Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM KA Iyer, Y Hu, AR Nayak, N Kurebayashi, T Murayama, M Samsó Science Advances 6 (31), eabb2964, 2020 | 54 | 2020 |
Multi-modal antidepressant-like action of 6- and 7-chloro-2-aminodihydroquinazolines in the mouse tail suspension test KA Iyer, K Alix, JM Eltit, E Solis Jr., X Pan, MD Argade, SN Khatri, ... Psychopharmacology, 1-12, 2019 | 12 | 2019 |
The Evolving Landscape of Antibody–Drug Conjugates: In Depth Analysis of Recent Research Progress JM Sasso, R Tenchov, R Bird, KA Iyer, K Ralhan, Y Rodriguez, QA Zhou Bioconjugate Chemistry 34 (11), 1951-2000, 2023 | 11 | 2023 |
Reevaluation of fenpropimorph as a σ receptor ligand: Structure-affinity relationship studies at human σ1 receptors E Sguazzini, HR Schmidt, KA Iyer, AC Kruse, M Dukat Bioorganic & Medicinal Chemistry Letters 27 (13), 2912-2919, 2017 | 9 | 2017 |
A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3) X Pan, KA Iyer, H Liu, DH Sweet, M Dukat Bioorganic & Medicinal Chemistry Letters 27 (18), 4440-4445, 2017 | 7 | 2017 |
Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM KA Iyer, Y Hu, T Klose, T Murayama, M Samsó Proceedings of the National Academy of Sciences 119 (30), e2122140119, 2022 | 6 | 2022 |
Three-dimensional perspective on ryanodine receptor mutations causing skeletal and cardiac muscle-related diseases KA Iyer, V Barnakov, M Samsó Current Opinion in Pharmacology 68, 102327, 2023 | 4 | 2023 |
Purification of Recombinant Wild Type and Mutant Ryanodine Receptors Expressed in HEK293 Cells Y Hu, KA Iyer, AR Nayak, N Kurebayashi, T Murayama, M Samsó Bio-protocol 11 (15), e4112-e4112, 2021 | 3 | 2021 |
Emerging Targets and Therapeutics in Immuno-Oncology Landscape: Insights from Natural Language Processing Analysis K Iyer, J Ivanov, R Tenchov, K Ralhan, Y Rodriguez, J Sasso, S Scott, ... | 1 | 2023 |
Emerging topics–bibliometric-based methodology J Ivanov, A Lipkus, H Chen, C Aultman, K Iyer, R Tenchov, Q Zhou | 1 | 2023 |
Structural characterization of MH/CCD NTD mutations in skeletal ryanodine receptor by cryo-EM KA Iyer, Y Hu, T Klose, T Murayama, M Samso Biophysical Journal 121 (3), 91a-92a, 2022 | 1 | 2022 |
Cryo-EM reveals local and global structural rearrangements in RYR mutants: Calcium Signaling and Excitation–Contraction in Cardiac, Skeletal and Smooth Muscle KA Iyer, Y Hu, T Klose, T Murayama, M Samsó Journal of General Physiology 154 (9), e2021ecc44, 2021 | 1 | 2021 |
Dihydroquinazolines: A novel class of hOCT3 inhibitors M Dukat, X Pan, M Argade, K Iyer, P Mosier, D Sweet ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015 | 1 | 2015 |
Trends in carbon nanotube research and development: A landscape view of emerging applications and materials K Hughes, K Iyer, R Bird, J Ivanov, S Banerjee, G Georges, Q Zhou | | 2024 |
Navigating Antibacterial Frontiers: Landscape Analysis of Antibiotics, Resistance Mechanisms and Emerging Therapeutic Strategies K Ralhan, K Iyer, LL Diaz, R Bird, Q Zhou | | 2024 |
A Perspective on Covalent Inhibitors: Research and Development Trends of Warheads and Targets H Chen, R Bird, DS Wang, LL Diaz, K Iyer, G Gustafson, J Kato-Weinstein, ... | | 2023 |
High-resolution cryo-EM structures of the magnesium-inhibited and calcium-inactivated RyR1 AR Nayak, W Rangubpit, AH Will, Y Hu, K Iyer, P Castro-Hartmann, ... Biophysical Journal 121 (3), 13a, 2022 | | 2022 |
Phosphorylation of cardiac ryanodine receptor (RyR2): a structure-function study of phosphomimetic and phospho-null triple mutants Y Hu, KA Iyer, AR Nayak, JM Eltit, N Kurebayashi, T Murayama, M Samso Biophysical Journal 121 (3), 379a, 2022 | | 2022 |
Cryo-Em Studies of Phosphomimetic and Phospho-Null Triple Mutants of Cardiac Ryanodine Receptor (RyR2) Y Hu, K Iyer, AR Nayak, T Klose, JM Eltit, N Kurebayashi, T Murayama, ... Biophysical Journal 120 (3), 239a, 2021 | | 2021 |
X-ray crystal structure of a 2-amino-3, 4-dihydroquinazoline 5-HT3 serotonin receptor antagonist and related analogs AS Abdelkhalek, FN Musayev, KA Iyer, P Hemanth, MK Safo, M Dukat Journal of Molecular Structure 1202, 127276, 2020 | | 2020 |