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Adam Cribbs
Adam Cribbs
Group leader in Computational Biology, University of Oxford
Verified email at imm.ox.ac.uk - Homepage
Title
Cited by
Cited by
Year
Treg cell function in rheumatoid arthritis is compromised by CTLA‐4 promoter methylation resulting in a failure to activate the indoleamine 2, 3‐dioxygenase pathway
AP Cribbs, A Kennedy, H Penn, JE Read, P Amjadi, P Green, K Syed, ...
Arthritis & rheumatology 66 (9), 2344-2354, 2014
1612014
Methotrexate restores regulatory T cell function through demethylation of the FoxP3 upstream enhancer in patients with rheumatoid arthritis
AP Cribbs, A Kennedy, H Penn, P Amjadi, P Green, JE Read, F Brennan, ...
Arthritis & rheumatology 67 (5), 1182-1192, 2015
1592015
Simplified production and concentration of lentiviral vectors to achieve high transduction in primary human T cells
AP Cribbs, A Kennedy, B Gregory, FM Brennan
BMC biotechnology 13, 1-8, 2013
1562013
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ...
Cell 185 (5), 916-938. e58, 2022
1522022
An essential role for the Zn2+ transporter ZIP7 in B cell development
C Anzilotti, DJ Swan, B Boisson, M Deobagkar-Lele, C Oliveira, ...
Nature immunology 20 (3), 350-361, 2019
1112019
Indoleamine 2, 3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development
JE Cole, N Astola, AP Cribbs, ME Goddard, I Park, P Green, AH Davies, ...
Proceedings of the National Academy of Sciences 112 (42), 13033-13038, 2015
952015
Focus: Genome editing: Science and bioethics of CRISPR-Cas9 gene editing: An analysis towards separating facts and fiction
AP Cribbs, SMW Perera
The Yale journal of biology and medicine 90 (4), 625, 2017
892017
Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells
A Cribbs, ES Hookway, G Wells, M Lindow, S Obad, H Oerum, RK Prinjha, ...
Journal of Biological Chemistry 293 (7), 2422-2437, 2018
822018
Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming
A Ebrahimi, K Sevinç, G Gürhan Sevinç, AP Cribbs, M Philpott, F Uyulur, ...
Nature chemical biology 15 (5), 519-528, 2019
812019
Resistance to regulatory T cell-mediated suppression in rheumatoid arthritis can be bypassed by ectopic foxp3 expression in pathogenic synovial T cells
PA Beavis, B Gregory, P Green, AP Cribbs, A Kennedy, P Amjadi, ...
Proceedings of the national academy of sciences 108 (40), 16717-16722, 2011
742011
Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism
AP Cribbs, S Terlecki-Zaniewicz, M Philpott, J Baardman, D Ahern, ...
Proceedings of the National Academy of Sciences 117 (11), 6056-6066, 2020
672020
A novel upstream enhancer of FOXP3, sensitive to methylation‐induced silencing, exhibits dysregulated methylation in rheumatoid arthritis Treg cells
A Kennedy, EM Schmidt, AP Cribbs, H Penn, P Amjadi, K Syed, JE Read, ...
European journal of immunology 44 (10), 2968-2978, 2014
632014
Hypoxia induces transcriptional and translational downregulation of the type I IFN pathway in multiple cancer cell types
A Miar, E Arnaiz, E Bridges, S Beedie, AP Cribbs, DJ Downes, ...
Cancer research 80 (23), 5245-5256, 2020
592020
Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study
M Guo, C Bafligil, T Tapmeier, C Hubbard, S Manek, C Shang, ...
BMC medicine 18, 1-16, 2020
582020
Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq
M Philpott, J Watson, A Thakurta, T Brown Jr, T Brown Sr, U Oppermann, ...
Nature biotechnology 39 (12), 1517-1520, 2021
562021
Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300
LM Williams, FE McCann, MA Cabrita, T Layton, A Cribbs, B Knezevic, ...
Proceedings of the National Academy of Sciences 117 (34), 20753-20763, 2020
532020
Towards an understanding of the role of DNA methylation in rheumatoid arthritis: therapeutic and diagnostic implications
A Cribbs, M Feldmann, U Oppermann
Therapeutic advances in musculoskeletal disease 7 (5), 206-219, 2015
492015
Interleukin-17A causes osteoarthritis-like transcriptional changes in human osteoarthritis-derived chondrocytes and synovial fibroblasts in vitro
JY Mimpen, MJ Baldwin, AP Cribbs, M Philpott, SG Dakin, SJB Snelling
Frontiers in immunology 12, 676173, 2021
342021
A chemical probe for tudor domain protein Spindlin1 to investigate chromatin function
V Fagan, C Johansson, C Gileadi, O Monteiro, JE Dunford, R Nibhani, ...
Journal of medicinal chemistry 62 (20), 9008-9025, 2019
342019
Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death
L Cottone, AP Cribbs, G Khandelwal, G Wells, L Ligammari, M Philpott, ...
Cancer Research 80 (20), 4540-4551, 2020
332020
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