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Xiaozheng (Mark) Xu
Xiaozheng (Mark) Xu
Sanofi Institute for Biomedical Research
Verified email at sanofi.com
Title
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Cited by
Year
Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
X Chen, W He, L Hu, J Li, Y Fang, X Wang, X Xu, Z Wang, K Huang, J Han
Cell research 26 (9), 1007-1020, 2016
6762016
PD-L1: CD80 cis-heterodimer triggers the co-stimulatory receptor CD28 while repressing the inhibitory PD-1 and CTLA-4 pathways
Y Zhao, CK Lee, CH Lin, RB Gassen, X Xu, Z Huang, C Xiao, C Bonorino, ...
Immunity 51 (6), 1059-1073. e9, 2019
2802019
Metformin induces human esophageal carcinoma cell pyroptosis by targeting the miR-497/PELP1 axis
L Wang, K Li, X Lin, Z Yao, S Wang, X Xiong, Z Ning, J Wang, X Xu, ...
Cancer letters 450, 22-31, 2019
1812019
Mechanistic insights revealed by the crystal structure of a histidine kinase with signal transducer and sensor domains
C Wang, J Sang, J Wang, M Su, JS Downey, Q Wu, S Wang, Y Cai, X Xu, ...
PLoS biology 11 (2), e1001493, 2013
1772013
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses
KL Banta, X Xu, AS Chitre, A Au-Yeung, C Takahashi, WE O’Gorman, ...
Immunity 55 (3), 512-526. e9, 2022
1602022
Group-DIA: analyzing multiple data-independent acquisition mass spectrometry data files
Y Li, CQ Zhong, X Xu, S Cai, X Wu, Y Zhang, J Chen, J Shi, S Lin, J Han
Nature methods 12 (12), 1105-1106, 2015
1082015
PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2
X Xu, B Hou, A Fulzele, T Masubuchi, Y Zhao, Z Wu, Y Hu, Y Jiang, Y Ma, ...
Journal of Cell Biology 219 (6), e201905085, 2020
902020
RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes
X Li, CQ Zhong, R Wu, X Xu, ZH Yang, S Cai, X Wu, X Chen, Z Yin, Q He, ...
Protein & Cell 12 (11), 858-876, 2021
842021
Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics
X Wu, L Tian, J Li, Y Zhang, V Han, Y Li, X Xu, H Li, X Chen, J Chen, ...
Molecular & Cellular Proteomics 11 (12), 1640-1651, 2012
802012
Gene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses
Z Zhang, X Xu, J Ma, J Wu, Y Wang, R Zhou, J Han
The Journal of Immunology 190 (7), 3517-3524, 2013
412013
Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors
X Xu, T Masubuchi, Q Cai, Y Zhao, E Hui
Elife 10, e74276, 2021
292021
Quantitative phosphoproteomic analysis of RIP3‐dependent protein phosphorylation in the course of TNF‐induced necroptosis
CQ Zhong, Y Li, D Yang, N Zhang, X Xu, Y Wu, J Chen, J Han
Proteomics 14 (6), 713-724, 2014
292014
Chimeric RNA ASTN2-PAPPAas aggravates tumor progression and metastasis in human esophageal cancer
L Wang, X Xiong, Z Yao, J Zhu, Y Lin, W Lin, K Li, X Xu, Y Guo, Y Chen, ...
Cancer letters 501, 1-11, 2021
212021
cis-B7: CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
Y Zhao, C Caron, YY Chan, CK Lee, X Xu, J Zhang, T Masubuchi, C Wu, ...
Immunity 56 (6), 1187-1203. e12, 2023
202023
CTLA4 depletes T cell endogenous and trogocytosed B7 ligands via cis-endocytosis
X Xu, P Dennett, J Zhang, A Sherrard, Y Zhao, T Masubuchi, JD Bui, ...
Journal of Experimental Medicine 220 (7), e20221391, 2023
112023
BTLA and PD-1 employ distinct phosphatases to differentially repress T cell signaling
X Xu, A Fulzele, Y Zhao, Z Wu, Y Hu, Y Jiang, Y Ma, H Wang, G Fu, ...
BioRxiv, 669812, 2019
72019
Molecular Features Underlying Shp1/Shp2 Discrimination by Immune Checkpoint Receptors
X Xu, T Masubuchi, Y Zhao, E Hui
bioRxiv, 2021.06. 23.449580, 2021
12021
Cis-B7:CD28 interactions at invaginated synaptic membranes activate CD28 and promote T cell function
Y Zhao, C Caron, YY Chan, CK Lee, X Xu, JD Bui, E Hui
Cancer Research 83 (7_Supplement), 606-606, 2023
2023
PD-L1: CD80 Heterodimer Triggers CD28 While Repressing Both PD-1 and CTLA4 Pathways
Y Zhao, CH Lin, C Lee, X Xu, Z Huang, C Xiao, J Bui, LF Lu, E Hui
bioRxiv, 615138, 2019
2019
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