A comprehensive mathematical model for three-body binding equilibria EF Douglass Jr, CJ Miller, G Sparer, H Shapiro, DA Spiegel Journal of the American Chemical Society 135 (16), 6092-6099, 2013 | 345 | 2013 |
Identification of natural RORγ ligands that regulate the development of lymphoid cells FR Santori, P Huang, SA Van De Pavert, EF Douglass, DJ Leaver, ... Cell metabolism 21 (2), 286-298, 2015 | 219 | 2015 |
A “turn-on” fluorescent sensor for methylglyoxal T Wang, EF Douglass Jr, KJ Fitzgerald, DA Spiegel Journal of the American Chemical Society 135 (33), 12429-12433, 2013 | 176 | 2013 |
Quantitative assessment of protein activity in orphan tissues and single cells using the metaVIPER algorithm H Ding, EF Douglass Jr, AM Sonabend, A Mela, S Bose, C Gonzalez, ... Nature communications 9 (1), 1471, 2018 | 107 | 2018 |
Effect of electrode roughness on the capacitive behavior of self-assembled monolayers EF Douglass Jr, PF Driscoll, D Liu, NA Burnham, CR Lambert, ... Analytical chemistry 80 (20), 7670-7677, 2008 | 89 | 2008 |
A modular master regulator landscape controls cancer transcriptional identity EO Paull, A Aytes, SJ Jones, PS Subramaniam, FM Giorgi, EF Douglass, ... Cell 184 (2), 334-351. e20, 2021 | 80 | 2021 |
Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators CE Jakobsche, CG Parker, RN Tao, MD Kolesnikova, EF Douglass Jr, ... ACS chemical biology 8 (11), 2404-2411, 2013 | 68 | 2013 |
Chemically synthesized molecules with the targeting and effector functions of antibodies PJ McEnaney, KJ Fitzgerald, AX Zhang, EF Douglass Jr, W Shan, A Balog, ... Journal of the American Chemical Society 136 (52), 18034-18043, 2014 | 55 | 2014 |
A community challenge for a pancancer drug mechanism of action inference from perturbational profile data EF Douglass, RJ Allaway, B Szalai, W Wang, T Tian, A Fernández-Torras, ... Cell Reports Medicine 3 (1), 2022 | 39 | 2022 |
Illuminating HIV gp120-ligand recognition through computationally-driven optimization of antibody-recruiting molecules CG Parker, MK Dahlgren, RN Tao, DT Li, EF Douglass, T Shoda, ... Chemical science 5 (6), 2311-2317, 2014 | 26 | 2014 |
Photocurrent generation in noncovalently assembled multilayered thin films PF Driscoll, EF Douglass, M Phewluangdee, ER Soto, CGF Cooper, ... Langmuir 24 (9), 5140-5145, 2008 | 19 | 2008 |
The host cell virocheckpoint: identification and pharmacologic targeting of novel mechanistic determinants of coronavirus-mediated hijacked cell states P Laise, G Bosker, X Sun, Y Shen, EF Douglass, C Karan, RB Realubit, ... BioRxiv, 2020 | 15 | 2020 |
OncoLoop: A network-based precision cancer medicine framework A Vasciaveo, JM Arriaga, FN De Almeida, M Zou, EF Douglass Jr, ... Cancer discovery 13 (2), 386-409, 2023 | 12 | 2023 |
A Transcriptome-Based Precision Oncology Platform for Patient–Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies PS Mundi, FS Dela Cruz, A Grunn, D Diolaiti, A Mauguen, AR Rainey, ... Cancer discovery 13 (6), 1386-1407, 2023 | 6 | 2023 |
Targeting the T-cell lymphoma epigenome induces cell death, cancer testes antigens, immune-modulatory signaling pathways L Scotto, C Kinahan, E Douglass, C Deng, M Safari, B Casadei, E Marchi, ... Molecular cancer therapeutics 20 (8), 1422-1430, 2021 | 5 | 2021 |
A Modular Master Regulator Landscape Determines the Impact of Genetic Alterations on the Transcriptional Identity of Cancer Cells EO Paull, A Aytes, P Subramaniam, FM Giorgi, EF Douglass, B Chu, ... BioRxiv, 758268, 2019 | 4 | 2019 |
A comprehensive kinetic model for ternary complex catalysis EF Douglass Jr, CJ Miller | 2 | 2022 |
Bridging “Big Data” and Mechanistic Insight To Enable Precision Medicine EF Douglass Jr Chembiochem 21 (21), 3047-3050, 2020 | 2 | 2020 |
Comment on a suite of mathematical solutions to describe ternary complex formation and their application to targeted protein degradation by heterobifunctional ligands EF Douglass, DA Spiegel Journal of Biological Chemistry 296, 2021 | 1 | 2021 |
Development of a Novel Tool To Demystify Drug Distribution at Tissue‐Blood Barriers EA Hughes, R Zieliński, AE Ray, W Priebe, EF Douglass Junior ChemBioChem 24 (13), e202200804, 2023 | | 2023 |