| Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease PS Bernstein, B Li, PP Vachali, A Gorusupudi, R Shyam, BS Henriksen, ... Progress in retinal and eye research 50, 34-66, 2016 | 534 | 2016 |
| Processing of optineurin in neuronal cells X Shen, H Ying, Y Qiu, JS Park, R Shyam, ZL Chi, T Iwata, BYJT Yue Journal of biological chemistry 286 (5), 3618-3629, 2011 | 97 | 2011 |
| RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye R Shyam, A Gorusupudi, K Nelson, MP Horvath, PS Bernstein Proceedings of the National Academy of Sciences 114 (41), 10882-10887, 2017 | 92 | 2017 |
| Impairment of protein trafficking upon overexpression and mutation of optineurin BC Park, H Ying, X Shen, JS Park, Y Qiu, R Shyam, BYJT Yue PloS one 5 (7), e11547, 2010 | 75 | 2010 |
| All three human scavenger receptor class B proteins can bind and transport all three macular xanthophyll carotenoids R Shyam, P Vachali, A Gorusupudi, K Nelson, PS Bernstein Archives of biochemistry and biophysics 634, 21-28, 2017 | 52 | 2017 |
| Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth T Koga, X Shen, JS Park, Y Qiu, BC Park, R Shyam, BYJT Yue The American journal of pathology 176 (1), 343-352, 2010 | 40 | 2010 |
| Ammonia sensitive SLC4A11 mitochondrial uncoupling reduces glutamine induced oxidative stress DG Ogando, M Choi, R Shyam, S Li, JA Bonanno Redox biology 26, 101260, 2019 | 37 | 2019 |
| Cellular processing of myocilin Y Qiu, X Shen, R Shyam, BYJT Yue, H Ying PLoS One 9 (4), e92845, 2014 | 29 | 2014 |
| Effects of mutations and deletions in the human optineurin gene S Turturro, X Shen, R Shyam, BYJT Yue, H Ying Springerplus 3, 1-16, 2014 | 27 | 2014 |
| Developmentally regulated production of meso-zeaxanthin in chicken retinal pigment epithelium/choroid and retina A Gorusupudi, R Shyam, B Li, P Vachali, YK Subhani, K Nelson, ... Investigative ophthalmology & visual science 57 (4), 1853-1861, 2016 | 25 | 2016 |
| Mitochondrial ROS induced lysosomal dysfunction and autophagy impairment in an animal model of congenital hereditary endothelial dystrophy R Shyam, DG Ogando, M Choi, PB Liton, JA Bonanno Investigative Ophthalmology & Visual Science 62 (12), 15-15, 2021 | 20 | 2021 |
| Wnt gene expression in human trabecular meshwork cells R Shyam, X Shen, BYJT Yue, KK Wentz-Hunter Molecular Vision 16, 122, 2010 | 18 | 2010 |
| The H+ Transporter SLC4A11: Roles in Metabolism, Oxidative Stress and Mitochondrial Uncoupling JA Bonanno, R Shyam, M Choi, DG Ogando Cells 11 (2), 197, 2022 | 12 | 2022 |
| Inducible Slc4a11 knockout triggers corneal edema through perturbation of corneal endothelial pump DG Ogando, R Shyam, ET Kim, YC Wang, CY Liu, JA Bonanno Investigative Ophthalmology & Visual Science 62 (7), 28-28, 2021 | 9 | 2021 |
| Bicarbonate activates glycolysis and lactate production in corneal endothelial cells by increased pHi S Li, R Shyam, DG Ogando, JA Bonanno Experimental eye research 199, 108193, 2020 | 8 | 2020 |
| Mitochondrial ROS in Slc4a11 KO corneal endothelial cells lead to ER stress R Shyam, DG Ogando, JA Bonanno Frontiers in Cell and Developmental Biology 10, 878395, 2022 | 6 | 2022 |
| Autophagy in the eye: from physiology to pathophysiology PB Liton, K Boesze-Battaglia, ME Boulton, P Boya, TA Ferguson, ... Autophagy Reports 2 (1), 2178996, 2023 | 3 | 2023 |
| Rescue of the Congenital Hereditary Endothelial Dystrophy Mouse Model by Adeno-Associated Virus–Mediated Slc4a11 Replacement R Shyam, DG Ogando, ET Kim, S Murugan, M Choi, JA Bonanno Ophthalmology science 2 (1), 100084, 2022 | 2 | 2022 |
| Characterization of a novel mouse model for Fuchs Endothelial Corneal Dystrophy S Murugan, VS de Campos, SA Ghag, M Ng, R Shyam Investigative Ophthalmology & Visual Science 65 (4), 18-18, 2024 | | 2024 |
| OPEN ACCESS EDITED AND REVIEWED BY A Cuenda, R Shyam, D Vasudevan, R Shyam, DY Shu, ... Molecular mechanisms in ocular development and disease, 4, 2023 | | 2023 |
