| Regulation of G2/M transition by inhibition of WEE1 and PKMYT1 kinases M Schmidt, A Rohe, C Platzer, A Najjar, F Erdmann, W Sippl Molecules 22 (12), 2045, 2017 | 166 | 2017 |
| Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis T Heimburg, A Chakrabarti, J Lancelot, M Marek, J Melesina, AT Hauser, ... Journal of Medicinal Chemistry 59 (6), 2423-2435, 2016 | 132 | 2016 |
| New 1, 3-dioxolane and 1, 3-dioxane derivatives as effective modulators to overcome multidrug resistance M Schmidt, J Ungvári, J Glöde, B Dobner, A Langner Bioorganic & medicinal chemistry 15 (6), 2283-2297, 2007 | 78 | 2007 |
| Structure-based design and biological characterization of selective histone deacetylase 8 (HDAC8) inhibitors with anti-neuroblastoma activity T Heimburg, FR Kolbinger, P Zeyen, E Ghazy, D Herp, K Schmidtkunz, ... Journal of Medicinal Chemistry 60 (24), 10188-10204, 2017 | 75 | 2017 |
| Application of docking and QM/MM-GBSA rescoring to screen for novel Myt1 kinase inhibitors K Wichapong, A Rohe, C Platzer, I Slynko, F Erdmann, M Schmidt, ... Journal of Chemical Information and Modeling 54 (3), 881-893, 2014 | 73 | 2014 |
| Synthesis and biochemical characterization of new phenothiazines and related drugs as MDR reversal agents M Schmidt, M Teitge, ME Castillo, T Brandt, B Dobner, A Langner Archiv der Pharmazie 341 (10), 624-638, 2008 | 33 | 2008 |
| Synthesis, molecular docking and biological characterization of pyrazine linked 2-aminobenzamides as new class I selective histone deacetylase (HDAC) inhibitors with anti … HS Ibrahim, M Abdelsalam, Y Zeyn, M Zessin, AHM Mustafa, MA Fischer, ... International Journal of Molecular Sciences 23 (1), 369, 2021 | 31 | 2021 |
| Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis T Bayer, A Chakrabarti, J Lancelot, TB Shaik, K Hausmann, J Melesina, ... ChemMedChem 13 (15), 1517-1529, 2018 | 26 | 2018 |
| Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1 E Ghazy, P Zeyen, D Herp, M Hügle, K Schmidtkunz, F Erdmann, ... European journal of medicinal chemistry 200, 112338, 2020 | 23 | 2020 |
| In vitro and in silico studies on substrate recognition and acceptance of human PKMYT1, a Cdk1 inhibitory kinase A Rohe, F Erdmann, C Bäßler, K Wichapong, W Sippl, M Schmidt Bioorganic & medicinal chemistry letters 22 (2), 1219-1223, 2012 | 23 | 2012 |
| A Fluorescence Anisotropy–Based Myt1 Kinase Binding Assay A Rohe, C Henze, F Erdmann, W Sippl, M Schmidt Assay and drug development technologies 12 (2), 136-144, 2014 | 21 | 2014 |
| Design, synthesis and biological characterization of histone deacetylase 8 (HDAC8) proteolysis targeting chimeras (PROTACs) with anti-neuroblastoma activity S Darwish, E Ghazy, T Heimburg, D Herp, P Zeyen, R Salem-Altintas, ... International journal of molecular sciences 23 (14), 7535, 2022 | 18 | 2022 |
| Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells P Zeyen, Y Zeyn, D Herp, F Mahmoudi, TZ Yesiloglu, F Erdmann, ... European Journal of Medicinal Chemistry, 114272, 2022 | 18 | 2022 |
| Computer-aided design, synthesis and biological characterization of novel inhibitors for PKMYT1 A Najjar, C Platzer, A Luft, CA Aßmann, NH Elghazawy, F Erdmann, ... European Journal of Medicinal Chemistry 161, 479-492, 2019 | 18 | 2019 |
| Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum B Sauer, TS Skinner-Adams, A Bouchut, MJ Chua, C Pierrot, F Erdmann, ... European Journal of Medicinal Chemistry 127, 22-40, 2017 | 16 | 2017 |
| First total synthesis of 1, 2-dipalmitoyl-3-(N-palmitoyl-6′-amino-6′-deoxy-α-d-glucosyl)-sn-glycerol—A glycoglycerolipid of a marine alga with a high inhibitor activity … C Göllner, C Philipp, B Dobner, W Sippl, M Schmidt Carbohydrate research 344 (13), 1628-1631, 2009 | 15 | 2009 |
| New modified single chained glycolipids. Part 1: synthesis of deoxy and partially O-methylated glycolipids with or without a sulfur containing spacer M Schmidt, SK Chatterjee, B Dobner, P Nuhn Chemistry and physics of lipids 114 (2), 139-147, 2002 | 15 | 2002 |
| Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II C Platzer, A Najjar, A Rohe, F Erdmann, W Sippl, M Schmidt Bioorganic & medicinal chemistry 26 (14), 4014-4024, 2018 | 14 | 2018 |
| Evaluation of potential Myt1 kinase inhibitors by TR-FRET based binding assay A Rohe, C Göllner, K Wichapong, F Erdmann, GMA Al-Mazaideh, W Sippl, ... European journal of medicinal chemistry 61, 41-48, 2013 | 14 | 2013 |
| Binding Free Energy (BFE) calculations and Quantitative Structure–Activity Relationship (QSAR) analysis of Schistosoma mansoni histone deacetylase 8 (sm HDAC8) inhibitors CV Simoben, E Ghazy, P Zeyen, S Darwish, M Schmidt, C Romier, ... Molecules 26 (9), 2584, 2021 | 13 | 2021 |
