| Design of an in vitro biocatalytic cascade for the manufacture of islatravir MA Huffman, A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, ... Science 366 (6470), 1255-1259, 2019 | 438 | 2019 |
| A practical, one-pot synthesis of sulfonylated pyridines KM Maloney, JT Kuethe, K Linn Organic Letters 13 (1), 102-105, 2011 | 145 | 2011 |
| Engineered ribosyl-1-kinase enables concise synthesis of molnupiravir, an antiviral for COVID-19 JA McIntosh, T Benkovics, SM Silverman, MA Huffman, J Kong, ... ACS Central Science 7 (12), 1980-1985, 2021 | 101 | 2021 |
| A General Procedure for the Preparation of β-Ketophosphonates KM Maloney, JYL Chung The Journal of Organic Chemistry 74 (19), 7574-7576, 2009 | 85 | 2009 |
| Synthesis of complex phenols enabled by a rationally designed hydroxide surrogate PS Fier, KM Maloney Angewandte Chemie 129 (16), 4549-4553, 2017 | 80 | 2017 |
| NHC-Catalyzed deamination of primary sulfonamides: a platform for late-stage functionalization PS Fier, KM Maloney Journal of the American Chemical Society 141 (4), 1441-1445, 2019 | 65 | 2019 |
| Reagent design and ligand evolution for the development of a mild copper-catalyzed hydroxylation reaction PS Fier, KM Maloney Organic letters 19 (11), 3033-3036, 2017 | 64 | 2017 |
| Asymmetric Synthesis of cis-2,5-Disubstituted Pyrrolidine, the Core Scaffold of β3-AR Agonists F Xu, JYL Chung, JC Moore, Z Liu, N Yoshikawa, RS Hoerrner, J Lee, ... Organic letters 15 (6), 1342-1345, 2013 | 57 | 2013 |
| Total synthesis of quinolizidine alkaloid (−)-217A. Application of iminoacetonitrile cycloadditions in organic synthesis KM Maloney, RL Danheiser Organic letters 7 (14), 3115-3118, 2005 | 55 | 2005 |
| Direct conversion of haloarenes to phenols under mild, transition-metal-free conditions PS Fier, KM Maloney Organic letters 18 (9), 2244-2247, 2016 | 53 | 2016 |
| The application of modern reactions in large-scale synthesis K Lovato, PS Fier, KM Maloney Nature Reviews Chemistry 5 (8), 546-563, 2021 | 49 | 2021 |
| One-pot iodination of hydroxypyridines KM Maloney, E Nwakpuda, JT Kuethe, J Yin The Journal of Organic Chemistry 74 (14), 5111-5114, 2009 | 45 | 2009 |
| Copper-catalyzed deoxygenative C2-sulfonylation of quinoline N-oxides with DABSO and phenyldiazonium tetrafluoroborates for the synthesis of 2-sulfonylquinolines via a radical … GH Li, DQ Dong, Q Deng, SQ Yan, ZL Wang Synthesis 51 (17), 3313-3319, 2019 | 44 | 2019 |
| Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis J Liu, D Guiadeen, A Krikorian, X Gao, J Wang, SB Boga, AB Alhassan, ... ACS Medicinal Chemistry Letters 7 (2), 198-203, 2016 | 44 | 2016 |
| Reductive cleavage of secondary sulfonamides: converting terminal functional groups into versatile synthetic handles PS Fier, S Kim, KM Maloney Journal of the American Chemical Society 141 (46), 18416-18420, 2019 | 39 | 2019 |
| Kilo-Scale Electrochemical Oxidation of a Thioether to a Sulfone: A Workflow for Scaling up Electrosynthesis C Bottecchia, D Lehnherr, F Lévesque, M Reibarkh, Y Ji, VL Rodrigues, ... Organic Process Research & Development 26 (8), 2423-2437, 2022 | 28 | 2022 |
| Development of a green and sustainable manufacturing process for gefapixant citrate (MK-7264) part 1: introduction and process overview H Ren, KM Maloney, K Basu, MJ Di Maso, GR Humphrey, F Peng, ... Organic Process Research & Development 24 (11), 2445-2452, 2020 | 28 | 2020 |
| Potassium isopropyl xanthate (PIX): an ultra-efficient palladium scavenger H Ren, CA Strulson, G Humphrey, R Xiang, G Li, DR Gauthier, ... Green chemistry 19 (17), 4002-4006, 2017 | 27 | 2017 |
| A concise synthesis of 3, 4-fused spiro [isobenzofuran-3-ones], spiro [furo [3, 4-b] pyridin-5 (7H)-ones], 3-aryl-, and alkylphthalides JT Kuethe, KM Maloney Tetrahedron 69 (25), 5248-5258, 2013 | 24 | 2013 |
| Synthesis of islatravir enabled by a catalytic, enantioselective alkynylation of a ketone NR Patel, CC Nawrat, M McLaughlin, Y Xu, MA Huffman, H Yang, H Li, ... Organic Letters 22 (12), 4659-4664, 2020 | 23 | 2020 |
