Transferability of genetic risk scores in African populations AB Kamiza, SM Toure, M Vujkovic, T Machipisa, OS Soremekun, C Kintu, ... Nature Medicine 28 (6), 1163-1166, 2022 | 37 | 2022 |
An update on the pharmacological usage of curcumin: has it failed in the drug discovery pipeline? F Olotu, C Agoni, O Soremekun, MES Soliman Cell Biochemistry and Biophysics 78 (3), 267-289, 2020 | 33 | 2020 |
Lipid traits and type 2 diabetes risk in African ancestry individuals: A Mendelian Randomization study O Soremekun, V Karhunen, Y He, S Rajasundaram, B Liu, A Gkatzionis, ... EBioMedicine 78, 2022 | 20 | 2022 |
Metabolic traits and stroke risk in individuals of African ancestry: Mendelian randomization analysis S Fatumo, V Karhunen, T Chikowore, T Sounkou, B Udosen, C Ezenwa, ... Stroke 52 (8), 2680-2684, 2021 | 20 | 2021 |
Exploring the ring potential of 2, 4-diaminopyrimidine derivatives towards the identification of novel caspase-1 inhibitors in Alzheimer’s disease therapy RO Kumi, OS Soremekun, AR Issahaku, C Agoni, FA Olotu, MES Soliman Journal of molecular modeling 26, 1-17, 2020 | 20 | 2020 |
Identification and classification of differentially expressed genes reveal potential molecular signature associated with SARS-CoV-2 infection in lung adenocarcinomal cells OS Soremekun, KF Omolabi, MES Soliman Informatics in medicine unlocked 20, 100384, 2020 | 20 | 2020 |
Recruiting monomer for dimer formation: resolving the antagonistic mechanisms of novel immune check point inhibitors against programmed death ligand-1 in cancer immunotherapy OS Soremekun, FA Olotu, C Agoni, MES Soliman Molecular Simulation 45 (10), 777-789, 2019 | 20 | 2019 |
Thompson loop: opportunities for antitubercular drug design by targeting the weak spot in demethylmenaquinone methyltransferase protein AT Adewumi, OS Soremekun, MB Ajadi, MES Soliman RSC advances 10 (39), 23466-23483, 2020 | 17 | 2020 |
Uganda Genome Resource: a rich research database for genomic studies of communicable and non-communicable diseases in Africa S Fatumo, J Mugisha, OS Soremekun, A Kalungi, R Mayanja, C Kintu, ... Cell Genomics 2 (11), 2022 | 15 | 2022 |
Weak spots inhibition in the Mycobacterium tuberculosis antigen 85C target for antitubercular drug design through selective irreversible covalent inhibitor-SER124 AT Adewumi, A Elrashedy, OS Soremekun, MB Ajadi, MES Soliman Journal of Biomolecular Structure and Dynamics 40 (7), 2934-2954, 2022 | 15 | 2022 |
Drug promiscuity: exploring the polypharmacology potential of 1, 3, 6-trisubstituted 1, 4-diazepane-7-ones as an inhibitor of the ‘god father’of immune checkpoint OS Soremekun, FA Olotu, C Agoni, MES Soliman Computational Biology and Chemistry 80, 433-440, 2019 | 15 | 2019 |
Development of halogenated pyrazolines as selective monoamine oxidase-B Inhibitors: Deciphering via molecular dynamics approach AS Nair, JM Oh, VP Koyiparambath, S Kumar, ST Sudevan, O Soremekun, ... Molecules 26 (11), 3264, 2021 | 13 | 2021 |
The recent application of 3D-QSAR and docking studies to novel HIV-protease inhibitor drug discovery FA Olotu, C Agoni, O Soremekun, MES Soliman Expert Opinion on Drug Discovery 15 (9), 1095-1109, 2020 | 13 | 2020 |
Phytomedicine in disease management: In-silico analysis of the binding affinity of artesunate and azadirachtin for malaria treatment MP Okoh, RK Singla, C Madu, O Soremekun, B Shen Frontiers in Pharmacology 12, 751032, 2021 | 12 | 2021 |
From genomic variation to protein aberration: mutational analysis of single nucleotide polymorphism present in ULBP6 gene and implication in immune response OS Soremekun, MES Soliman Computers in Biology and Medicine 111, 103354, 2019 | 9 | 2019 |
Integrating bioinformatics strategies in cancer immunotherapy: current and future perspectives HN Washah, EY Salifu, O Soremekun, AA Elrashedy, G Munsamy, ... Combinatorial Chemistry & High Throughput Screening 23 (8), 687-698, 2020 | 8 | 2020 |
Same target, different therapeutic outcomes: The case of CAY10471 and fevipiprant on CRTh2 receptor in treatment of allergic rhinitis and asthma AR Issahaku, C Agoni, OS Soremekun, PA Kubi, RO Kumi, FA Olotu, ... Combinatorial Chemistry & High Throughput Screening 22 (8), 521-533, 2019 | 8 | 2019 |
Genome-wide association and mendelian randomization analysis reveal the causal relationship between white blood cell subtypes and asthma in africans O Soremekun, C Soremekun, T Machipisa, M Soliman, O Nashiru, ... Frontiers in genetics 12, 749415, 2021 | 6 | 2021 |
Mutational analysis of p53 gene in cervical cancer and useful polymorphic variants in exons 3 and 4 MA Gbadegesin, OE Omotoso, TAO Oluwasola, CA Okolo, O Soremekun, ... Egyptian Journal of Medical Human Genetics 22, 1-8, 2021 | 6 | 2021 |
Prospecting the therapeutic edge of a novel compound (B12) over berberine in the selective targeting of Retinoid X Receptor in colon cancer TI Subair, OS Soremekun, FA Olotu, MES Soliman Journal of Molecular Modeling 27, 1-12, 2021 | 6 | 2021 |