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David S. Roberts
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Novel strategies to address the challenges in top-down proteomics
JA Melby*, DS Roberts*, EJ Larson, KA Brown, EF Bayne, S Jin, Y Ge, ...
Journal of the American Society for Mass Spectrometry 32 (6), 1278-1294, 2021
1232021
Top-down proteomics: challenges, innovations, and applications in basic and clinical research
KA Brown, JA Melby, DS Roberts, Y Ge
Expert Review of Proteomics, 1-15, 2020
872020
MASH explorer: a universal software environment for top-down proteomics
Z Wu, DS Roberts, JA Melby, K Wenger, M Wetzel, Y Gu, SG Ramanathan, ...
Journal of proteome research 19 (9), 3867-3876, 2020
702020
Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Top-Down Mass Spectrometry
DS Roberts†, M Mann, JA Melby, EJ Larson, Y Zhu, AR Brasier, S Jin, ...
Journal of the American Chemical Society 143 (31), 12014–12024, 2021
532021
Nanoproteomics enables proteoform-resolved analysis of low-abundance proteins in human serum
TN Tiambeng*, DS Roberts*, KA Brown, Y Zhu, B Chen, Z Wu, SD Mitchell, ...
Nature communications 11 (1), 1-12, 2020
532020
Ultrafast and Reproducible Proteomics from Small Amounts of Heart Tissue Enabled by Azo and timsTOF Pro
TJ Aballo, DS Roberts, JA Melby, KM Buck, KA Brown, Y Ge
Journal of Proteome Research 20 (8), 4203–4211, 2021
442021
Oriented nanofibrous polymer scaffolds containing protein‐loaded porous silicon generated by spray nebulization
JM Zuidema, T Kumeria, D Kim, J Kang, J Wang, G Hollett, X Zhang, ...
Advanced Materials 30 (12), 1706785, 2018
422018
High-throughput multi-attribute analysis of antibody-drug conjugates enabled by trapped ion mobility spectrometry and top-down mass spectrometry
EJ Larson*, DS Roberts*, JA Melby, KM Buck, Y Zhu, S Zhou, L Han, ...
Analytical chemistry 93 (29), 10013-10021, 2021
322021
Reproducible large-scale synthesis of surface silanized nanoparticles as an enabling nanoproteomics platform: Enrichment of the human heart phosphoproteome
DS Roberts, B Chen, TN Tiambeng, Z Wu, Y Ge, S Jin
Nano Research 12 (6), 1473–1481, 2019
272019
High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms
JA Melby, KA Brown, ZR Gregorich, DS Roberts, EA Chapman, LE Ehlers, ...
Proceedings of the National Academy of Sciences 120 (19), e2222081120, 2023
232023
Distinct core glycan and O-glycoform utilization of SARS-CoV-2 Omicron variant Spike protein RBD revealed by top-down mass spectrometry
DS Roberts†, M Mann, BH Li, D Kim, AR Braiser, S Jin, Y Ge†, ...
Chemical science 13 (36), 10944-10949, 2022
192022
Discovery of RSV-induced BRD4 protein interactions using native immunoprecipitation and parallel accumulation—serial fragmentation (PASEF) mass spectrometry
M Mann, DS Roberts, Y Zhu, Y Li, J Zhou, Y Ge, AR Brasier
Viruses 13 (3), 454, 2021
192021
Functionally integrated top-down proteomics for standardized assessment of human induced pluripotent stem cell-derived engineered cardiac tissues
JA Melby, WJ de Lange, J Zhang, DS Roberts, SD Mitchell, T Tucholski, ...
Journal of proteome research 20 (2), 1424-1433, 2021
182021
Preparation of Photoluminescent Porous Silicon Nanoparticles by High‐Pressure Microfluidization
DS Roberts, D Estrada, N Yagi, EJ Anglin, NA Chan, MJ Sailor
Particle & Particle Systems Characterization 34 (3), 1600326, 2017
182017
Analysis of cardiac troponin proteoforms by top-down mass spectrometry
TN Tiambeng, T Tucholski, Z Wu, Y Zhu, SD Mitchell, DS Roberts, Y Jin, ...
Methods in enzymology 626, 347-374, 2019
152019
One-pot exosome proteomics enabled by a photocleavable surfactant
KM Buck, DS Roberts, TJ Aballo, DR Inman, S Jin, S Ponik, KA Brown, ...
Analytical chemistry 94 (20), 7164-7168, 2022
132022
Necroptosis is associated with Rab27‐independent expulsion of extracellular vesicles containing RIPK3 and MLKL
K Gupta, KA Brown, ML Hsieh, BM Hoover, J Wang, MK Khoury, VSS Pilli, ...
Journal of extracellular vesicles 11 (9), e12261, 2022
122022
Quantum ensembles of silicon nanoparticles: discrimination of static and dynamic photoluminescence quenching processes
G Hollett, DS Roberts, M Sewell, E Wensley, J Wagner, W Murray, A Krotz, ...
The Journal of Physical Chemistry C 123 (29), 17976-17986, 2019
122019
MASH Native: a unified solution for native top-down proteomics data processing
EJ Larson, MR Pergande, ME Moss, KJ Rossler, RK Wenger, B Krichel, ...
Bioinformatics 39 (6), btad359, 2023
112023
Multiomics method enabled by sequential metabolomics and proteomics for human pluripotent stem-cell-derived cardiomyocytes
EF Bayne, AD Simmons, DS Roberts, Y Zhu, TJ Aballo, B Wancewicz, ...
Journal of proteome research 20 (10), 4646-4654, 2021
102021
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