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Francis J O'Reilly
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Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology
FJ O’Reilly, J Rappsilber
Nature structural & molecular biology 25 (11), 1000-1008, 2018
2952018
In-cell architecture of an actively transcribing-translating expressome
FJ O'Reilly, L Xue, A Graziadei, L Sinn, S Lenz, D Tegunov, C Blötz, ...
Science 369 (6503), 554-557, 2020
2132020
M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation
HP Morgan, FJ O’Reilly, MA Wear, JR O’Neill, LA Fothergill-Gilmore, ...
Proceedings of the National Academy of Sciences 110 (15), 5881-5886, 2013
1682013
Defining a minimal cell: essentiality of small ORF s and nc RNA s in a genome‐reduced bacterium
M Lluch‐Senar, J Delgado, WH Chen, V Lloréns‐Rico, FJ O'Reilly, ...
Molecular systems biology 11 (1), 780, 2015
1552015
An integrated workflow for crosslinking mass spectrometry
ML Mendes, L Fischer, ZA Chen, M Barbon, FJ O'Reilly, SH Giese, ...
Molecular systems biology 15 (9), e8994, 2019
1382019
First community-wide, comparative cross-linking mass spectrometry study
C Iacobucci, C Piotrowski, R Aebersold, BC Amaral, P Andrews, K Bernfur, ...
Analytical chemistry 91 (11), 6953-6961, 2019
1252019
A folded conformation of MukBEF and cohesin
F Bürmann, BG Lee, T Than, L Sinn, FJ O’Reilly, S Yatskevich, ...
Nature structural & molecular biology 26 (3), 227-236, 2019
1232019
A Structure-Based Mechanism for DNA Entry into the Cohesin Ring
TL Higashi, P Eickhoff, JS Simoes, J Locke, A Nans, HR Flynn, ...
Molecular Cell 79 (6), 917-933, 2020
1162020
Capturing protein communities by structural proteomics in a thermophilic eukaryote
PL Kastritis, FJ O'Reilly, T Bock, Y Li, MZ Rogon, K Buczak, N Romanov, ...
Molecular systems biology 13 (7), 936, 2017
1112017
The structure of human thyroglobulin
F Coscia, A Taler-Verčič, VT Chang, L Sinn, FJ O’Reilly, T Izoré, M Renko, ...
Nature 578 (7796), 627-630, 2020
1062020
Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism
BG Lee, F Merkel, M Allegretti, M Hassler, C Cawood, L Lecomte, ...
Nature structural & molecular biology 27 (8), 743-751, 2020
892020
Structure of the Fanconi anaemia monoubiquitin ligase complex
S Shakeel, E Rajendra, P Alcón, F O’Reilly, DS Chorev, S Maslen, ...
Nature 575 (7781), 234-237, 2019
892019
Reliable identification of protein-protein interactions by crosslinking mass spectrometry
S Lenz, LR Sinn, FJ O’Reilly, L Fischer, F Wegner, J Rappsilber
Nature communications 12 (1), 3564, 2021
852021
In situ structural restraints from cross-linking mass spectrometry in human mitochondria
PSJ Ryl, M Bohlke-Schneider, S Lenz, L Fischer, L Budzinski, M Stuiver, ...
Journal of Proteome Research 19 (1), 327-336, 2019
562019
Protein complexes in cells by AI‐assisted structural proteomics
FJ O'Reilly, A Graziadei, C Forbrig, R Bremenkamp, K Charles, S Lenz, ...
Molecular Systems Biology 19 (4), e11544, 2023
522023
Purified Smc5/6 complex exhibits DNA substrate recognition and compaction
P Gutierrez-Escribano, S Hormeño, J Madariaga-Marcos, R Solé-Soler, ...
Molecular Cell 80 (6), 1039-1054. e6, 2020
522020
Integrative structure of a 10-megadalton eukaryotic pyruvate dehydrogenase complex from native cell extracts
FL Kyrilis, DA Semchonok, I Skalidis, C Tüting, F Hamdi, FJ O’Reilly, ...
Cell Reports 34 (6), 2021
412021
mRNA recognition and packaging by the human transcription–export complex
B Pacheco-Fiallos, MK Vorländer, D Riabov-Bassat, L Fin, FJ O’Reilly, ...
Nature 616 (7958), 828-835, 2023
312023
Cryo‐EM reveals the complex architecture of dynactin's shoulder region and pointed end
CK Lau, FJ O’Reilly, B Santhanam, SE Lacey, J Rappsilber, AP Carter
The EMBO journal 40 (8), e106164, 2021
232021
Improved peptide backbone fragmentation is the primary advantage of MS-cleavable crosslinkers
L Kolbowski, S Lenz, L Fischer, LR Sinn, FJ O’Reilly, J Rappsilber
Analytical Chemistry 94 (22), 7779-7786, 2022
162022
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