Molecular microbiology 42 (3), 587-601, 2001 | 157 | 2001 |
| The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target B Wu, J Novelli, J Foster, R Vaisvila, L Conway, J Ingram, M Ganatra, ... PLoS Neglected Tropical Diseases 3 (7), e475, 2009 | 138 | 2009 |
| Cloning and sequence analysis of the genes coding for Eco57l type IV restriction-modification enzymes A Janulaitis, R Vaisvila, A Timinskas, S Klimasauskas, V Butkus Nucleic acids research 20 (22), 6051-6056, 1992 | 74 | 1992 |
| High sensitivity 5-hydroxymethylcytosine detection in Balb/C brain tissue T Davis, R Vaisvila JoVE (Journal of Visualized Experiments), e2661, 2011 | 68 | 2011 |
| Nondestructive enzymatic deamination enables single-molecule long-read amplicon sequencing for the determination of 5-methylcytosine and 5-hydroxymethylcytosine at single-base … Z Sun, R Vaisvila, LM Hussong, B Yan, C Baum, L Saleh, ... Genome Research 31 (2), 291-300, 2021 | 66 | 2021 |
| The eco72IC gene specifies a trans-acting factor which influences expression of both DNA methyltransferase and endonuclease from the Eco72I restriction-modification system A Rimšeliené, R., Vaišvila, R., & Janulaitis Gene, 0 | 65* | |
| Repair of Nucleic Acids for Improved Amplification TC Evans Jr, B Slatko, L Chen, R Vaisvila, C Guan, R Kucera US Patent App. 12/296,827, 2010 | 60 | 2010 |
| Biochemical characterization of a Naegleria TET-like oxygenase and its application in single molecule sequencing of 5-methylcytosine JE Pais, N Dai, E Tamanaha, R Vaisvila, AI Fomenkov, J Bitinaite, Z Sun, ... Proceedings of the National Academy of Sciences 112 (14), 4316-4321, 2015 | 57 | 2015 |
| CAATTG-specific restriction-modification munI genes from Mycoplasma: sequence similarities between R· MunI and R· EcoRI V Siksnys, N Zareckaja, R Vaisvila, A Timinskas, P Stakenas, V Butkus, ... Gene 142 (1), 1-8, 1994 | 47 | 1994 |
| Protein engineering: single or multiple site-directed mutagenesis PC Hsieh, R Vaisvila Enzyme Engineering: Methods and Protocols, 173-186, 2013 | 45 | 2013 |
| EM-seq: detection of DNA methylation at single base resolution from picograms of DNA R Vaisvila, VKC Ponnaluri, Z Sun, BW Langhorst, L Saleh, S Guan, N Dai, ... BioRxiv, 2019.12. 20.884692, 2019 | 41 | 2019 |
| Methods and compositions for discrimination between cytosine and modifications thereof and for methylome analysis R Vaisvila, HE Johnson, S Vainauskas, TB Davis US Patent 9,121,061, 2015 | 36 | 2015 |
| Identification of a gene encoding a DNA invertase-like enzyme adjacent to the PaeR7I restriction-modification system R Vaišvila, G Vilkaitis, A Janulaitis Gene 157 (1-2), 81-84, 1995 | 36 | 1995 |
| Detection and quantification of hydroxymethylated nucleotides in a polynucleotide preparation J Bitinaite, R Vaisvila, S Pradhan, Y Zheng, RJ Roberts, D Cohen-Karni, ... US Patent 9,034,597, 2015 | 34 | 2015 |
| Compositions and methods for analyzing modified nucleotides R Vaisvila, Z Sun, S Guan, L Saleh, L Ettwiller, TB Davis US Patent 10,227,646, 2019 | 29 | 2019 |
| Compositions and methods for analyzing modified nucleotides R Vaisvila, TB Davis, S Guan, Z Sun, L Ettwiller, L Saleh US Patent 10,260,088, 2019 | 23 | 2019 |
