Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma Y Jiang, A Sun, Y Zhao, W Ying, H Sun, X Yang, B Xing, W Sun, L Ren, ... Nature 567, 257–261, 2019 | 629 | 2019 |
Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19 Y Su, D Chen, D Yuan, C Lausted, J Choi, CL Dai, V Voillet, VR Duvvuri, ... Cell 183 (6), 1479-1495. e20, 2020 | 502 | 2020 |
Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion Y Huang, Z Xu, S Xiong, F Sun, G Qin, G Hu, J Wang, L Zhao, YX Liang, ... Nature neuroscience 21 (4), 530-540, 2018 | 467 | 2018 |
Prediction of synergistic anti-cancer drug combinations based on drug target network and drug induced gene expression profiles X Li, Y Xu, H Cui, T Huang, D Wang, B Lian, W Li, G Qin, L Chen, L Xie Artificial intelligence in medicine 83, 35-43, 2017 | 92 | 2017 |
Investigation of lipid metabolism dysregulation and the effects on immune microenvironments in pan-cancer using multiple omics data Y Hao, D Li, Y Xu, J Ouyang, Y Wang, Y Zhang, B Li, L Xie, G Qin BMC Bioinformatics 20 (Suppl 7), 195, 2019 | 91 | 2019 |
Dual extra-retinal origins of microglia in the model of retinal microglia repopulation Y Huang, Z Xu, S Xiong, G Qin, F Sun, J Yang, TF Yuan, L Zhao, K Wang, ... Cell discovery 4 (1), 9, 2018 | 87 | 2018 |
Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding Y Wu, G Qin, F Gao, Y Liu, CJ Vavricka, J Qi, H Jiang, K Yu, GF Gao Scientific reports 3 (1), 1551, 2013 | 71 | 2013 |
Revealing Missing Human Protein Isoforms Based on Ab Initio Prediction, RNA-seq and Proteomics Z Hu, HS Scott, G Qin, G Zheng, X Chu, L Xie, DL Adelson, BE Oftedal, ... Scientific reports 5 (1), 10940, 2015 | 52 | 2015 |
Discovering novel quercetin-3-O-amino acid-esters as a new class of Src tyrosine kinase inhibitors H Huang, Q Jia, J Ma, G Qin, Y Chen, Y Xi, L Lin, W Zhu, J Ding, H Jiang, ... European journal of medicinal chemistry 44 (5), 1982-1988, 2009 | 49 | 2009 |
Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science DR Unni, SAT Moxon, M Bada, M Brush, R Bruskiewich, JH Caufield, ... Clinical and translational science 15 (8), 1848-1855, 2022 | 43 | 2022 |
Biomolecular network-based synergistic drug combination discovery X Li, G Qin, Q Yang, L Chen, L Xie BioMed research international 2016, 2016 | 43 | 2016 |
Long route or shortcut? A molecular dynamics study of traffic of thiocholine within the active-site gorge of acetylcholinesterase Y Xu, JP Colletier, M Weik, G Qin, H Jiang, I Silman, JL Sussman Biophysical journal 99 (12), 4003-4011, 2010 | 37 | 2010 |
Targeting the small-and intermediate-conductance Ca2+-activated potassium channels: The drug-binding pocket at the channel/calmodulin interface M Cui, G Qin, K Yu, MS Bowers, M Zhang Neurosignals 22 (2), 65-78, 2015 | 30 | 2015 |
Conformational transition and energy landscape of ErbB4 activated by neuregulin1β: one microsecond molecular dynamics simulations Y Du, H Yang, Y Xu, X Cang, C Luo, Y Mao, Y Wang, G Qin, X Luo, ... Journal of the American Chemical Society 134 (15), 6720-6731, 2012 | 28 | 2012 |
Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus (A/H1N1)? K Yu, C Luo, G Qin, Z Xu, N Li, H Liu, X Shen, J Ma, Q Wang, C Yang, ... Cell research 19 (10), 1221-1224, 2009 | 23 | 2009 |
Coordinated silencing of the Sp1-mediated long noncoding RNA MEG3 by EZH2 and HDAC3 as a prognostic factor in pancreatic ductal adenocarcinoma T Han, M Zhuo, C Yuan, X Xiao, J Cui, G Qin, L Wang, F Jiao Cancer biology & medicine 17 (4), 953, 2020 | 22 | 2020 |
How does influenza virus a escape from amantadine? G Qin, K Yu, T Shi, C Luo, G Li, W Zhu, H Jiang The Journal of Physical Chemistry B 114 (25), 8487-8493, 2010 | 20 | 2010 |
Progress toward a universal biomedical data translator K Fecho, AT Thessen, SE Baranzini, C Bizon, JJ Hadlock, S Huang, ... Clinical and Translational Science, 2022 | 18 | 2022 |
Exploring the RING-catalyzed ubiquitin transfer mechanism by MD and QM/MM calculations Y Zhen, G Qin, C Luo, H Jiang, K Yu, G Chen PloS one 9 (7), e101663, 2014 | 15 | 2014 |
The structural characterization of tumor fusion genes and proteins D Wang, D Li, G Qin, W Zhang, J Ouyang, M Zhang, L Xie Computational and Mathematical Methods in Medicine 2015, 2015 | 14 | 2015 |