Which GABAA-receptor subtypes really occur in the brain? RM McKernan, PJ Whiting Trends in neurosciences 19 (4), 139-143, 1996 | 1546 | 1996 |
Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor α1 subtype RM McKernan, TW Rosahl, DS Reynolds, C Sur, KA Wafford, JR Atack, ... Nature neuroscience 3 (6), 587-592, 2000 | 1175 | 2000 |
Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the α5 subunit of the GABAAReceptor N Collinson, FM Kuenzi, W Jarolimek, KA Maubach, R Cothliff, C Sur, ... Journal of Neuroscience 22 (13), 5572-5580, 2002 | 767 | 2002 |
DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling JK Millar, BS Pickard, S Mackie, R James, S Christie, SR Buchanan, ... Science 310 (5751), 1187-1191, 2005 | 756 | 2005 |
Pharmacological characterization of a novel cell line expressing human α4β3δ GABAA receptors N Brown, J Kerby, TP Bonnert, PJ Whiting, KA Wafford British journal of pharmacology 136 (7), 965-974, 2002 | 698 | 2002 |
Phase 1 clinical study of an embryonic stem cell–derived retinal pigment epithelium patch in age-related macular degeneration L da Cruz, K Fynes, O Georgiadis, J Kerby, YH Luo, A Ahmado, A Vernon, ... Nature biotechnology 36 (4), 328-337, 2018 | 638 | 2018 |
Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors SM Chambers, Y Qi, Y Mica, G Lee, XJ Zhang, L Niu, J Bilsland, L Cao, ... Nature biotechnology 30 (7), 715-720, 2012 | 610 | 2012 |
Brain α-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily R Schoepfer, WG Conroy, P Whiting, M Gore, J Lindstrom Neuron 5 (1), 35-48, 1990 | 574 | 1990 |
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia LM Camargo, V Collura, JC Rain, K Mizuguchi, H Hermjakob, S Kerrien, ... Molecular psychiatry 12 (1), 74-86, 2007 | 521 | 2007 |
Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site. P Whiting, RM McKernan, LL Iversen Proceedings of the National Academy of Sciences 87 (24), 9966-9970, 1990 | 508 | 1990 |
Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover. X Peng, V Gerzanich, R Anand, PJ Whiting, J Lindstrom Molecular pharmacology 46 (3), 523-530, 1994 | 492 | 1994 |
The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid D Belelli, JJ Lambert, JA Peters, K Wafford, PJ Whiting Proceedings of the National Academy of Sciences 94 (20), 11031-11036, 1997 | 484 | 1997 |
Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure R Anand, WG Conroy, R Schoepfer, P Whiting, J Lindstrom Journal of Biological Chemistry 266 (17), 11192-11198, 1991 | 456 | 1991 |
Molecular and functional diversity of the expanding GABA‐A receptor gene family PJ Whiting, TP Bonnert, RM McKernan, S Farrar, BL Bourdelles, ... Annals of the New York Academy of Sciences 868 (1), 645-653, 1999 | 427 | 1999 |
Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system LW Swanson, DM Simmons, PJ Whiting, J Lindstrom Journal of Neuroscience 7 (10), 3334-3342, 1987 | 424 | 1987 |
GABA-A receptor subtypes in the brain: a paradigm for CNS drug discovery? PJ Whiting Drug discovery today 8 (10), 445-450, 2003 | 395 | 2003 |
θ, a novel γ-aminobutyric acid type A receptor subunit TP Bonnert, RM McKernan, S Farrar, B le Bourdellès, RP Heavens, ... Proceedings of the National Academy of Sciences 96 (17), 9891-9896, 1999 | 392 | 1999 |
Purification and characterization of a nicotinic acetylcholine receptor from rat brain. P Whiting, J Lindstrom Proceedings of the National Academy of Sciences 84 (2), 595-599, 1987 | 376 | 1987 |
Stoichiometry of a ligand-gated ion channel determined by fluorescence energy transfer SJ Farrar, PJ Whiting, TP Bonnert, RM McKernan Journal of Biological Chemistry 274 (15), 10100-10104, 1999 | 326 | 1999 |
Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse … T Priestley, P Laughton, J Myers, B Le Bourdelles, J Kerby, PJ Whiting Molecular pharmacology 48 (5), 841-848, 1995 | 324 | 1995 |