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Opeyemi S Soremekun
Opeyemi S Soremekun
MRC/UVRI and LSHTM
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Year
Transferability of genetic risk scores in African populations
AB Kamiza, SM Toure, M Vujkovic, T Machipisa, OS Soremekun, C Kintu, ...
Nature Medicine 28 (6), 1163-1166, 2022
372022
An update on the pharmacological usage of curcumin: has it failed in the drug discovery pipeline?
F Olotu, C Agoni, O Soremekun, MES Soliman
Cell Biochemistry and Biophysics 78 (3), 267-289, 2020
332020
Lipid traits and type 2 diabetes risk in African ancestry individuals: A Mendelian Randomization study
O Soremekun, V Karhunen, Y He, S Rajasundaram, B Liu, A Gkatzionis, ...
EBioMedicine 78, 2022
202022
Metabolic traits and stroke risk in individuals of African ancestry: Mendelian randomization analysis
S Fatumo, V Karhunen, T Chikowore, T Sounkou, B Udosen, C Ezenwa, ...
Stroke 52 (8), 2680-2684, 2021
202021
Exploring the ring potential of 2, 4-diaminopyrimidine derivatives towards the identification of novel caspase-1 inhibitors in Alzheimer’s disease therapy
RO Kumi, OS Soremekun, AR Issahaku, C Agoni, FA Olotu, MES Soliman
Journal of molecular modeling 26, 1-17, 2020
202020
Identification and classification of differentially expressed genes reveal potential molecular signature associated with SARS-CoV-2 infection in lung adenocarcinomal cells
OS Soremekun, KF Omolabi, MES Soliman
Informatics in medicine unlocked 20, 100384, 2020
202020
Recruiting monomer for dimer formation: resolving the antagonistic mechanisms of novel immune check point inhibitors against programmed death ligand-1 in cancer immunotherapy
OS Soremekun, FA Olotu, C Agoni, MES Soliman
Molecular Simulation 45 (10), 777-789, 2019
202019
Thompson loop: opportunities for antitubercular drug design by targeting the weak spot in demethylmenaquinone methyltransferase protein
AT Adewumi, OS Soremekun, MB Ajadi, MES Soliman
RSC advances 10 (39), 23466-23483, 2020
172020
Uganda Genome Resource: a rich research database for genomic studies of communicable and non-communicable diseases in Africa
S Fatumo, J Mugisha, OS Soremekun, A Kalungi, R Mayanja, C Kintu, ...
Cell Genomics 2 (11), 2022
152022
Weak spots inhibition in the Mycobacterium tuberculosis antigen 85C target for antitubercular drug design through selective irreversible covalent inhibitor-SER124
AT Adewumi, A Elrashedy, OS Soremekun, MB Ajadi, MES Soliman
Journal of Biomolecular Structure and Dynamics 40 (7), 2934-2954, 2022
152022
Drug promiscuity: exploring the polypharmacology potential of 1, 3, 6-trisubstituted 1, 4-diazepane-7-ones as an inhibitor of the ‘god father’of immune checkpoint
OS Soremekun, FA Olotu, C Agoni, MES Soliman
Computational Biology and Chemistry 80, 433-440, 2019
152019
Development of halogenated pyrazolines as selective monoamine oxidase-B Inhibitors: Deciphering via molecular dynamics approach
AS Nair, JM Oh, VP Koyiparambath, S Kumar, ST Sudevan, O Soremekun, ...
Molecules 26 (11), 3264, 2021
132021
The recent application of 3D-QSAR and docking studies to novel HIV-protease inhibitor drug discovery
FA Olotu, C Agoni, O Soremekun, MES Soliman
Expert Opinion on Drug Discovery 15 (9), 1095-1109, 2020
132020
Phytomedicine in disease management: In-silico analysis of the binding affinity of artesunate and azadirachtin for malaria treatment
MP Okoh, RK Singla, C Madu, O Soremekun, B Shen
Frontiers in Pharmacology 12, 751032, 2021
122021
From genomic variation to protein aberration: mutational analysis of single nucleotide polymorphism present in ULBP6 gene and implication in immune response
OS Soremekun, MES Soliman
Computers in Biology and Medicine 111, 103354, 2019
92019
Integrating bioinformatics strategies in cancer immunotherapy: current and future perspectives
HN Washah, EY Salifu, O Soremekun, AA Elrashedy, G Munsamy, ...
Combinatorial Chemistry & High Throughput Screening 23 (8), 687-698, 2020
82020
Same target, different therapeutic outcomes: The case of CAY10471 and fevipiprant on CRTh2 receptor in treatment of allergic rhinitis and asthma
AR Issahaku, C Agoni, OS Soremekun, PA Kubi, RO Kumi, FA Olotu, ...
Combinatorial Chemistry & High Throughput Screening 22 (8), 521-533, 2019
82019
Genome-wide association and mendelian randomization analysis reveal the causal relationship between white blood cell subtypes and asthma in africans
O Soremekun, C Soremekun, T Machipisa, M Soliman, O Nashiru, ...
Frontiers in genetics 12, 749415, 2021
62021
Mutational analysis of p53 gene in cervical cancer and useful polymorphic variants in exons 3 and 4
MA Gbadegesin, OE Omotoso, TAO Oluwasola, CA Okolo, O Soremekun, ...
Egyptian Journal of Medical Human Genetics 22, 1-8, 2021
62021
Prospecting the therapeutic edge of a novel compound (B12) over berberine in the selective targeting of Retinoid X Receptor in colon cancer
TI Subair, OS Soremekun, FA Olotu, MES Soliman
Journal of Molecular Modeling 27, 1-12, 2021
62021
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Articles 1–20