BRCA1–BARD1 promotes RAD51-mediated homologous DNA pairing W Zhao, JB Steinfeld, F Liang, X Chen, DG Maranon, C Jian Ma, Y Kwon, ... Nature 550 (7676), 360-365, 2017 | 340 | 2017 |
Promotion of BRCA2-dependent homologous recombination by DSS1 via RPA targeting and DNA mimicry W Zhao, S Vaithiyalingam, J San Filippo, DG Maranon, J Jimenez-Sainz, ... Molecular cell 59 (2), 176-187, 2015 | 184 | 2015 |
Enhancement of BLM-DNA2-mediated long-range DNA end resection by CtIP JM Daley, J Jimenez-Sainz, W Wang, AS Miller, X Xue, KA Nguyen, ... Cell reports 21 (2), 324-332, 2017 | 88 | 2017 |
PINK1 displays tissue-specific subcellular location and regulates apoptosis and cell growth in breast cancer cells A Berthier, S Navarro, J Jiménez-Sáinz, I Roglá, F Ripoll, J Cervera, ... Human pathology 42 (1), 75-87, 2011 | 79 | 2011 |
Distinct binding of BRCA2 BRC repeats to RAD51 generates differential DNA damage sensitivity G Chatterjee, J Jimenez-Sainz, T Presti, T Nguyen, RB Jensen Nucleic Acids Research 44 (11), 5256-5270, 2016 | 67 | 2016 |
Imprecise medicine: BRCA2 variants of uncertain significance (VUS), the challenges and benefits to integrate a functional assay workflow with clinical decision rules J Jimenez-Sainz, RB Jensen Genes 12 (5), 780, 2021 | 17 | 2021 |
PINK1 regulates histone H3 trimethylation and gene expression by interaction with the polycomb protein EED/WAIT1 A Berthier, J Jiménez-Sáinz, R Pulido Proceedings of the National Academy of Sciences 110 (36), 14729-14734, 2013 | 14 | 2013 |
The post-synaptic function of Brca2 CX Wang, J Jimenez-Sainz, RB Jensen, AV Mazin Scientific reports 9 (1), 4554, 2019 | 12 | 2019 |
DNA fiber combing protocol using in-house reagents and coverslips to analyze replication fork dynamics in mammalian cells G Moore, JJ Sainz, RB Jensen STAR protocols 3 (2), 101371, 2022 | 8 | 2022 |
Promotion of RAD51-mediated homologous DNA pairing by BRCA1-BARD1 W Zhao, JB Steinfeld, F Liang, X Chen, DG Maranon, CJ Ma, Y Kwon, ... Nature 550 (7676), 360, 2017 | 8 | 2017 |
BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair J Jimenez-Sainz, J Mathew, G Moore, S Lahiri, J Garbarino, JP Eder, ... Elife 11, e79183, 2022 | 5 | 2022 |
The pathogenic R3052W BRCA2 variant disrupts homology-directed repair by failing to localize to the nucleus J Jimenez-Sainz, A Krysztofiak, J Garbarino, F Rogers, RB Jensen Frontiers in Genetics 13, 884210, 2022 | 4 | 2022 |
Protecting the code: DNA double-strand break repair pathway choice JK Singh, SM Noordermeer, J Jimenez-Sainz, DG Maranon, M Altmeyer Frontiers in Genetics 13, 993889, 2022 | 1 | 2022 |
PINK1: an anti-apoptotic and anti-proliferative protein in human breast cancer cells J Jiménez-Sainz, A Berthier, R Pulido FEBS JOURNAL 279, 320-320, 2012 | 1 | 2012 |
Cancer missense mutations in the BRC repeats of BRCA2 protein disrupt RAD51 binding and activity leading to chemotherapeutic sensitivity J Jimenez-Sainz, J Mathew, J Garbarino, JP Eder, RB Jensen bioRxiv, 2021.09. 24.461749, 2021 | | 2021 |
Abstract GMM-033: CONDITIONAL BRCA2 SWITCH IN HUMAN CELLS TO STUDY TUMOR PROGRESSION J Jimenez-Sainz, RB Jensen Clinical Cancer Research 25 (22_Supplement), GMM-033-GMM-033, 2019 | | 2019 |
CONDITIONAL BRCA2 SWITCH IN HUMAN CELLS TO STUDY TUMOR PROGRESSION J Jimenez-Sainz, RB Jensen CLINICAL CANCER RESEARCH 25 (22), 96-96, 2019 | | 2019 |
RAD51 has an anti-recombinase activity that is countered by BRCA2 - In vitro C Wang, J Jimenez-Sainz, RB Jensen, AA Mazin Cancer Research 79 (13_Supplement), 1748-1748, 2019 | | 2019 |
Focus: Drug Development: Applying Pharmacogenomics in Therapeutics J Jimenez-Sainz The Yale Journal of Biology and Medicine 90 (1), 158, 2017 | | 2017 |
PINK1: a critical protein kinase in the molecular mechanisms involved in Cancer and Parkinson's disease JJ Sainz Universitat de València, 2012 | | 2012 |