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Guangrong Qin
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Year
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
Y Jiang, A Sun, Y Zhao, W Ying, H Sun, X Yang, B Xing, W Sun, L Ren, ...
Nature 567, 257–261, 2019
6292019
Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19
Y Su, D Chen, D Yuan, C Lausted, J Choi, CL Dai, V Voillet, VR Duvvuri, ...
Cell 183 (6), 1479-1495. e20, 2020
5022020
Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion
Y Huang, Z Xu, S Xiong, F Sun, G Qin, G Hu, J Wang, L Zhao, YX Liang, ...
Nature neuroscience 21 (4), 530-540, 2018
4672018
Prediction of synergistic anti-cancer drug combinations based on drug target network and drug induced gene expression profiles
X Li, Y Xu, H Cui, T Huang, D Wang, B Lian, W Li, G Qin, L Chen, L Xie
Artificial intelligence in medicine 83, 35-43, 2017
922017
Investigation of lipid metabolism dysregulation and the effects on immune microenvironments in pan-cancer using multiple omics data
Y Hao, D Li, Y Xu, J Ouyang, Y Wang, Y Zhang, B Li, L Xie, G Qin
BMC Bioinformatics 20 (Suppl 7), 195, 2019
912019
Dual extra-retinal origins of microglia in the model of retinal microglia repopulation
Y Huang, Z Xu, S Xiong, G Qin, F Sun, J Yang, TF Yuan, L Zhao, K Wang, ...
Cell discovery 4 (1), 9, 2018
872018
Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding
Y Wu, G Qin, F Gao, Y Liu, CJ Vavricka, J Qi, H Jiang, K Yu, GF Gao
Scientific reports 3 (1), 1551, 2013
712013
Revealing Missing Human Protein Isoforms Based on Ab Initio Prediction, RNA-seq and Proteomics
Z Hu, HS Scott, G Qin, G Zheng, X Chu, L Xie, DL Adelson, BE Oftedal, ...
Scientific reports 5 (1), 10940, 2015
522015
Discovering novel quercetin-3-O-amino acid-esters as a new class of Src tyrosine kinase inhibitors
H Huang, Q Jia, J Ma, G Qin, Y Chen, Y Xi, L Lin, W Zhu, J Ding, H Jiang, ...
European journal of medicinal chemistry 44 (5), 1982-1988, 2009
492009
Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science
DR Unni, SAT Moxon, M Bada, M Brush, R Bruskiewich, JH Caufield, ...
Clinical and translational science 15 (8), 1848-1855, 2022
432022
Biomolecular network-based synergistic drug combination discovery
X Li, G Qin, Q Yang, L Chen, L Xie
BioMed research international 2016, 2016
432016
Long route or shortcut? A molecular dynamics study of traffic of thiocholine within the active-site gorge of acetylcholinesterase
Y Xu, JP Colletier, M Weik, G Qin, H Jiang, I Silman, JL Sussman
Biophysical journal 99 (12), 4003-4011, 2010
372010
Targeting the small-and intermediate-conductance Ca2+-activated potassium channels: The drug-binding pocket at the channel/calmodulin interface
M Cui, G Qin, K Yu, MS Bowers, M Zhang
Neurosignals 22 (2), 65-78, 2015
302015
Conformational transition and energy landscape of ErbB4 activated by neuregulin1β: one microsecond molecular dynamics simulations
Y Du, H Yang, Y Xu, X Cang, C Luo, Y Mao, Y Wang, G Qin, X Luo, ...
Journal of the American Chemical Society 134 (15), 6720-6731, 2012
282012
Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus (A/H1N1)?
K Yu, C Luo, G Qin, Z Xu, N Li, H Liu, X Shen, J Ma, Q Wang, C Yang, ...
Cell research 19 (10), 1221-1224, 2009
232009
Coordinated silencing of the Sp1-mediated long noncoding RNA MEG3 by EZH2 and HDAC3 as a prognostic factor in pancreatic ductal adenocarcinoma
T Han, M Zhuo, C Yuan, X Xiao, J Cui, G Qin, L Wang, F Jiao
Cancer biology & medicine 17 (4), 953, 2020
222020
How does influenza virus a escape from amantadine?
G Qin, K Yu, T Shi, C Luo, G Li, W Zhu, H Jiang
The Journal of Physical Chemistry B 114 (25), 8487-8493, 2010
202010
Progress toward a universal biomedical data translator
K Fecho, AT Thessen, SE Baranzini, C Bizon, JJ Hadlock, S Huang, ...
Clinical and Translational Science, 2022
182022
Exploring the RING-catalyzed ubiquitin transfer mechanism by MD and QM/MM calculations
Y Zhen, G Qin, C Luo, H Jiang, K Yu, G Chen
PloS one 9 (7), e101663, 2014
152014
The structural characterization of tumor fusion genes and proteins
D Wang, D Li, G Qin, W Zhang, J Ouyang, M Zhang, L Xie
Computational and Mathematical Methods in Medicine 2015, 2015
142015
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Articles 1–20