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Patrick M. McLendon
Patrick M. McLendon
Verified email at cchmc.org
Title
Cited by
Cited by
Year
Enhanced autophagy ameliorates cardiac proteinopathy
MS Bhuiyan, JS Pattison, H Osinska, J James, J Gulick, PM McLendon, ...
The Journal of clinical investigation 123 (12), 5284-5297, 2013
3022013
Desmin-related cardiomyopathy: an unfolding story
PM McLendon, J Robbins
American Journal of Physiology-Heart and Circulatory Physiology 301 (4 …, 2011
1542011
Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy
PM McLendon, BS Ferguson, H Osinska, MS Bhuiyan, J James, ...
Proceedings of the National Academy of Sciences 111 (48), E5178-E5186, 2014
1182014
Poly (glycoamidoamine) vehicles promote pDNA uptake through multiple routes and efficient gene expression via caveolae-mediated endocytosis
PM McLendon, KM Fichter, TM Reineke
Molecular pharmaceutics 7 (3), 738-750, 2010
1102010
Polymer beacons for luminescence and magnetic resonance imaging of DNA delivery
JM Bryson, KM Fichter, WJ Chu, JH Lee, J Li, LA Madsen, PM McLendon, ...
Proceedings of the National Academy of Sciences 106 (40), 16913-16918, 2009
1082009
Proteotoxicity and cardiac dysfunction
PM McLendon, J Robbins
Circulation research 116 (11), 1863-1882, 2015
962015
Polymeric nucleic acid vehicles exploit active interorganelle trafficking mechanisms
KM Fichter, NP Ingle, PM McLendon, TM Reineke
ACS nano 7 (1), 347-364, 2013
942013
UBC9-mediated sumoylation favorably impacts cardiac function in compromised hearts
MK Gupta, PM McLendon, J Gulick, J James, K Khalili, J Robbins
Circulation research 118 (12), 1894-1905, 2016
692016
Carbohydrate polymers for nonviral nucleic acid delivery
A Sizovs, PM McLendon, S Srinivasachari, TM Reineke
Nucleic Acid Transfection, 131-190, 2010
672010
Toward targeting RNA structure: Branched peptides as cell-permeable ligands to TAR RNA
DI Bryson, W Zhang, PM McLendon, TM Reineke, WL Santos
ACS Chemical Biology 7 (1), 210-217, 2012
572012
Interaction of poly (glycoamidoamine) DNA delivery vehicles with cell-surface glycosaminoglycans leads to polyplex internalization in a manner not solely dependent on charge
PM McLendon, DJ Buckwalter, EM Davis, TM Reineke
Molecular pharmaceutics 7 (5), 1757-1768, 2010
402010
Ube2v1 positively regulates protein aggregation by modulating ubiquitin proteasome system performance partially through K63 ubiquitination
N Xu, J Gulick, H Osinska, Y Yu, PM McLendon, K Shay-Winkler, ...
Circulation research 126 (7), 907-922, 2020
242020
In vivo definition of cardiac myosin-binding protein C’s critical interactions with myosin
MS Bhuiyan, P McLendon, J James, H Osinska, J Gulick, B Bhandary, ...
Pflügers Archiv-European Journal of Physiology 468 (10), 1685-1695, 2016
232016
An unbiased high-throughput screen to identify novel effectors that impact on cardiomyocyte aggregate levels
PM McLendon, G Davis, J Gulick, SR Singh, N Xu, N Salomonis, ...
Circulation research 121 (6), 604-616, 2017
162017
A Polycation Scaffold Presenting Tunable “Click” Sites: Conjugation to Carbohydrate Ligands and Examination of Hepatocyte‐Targeted pDNA Delivery
CC Lee, G Grandinetti, PM McLendon, TM Reineke
Macromolecular Bioscience 10 (6), 585-598, 2010
162010
A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway
SR Singh, M Meyer-Jens, E Alizoti, WC Bacon, G Davis, H Osinska, ...
Autophagy 17 (10), 3124-3139, 2021
152021
Voluntary exercise and Atg7 overexpression induced autophagy ameliorates cardiac proteinopathy
MS Bhuiyan, JS Pattison, H Osinska, J James, J Gulick, PM McLendon, ...
Circulation 128 (suppl_22), A11097-A11097, 2013
52013
JAK1 Inhibitors reduce CRYABR120G aggregates in rat and human cardiomyocytes
E Alizoti, L Michler, E Orthey, H Osinska, J Gulick, B Klampe, T Schulze, ...
Journal of Molecular and Cellular Cardiology 173, S95-S96, 2022
12022
Ube2v1 Promotes Mutant αB-crystallin-induced Protein Aggregation
N Xu, P McLendon, J Gulick, H Osinska, J Robbins
Circulation Research 123 (Suppl_1), A238-A238, 2018
2018
Screening modulators of the ubiquitin-proteasome system and the autophagy-lysosomal pathway-Towards novel targets to treat proteotoxicity
SR Singh, WC Bacon, G Davis, J Gulick, H Osinska, P McLendon, ...
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 109, 23-23, 2017
2017
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Articles 1–20